Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Theodomir Dusabimana"'
Publikováno v:
Cell Death and Disease, Vol 14, Iss 7, Pp 1-14 (2023)
Abstract Sepsis is a serious clinical condition characterized by a systemic inflammatory response, a leading cause of acute liver and kidney injury, and is associated with a high morbidity and mortality. Understanding the molecular mechanisms underly
Externí odkaz:
https://doaj.org/article/36be7c62e41f4223abf31f1784d88f29
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 14295 (2023)
Renal ischemia–reperfusion (IR) causes acute kidney injury due to oxidative stress, tubular inflammation, and apoptosis. Early growth response 1 (Egr-1) is a transcription factor belonging to the immediate early gene family and is known to regulate
Externí odkaz:
https://doaj.org/article/26c4d13bdcf5451f82dd6c4b2effb33f
Autor:
Eun Jung Park, Jihyun Je, Theodomir Dusabimana, Seung Pil Yun, Hye Jung Kim, Hwajin Kim, Sang Won Park
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3413 (2023)
Renal ischemia reperfusion (IR) injury is a major cause of acute kidney injury (AKI) that is often complicated by multiple organ failure of the liver and intestine. The mineralocorticoid receptor (MR) is activated in patients with renal failure assoc
Externí odkaz:
https://doaj.org/article/de44260743b2432abf49b5c3b566335a
Autor:
Eun Jung Park, Jihyun Je, Theodomir Dusabimana, Seung Pil Yun, Hye Jung Kim, Hwajin Kim, Sang Won Park
Publikováno v:
Biomedicines, Vol 10, Iss 12, p 3048 (2022)
Homocysteine (Hcy), a homologue of cysteine, is biosynthesized during methionine metabolism. Elevated plasma Hcy is associated with glomerular injury and considered as a risk factor for renal dysfunction, predicting incident chronic kidney disease. H
Externí odkaz:
https://doaj.org/article/54f06cca08c542e2a47c2a7b8475a6e6
Publikováno v:
Experimental and Molecular Medicine, Vol 51, Iss 4, Pp 1-16 (2019)
Liver injury: Citrus peel to the rescue Nobiletin, an antioxidant found in citrus peel, may protect the liver from reperfusion injury, damage following blood flow interruption. When blood flow is restricted and then restored, as in transplant, surger
Externí odkaz:
https://doaj.org/article/5783eb558bbe4d4bbcf670f0f0c2bdee
Autor:
Theodomir Dusabimana, So Ra Kim, Eun Jung Park, Jihyun Je, Kyuho Jeong, Seung Pil Yun, Hye Jung Kim, Hwajin Kim, Sang Won Park
Publikováno v:
Molecular Metabolism, Vol 42, Iss , Pp 101089- (2020)
Objective: Diabetic nephropathy (DN) is one of the most common complications of diabetes and a critical risk factor for developing end-stage renal disease. Activation of purinergic receptors, including P2Y2R has been associated with the pathogenesis
Externí odkaz:
https://doaj.org/article/a2941e251b6042079222d83568b7c0fc
Autor:
Theodomir Dusabimana, Eun Jung Park, Jihyun Je, Kyuho Jeong, Seung Pil Yun, Hye Jung Kim, Hwajin Kim, Sang Won Park
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 5528 (2021)
Non-alcoholic fatty liver disease (NAFLD) is a chronic metabolic liver disease associated with obesity and insulin resistance. Activation of the purinergic receptor P2Y2R has been reported to promote adipogenesis, inflammation and dyslipidemia in adi
Externí odkaz:
https://doaj.org/article/9d0185334f6443ab9bebdce696872902
Autor:
Theodomir Dusabimana, Eun Jung Park, Jihyun Je, Kyuho Jeong, Seung Pil Yun, Hye Jung Kim, Hwajin Kim, Sang Won Park
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 4, p 1651 (2021)
Diabetic nephropathy (DN) is a common pathological feature in patients with diabetes and the leading cause of end-stage renal disease. Although several pharmacological agents have been developed, the management of DN remains challenging. Geniposide,
Externí odkaz:
https://doaj.org/article/3e740c6f338b4141937ea911e3649768
Autor:
Eun Jung Park, Theodomir Dusabimana, Jihyun Je, Kyuho Jeong, Seung Pil Yun, Hye Jung Kim, Hwajin Kim, Sang Won Park
Publikováno v:
Biomedicines, Vol 8, Iss 9, p 352 (2020)
Glutathione (GSH) is an endogenous antioxidant found in plants, animals, fungi, and some microorganisms that protects cells by neutralizing hydrogen peroxide. Honokiol, an active ingredient of Magnolia officinalis, is known for antioxidant, anti-infl
Externí odkaz:
https://doaj.org/article/89b1420776d1436094f5e797eacbf9d9
Autor:
So Ra Kim, Eun Jung Park, Theodomir Dusabimana, Jihyun Je, Kyuho Jeong, Seung Pil Yun, Hye Jung Kim, Kye Man Cho, Hwajin Kim, Sang Won Park
Publikováno v:
Nutrients, Vol 12, Iss 9, p 2802 (2020)
Endotoxin-induced acute liver injury is mediated by an excessive inflammatory response, hepatocellular oxidative stress, and apoptosis. Traditional medicinal plants have been used to treat various disorders. Platycodon grandifloras (PG) has been show
Externí odkaz:
https://doaj.org/article/7cce94fdcbcb4bc8b638bd252b6ac452