Zobrazeno 1 - 10
of 190
pro vyhledávání: '"Theo K. Bammler"'
Autor:
Kevin A. Lidberg, Kendan Jones-Isaac, Jade Yang, Jacelyn Bain, Lu Wang, James W. MacDonald, Theo K. Bammler, Justina Calamia, Kenneth E. Thummel, Catherine K. Yeung, Stefanie Countryman, Paul Koenig, Jonathan Himmelfarb, Edward J. Kelly
Publikováno v:
npj Microgravity, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract The microgravity environment aboard the International Space Station (ISS) provides a unique stressor that can help understand underlying cellular and molecular drivers of pathological changes observed in astronauts with the ultimate goals of
Externí odkaz:
https://doaj.org/article/080dc77d0559426aa337057d6101081e
Publikováno v:
Glomerular Diseases, Vol 4, Iss 1, Pp 49-63 (2024)
Background: The first spatially resolved transcriptomics platforms, GeoMx (Nanostring) and Visium (10x Genomics) were launched in 2019 and were recognized as the method of the year by Nature Methods in 2020. The subsequent refinement and expansion of
Externí odkaz:
https://doaj.org/article/74aa88bd3b7b4200ac6804f26a76fdbf
Autor:
Daniel A. Enquobahrie, James MacDonald, Michael Hussey, Theo K. Bammler, Christine T. Loftus, Alison G. Paquette, Nora Byington, Carmen J. Marsit, Adam Szpiro, Joel D. Kaufman, Kaja Z. LeWinn, Nicole R. Bush, Frances Tylavsky, Catherine J. Karr, Sheela Sathyanarayana
Publikováno v:
Environment International, Vol 165, Iss , Pp 107310- (2022)
Background: While strong evidence supports adverse maternal and offspring consequences of air pollution, mechanisms that involve the placenta, a key part of the intrauterine environment, are largely unknown. Previous studies of air pollution and plac
Externí odkaz:
https://doaj.org/article/53e1dc16420d44d4b53a66ad58439927
Autor:
An N. Massaro, Theo K. Bammler, James W. MacDonald, Krystle M. Perez, Bryan Comstock, Sandra E. Juul
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Preterm birth remains the leading identifiable risk factor for cerebral palsy (CP), a devastating form of motor impairment due to developmental brain injury occurring around the time of birth. We performed genome wide methylation and whole t
Externí odkaz:
https://doaj.org/article/fcea0f7077dc4ee3b7e684612a03d384
Autor:
Kevin A. Lidberg, Andrew J. Annalora, Marija Jozic, Daniel J. Elson, Lu Wang, Theo K. Bammler, Susanne Ramm, Maria Beatriz Monteiro, Jonathan Himmelfarb, Craig B. Marcus, Patrick L. Iversen, Edward J. Kelly
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-20 (2021)
Abstract CYP3A5 is the primary CYP3A subfamily enzyme expressed in the human kidney and its aberrant expression may contribute to a broad spectrum of renal disorders. Pharmacogenetic studies have reported inconsistent linkages between CYP3A5 expressi
Externí odkaz:
https://doaj.org/article/a3c201a0a7084bb899171d4e7331ae73
Autor:
Christopher M. Schaupp, Dianne Botta, Collin C. White, David K. Scoville, Sengkeo Srinouanprachanh, Theo K. Bammler, James MacDonald, Terrance J. Kavanagh
Publikováno v:
Redox Biology, Vol 49, Iss , Pp 102213- (2022)
Antioxidant signaling/communication is among the most important cellular defense and survival pathways, and the importance of redox signaling and homeostasis in aging has been well-documented. Intracellular levels of glutathione (GSH), a very importa
Externí odkaz:
https://doaj.org/article/d20c70f4fe0e4b73a8d082327e1a98bc
Autor:
Daryl M. Okamura, Chris M. Brewer, Paul Wakenight, Nadia Bahrami, Kristina Bernardi, Amy Tran, Jill Olson, Xiaogang Shi, Szu-Ying Yeh, Adrian Piliponsky, Sarah J. Collins, Elizabeth D. Nguyen, Andrew E. Timms, James W. MacDonald, Theo K. Bammler, Branden R. Nelson, Kathleen J. Millen, David R. Beier, Mark W. Majesky
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103269- (2021)
Summary: Fibrosis-driven solid organ failure is an enormous burden on global health. Spiny mice (Acomys) are terrestrial mammals that can regenerate severe skin wounds without scars to avoid predation. Whether spiny mice also regenerate internal orga
Externí odkaz:
https://doaj.org/article/14339f301a224e7fbcad8ed0416f3953
Autor:
Thomas R. Wood, Pratik Parikh, Bryan A. Comstock, Janessa B. Law, Theo K. Bammler, Karl C. Kuban, Dennis E. Mayock, Patrick J. Heagerty, Sandra Juul, MD, PhD
Publikováno v:
EBioMedicine, Vol 72, Iss , Pp 103605- (2021)
ABSTRACT: Background: In the Preterm Erythropoietin (Epo) NeUroproTection (PENUT) Trial, potential biomarkers of neurological injury were measured to determine their association with outcomes at two years of age and whether Epo treatment decreased ma
Externí odkaz:
https://doaj.org/article/4b0a8003e40e499499bc13382379db8b
Publikováno v:
Particle and Fibre Toxicology, Vol 16, Iss 1, Pp 1-12 (2019)
Abstract Background Developmental exposure to particulate matter air pollution is harmful to cardiovascular health, but the mechanisms by which this exposure mediates susceptibility to heart disease is poorly understood. We have previously shown, in
Externí odkaz:
https://doaj.org/article/6c8109b65d684ba7bcfacd9aa3c8493e
Autor:
Olena Korvatska, Kostantin Kiianitsa, Alexander Ratushny, Mark Matsushita, Neal Beeman, Wei-Ming Chien, Jun-Ichi Satoh, Michael O. Dorschner, C. Dirk Keene, Theo K. Bammler, Thomas D. Bird, Wendy H. Raskind
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The R47H variant in the microglial triggering receptor expressed on myeloid cell 2 (TREM2) receptor is a strong risk factor for Alzheimer’s disease (AD). To characterize processes affected by R47H, we performed an integrative network analysis of ge
Externí odkaz:
https://doaj.org/article/473307c7b17f4f2c97dff1c8062620f1