Zobrazeno 1 - 10
of 144
pro vyhledávání: '"Theo Verrips"'
Autor:
Angela I. Schriek, Marlies M. van Haaren, Meliawati Poniman, Gillian Dekkers, Arthur E. H. Bentlage, Marloes Grobben, Gestur Vidarsson, Rogier W. Sanders, Theo Verrips, Teunis B. H. Geijtenbeek, Raimond Heukers, Neeltje A. Kootstra, Steven W. de Taeye, Marit J. van Gils
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/ca4f0b22e0c048fb9ae67a69af492c55
Autor:
Angela I. Schriek, Marlies M. van Haaren, Meliawati Poniman, Gillian Dekkers, Arthur E. H. Bentlage, Marloes Grobben, Gestur Vidarsson, Rogier W. Sanders, Theo Verrips, Teunis B. H. Geijtenbeek, Raimond Heukers, Neeltje A. Kootstra, Steven W. de Taeye, Marit J. van Gils
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The most effective treatment for HIV-1, antiretroviral therapy, suppresses viral replication and averts the disease from progression. Nonetheless, there is a need for alternative treatments as it requires daily administration with the possibility of
Externí odkaz:
https://doaj.org/article/c2cef343f4a24ae19aaa9f5cce0e8c24
Autor:
Nika M. Strokappe, Miriam Hock, Lucy Rutten, Laura E. Mccoy, Jaap W. Back, Christophe Caillat, Matthias Haffke, Robin A. Weiss, Winfried Weissenhorn, Theo Verrips
Publikováno v:
Antibodies, Vol 8, Iss 2, p 38 (2019)
Broad and potent neutralizing llama single domain antibodies (VHH) against HIV-1 targeting the CD4 binding site (CD4bs) have previously been isolated upon llama immunization. Here we describe the epitopes of three additional VHH groups selected from
Externí odkaz:
https://doaj.org/article/2e8d01ac0ce44807b40322c7b3eaad84
Autor:
Laura E McCoy, Lucy Rutten, Dan Frampton, Ian Anderson, Luke Granger, Rachael Bashford-Rogers, Gillian Dekkers, Nika M Strokappe, Michael S Seaman, Willie Koh, Vanina Grippo, Alexander Kliche, Theo Verrips, Paul Kellam, Ariberto Fassati, Robin A Weiss
Publikováno v:
PLoS Pathogens, Vol 10, Iss 12, p e1004552 (2014)
To date, no immunization of humans or animals has elicited broadly neutralizing sera able to prevent HIV-1 transmission; however, elicitation of broad and potent heavy chain only antibodies (HCAb) has previously been reported in llamas. In this study
Externí odkaz:
https://doaj.org/article/83f2d3d6e15349dfb005fad45ed70627
Autor:
Nika Strokappe, Agnieszka Szynol, Marlèn Aasa-Chapman, Andrea Gorlani, Anna Forsman Quigley, David Lutje Hulsik, Lei Chen, Robin Weiss, Hans de Haard, Theo Verrips
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33298 (2012)
Many of the neutralising antibodies, isolated to date, display limited activities against the globally most prevalent HIV-1 subtypes A and C. Therefore, those subtypes are considered to be an important target for antibody-based therapy. Variable doma
Externí odkaz:
https://doaj.org/article/95c6cab2498e49dab1a65a266b6337cd
Autor:
Andreas Hinz, David Lutje Hulsik, Anna Forsman, Willie Wee-Lee Koh, Hassan Belrhali, Andrea Gorlani, Hans de Haard, Robin A Weiss, Theo Verrips, Winfried Weissenhorn
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10482 (2010)
HIV-1 entry into host cells is mediated by the sequential binding of the envelope glycoprotein gp120 to CD4 and a chemokine receptor. Antibodies binding to epitopes overlapping the CD4-binding site on gp120 are potent inhibitors of HIV entry, such as
Externí odkaz:
https://doaj.org/article/cc4438b984d14872b7496273180a0aa0
Autor:
Kausilia K. Krishnadath, Hergen Spits, Jan Paul Medema, C. Theo Verrips, Edward Dolk, Cheryl Zimberlin, Lucy Rutten, Mohamed El Khattabi, Koen Wagner, Silvia Calpe
Epitope mapping using BMP heterodimers (BMP4/7, BMP2/6 and BMP2/7).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47a79b48202f3b0898ee281ba858eac0
https://doi.org/10.1158/1535-7163.22501663
https://doi.org/10.1158/1535-7163.22501663
Autor:
Kausilia K. Krishnadath, Hergen Spits, Jan Paul Medema, C. Theo Verrips, Edward Dolk, Cheryl Zimberlin, Lucy Rutten, Mohamed El Khattabi, Koen Wagner, Silvia Calpe
Bone morphogenetic proteins (BMP) have important but distinct roles in tissue homeostasis and disease, including carcinogenesis and tumor progression. A large number of BMP inhibitors are available to study BMP function; however, as most of these ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10d83c17fc91e5e3adde4774a0324064
https://doi.org/10.1158/1535-7163.c.6536857.v1
https://doi.org/10.1158/1535-7163.c.6536857.v1
Autor:
Kausilia K. Krishnadath, Hergen Spits, Jan Paul Medema, C. Theo Verrips, Edward Dolk, Cheryl Zimberlin, Lucy Rutten, Mohamed El Khattabi, Koen Wagner, Silvia Calpe
Supplementary file containing Supplementary materials and methods, supplementary figure legends and supplementary references.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::404265aa745e8b042e9e9f3c4b08f87e
https://doi.org/10.1158/1535-7163.22501660.v1
https://doi.org/10.1158/1535-7163.22501660.v1
Autor:
Kausilia K. Krishnadath, Hergen Spits, Jan Paul Medema, C. Theo Verrips, Edward Dolk, Cheryl Zimberlin, Lucy Rutten, Mohamed El Khattabi, Koen Wagner, Silvia Calpe
Summary of epitope binning experiments of the VHHs and controls
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::973d561ed6d3a9847aeff23646344834
https://doi.org/10.1158/1535-7163.22501657.v1
https://doi.org/10.1158/1535-7163.22501657.v1