Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Theo M. de Kok"'
Publikováno v:
Environment International, Vol 186, Iss , Pp 108642- (2024)
Parkinson's disease (PD) is a complex neurodegenerative disorder influenced by genetic factors and environmental exposures. Polychlorinated biphenyls (PCBs), a group of synthetic organic compounds, have been identified as potential environmental risk
Externí odkaz:
https://doaj.org/article/9b7c6a2203ba4d12be90bde5300e57d0
Autor:
Julia N. DeBenedictis, Courtney Murrell, Duncan Hauser, Marcel van Herwijnen, Bart Elen, Theo M. de Kok, Simone G. van Breda
Publikováno v:
Antioxidants, Vol 13, Iss 8, p 915 (2024)
Adequate fruit and vegetable (F and V) intake, as recommended by the World Health Organization (over 400 g/day), is linked to reduced chronic disease risk. However, human intervention trials, especially with whole F and V and in complex combinations,
Externí odkaz:
https://doaj.org/article/7fbb792b3ab9451b885b082418e8056e
Autor:
Daan van Beek, Job Verdonschot, Kasper Derks, Han Brunner, Theo M. de Kok, Ilja C. W. Arts, Stephane Heymans, Martina Kutmon, Michiel Adriaens
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Allele-specific expression (ASE) analysis detects the relative abundance of alleles at heterozygous loci as a proxy for cis-regulatory variation, which affects the personal transcriptome and proteome. This study describes the development and
Externí odkaz:
https://doaj.org/article/39b6c258cea04013a7a8a15b1d60088e
Autor:
Rossella Alfano, Daniela Zugna, Henrique Barros, Mariona Bustamante, Leda Chatzi, Akram Ghantous, Zdenko Herceg, Pekka Keski-Rahkonen, Theo M. de Kok, Tim S Nawrot, Caroline L Relton, Oliver Robinson, Theano Roumeliotaki, Augustin Scalbert, Martine Vrijheid, Paolo Vineis, Lorenzo Richiardi, Michelle Plusquin
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-20 (2023)
Abstract Background Rapid postnatal growth may result from exposure in utero or early life to adverse conditions and has been associated with diseases later in life and, in particular, with childhood obesity. DNA methylation, interfacing early-life e
Externí odkaz:
https://doaj.org/article/b375e003676f40249a2bc749b737791f
Autor:
Qingfeng Wen, Marcha Verheijen, Mandy Melissa Jane Wittens, Julia Czuryło, Sebastiaan Engelborghs, Duncan Hauser, Marcel H. M. van Herwijnen, Thomas Lundh, Ingvar A. Bergdahl, Soterios A. Kyrtopoulos, Theo M. de Kok, Hubert J. M. Smeets, Jacco Jan Briedé, Julian Krauskopf
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Alzheimer’s disease (AD) is a neurodegenerative disease that eventually affects memory and behavior. The identification of biomarkers based on risk factors for AD provides insight into the disease since the exact cause of AD remains unknow
Externí odkaz:
https://doaj.org/article/589120a69fb14af5a26846ca70d30555
Autor:
Nicolaj S. Bischoff, Héloïse Proquin, Marlon J. Jetten, Yannick Schrooders, Marloes C. M. Jonkhout, Jacco J. Briedé, Simone G. van Breda, Danyel G. J. Jennen, Estefany I. Medina-Reyes, Norma L. Delgado-Buenrostro, Yolanda I. Chirino, Henk van Loveren, Theo M. de Kok
Publikováno v:
Nanomaterials, Vol 13, Iss 21, p 2888 (2023)
In the published publication [...]
Externí odkaz:
https://doaj.org/article/c8548edcf51f4851b932093df2b10c62
Publikováno v:
Antioxidants, Vol 12, Iss 6, p 1252 (2023)
Foods high in phytochemicals are known for their role in the prevention of chronic disease development, but after processing and storage, such food products may lose part of their functionality as these compounds are sensitive to the impact of proces
Externí odkaz:
https://doaj.org/article/f907ebdfe723461da134163fca57acb9
Autor:
Maria Tsamou, Karen Vrijens, Congrong Wang, Ellen Winckelmans, Kristof Y. Neven, Narjes Madhloum, Theo M. de Kok, Tim S. Nawrot
Publikováno v:
Epigenetics, Vol 16, Iss 4, Pp 373-388 (2021)
There is an increasing interest in microRNAs (miRNAs) as they are of utmost importance in gene regulation at the posttranscriptional level. Sex-related susceptibility for non-communicable diseases later in life could originate in early life. Until no
Externí odkaz:
https://doaj.org/article/248c897094ed4a6aaa68dfecb1ffb286
Autor:
Nicolaj S. Bischoff, Héloïse Proquin, Marlon J. Jetten, Yannick Schrooders, Marloes C. M. Jonkhout, Jacco J. Briedé, Simone G. van Breda, Danyel G. J. Jennen, Estefany I. Medina-Reyes, Norma L. Delgado-Buenrostro, Yolanda I. Chirino, Henk van Loveren, Theo M. de Kok
Publikováno v:
Nanomaterials, Vol 13, Iss 9, p 1552 (2023)
We appreciate the interest in our article describing transcriptome changes in a transgenic mouse model carrying an APC gene mutation and would like to reply to the reader [...]
Externí odkaz:
https://doaj.org/article/b88bc0b67aea469da3f6bec087dad66d
Autor:
Simone G. van Breda, Karen Mathijs, Virág Sági-Kiss, Gunter G. Kuhnle, Ben van der Veer, Rena R. Jones, Rashmi Sinha, Mary H. Ward, Theo M. de Kok
Publikováno v:
Environmental Health, Vol 18, Iss 1, Pp 1-12 (2019)
Abstract Background Nitrate is converted to nitrite in the human body and subsequently can react with amines and amides in the gastrointestinal tract to form N-nitroso compounds (NOCs), which are known to be carcinogenic in animals. Humans can be exp
Externí odkaz:
https://doaj.org/article/121c777d0d814fdda21b7a250fe8d2e9