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pro vyhledávání: '"Theo Roumeliotis"'
Autor:
Cornelia Meisenberg, Daphné Morel, Marlène Garrido, Jyoti S. Choudhary, Theo Roumeliotis, Sophie Postel-Vinay, Asha Konde, Andrew Lamb, Thomas Eychenne, Samuel Jouny, Ilirjana Bajrami, Léo Colmet-Daage, Clémence Astier, Jessica A. Downs, Roman M. Chabanon, Jean-Charles Soria, Nicolas Dorvault, Suzanna R. Hopkins, Geneviève Almouzni, Christopher J. Lord
Publikováno v:
Cancer Research. 80:1058-1058
Aim: Polybromo-1 (PBRM1), a specific subunit of the pBAF chromatin remodeling complex, is frequently inactivated in cancer. For example, 40% of clear cell Renal Cell Carcinoma (ccRCC) and 15% of cholangiocarcinoma present deleterious PBRM1 mutations.