Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Theo J C van Berkel"'
Autor:
Erik van Kampen, Olivier Beaslas, Reeni B Hildebrand, Bart Lammers, Theo J C Van Berkel, Vesa M Olkkonen, Miranda Van Eck
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109024 (2014)
INTRODUCTION: Oxysterol binding protein Related Proteins (ORPs) mediate intracellular lipid transport and homeostatic regulation. ORP8 downregulates ABCA1 expression in macrophages and cellular cholesterol efflux to apolipoprotein A-I. In line, ORP8
Externí odkaz:
https://doaj.org/article/2121587ad62b451485dd65b5d379df5e
Autor:
Carlos L J Vrins, Ruud Out, Peter van Santbrink, André van der Zee, Tokameh Mahmoudi, Martine Groenendijk, Louis M Havekes, Theo J C van Berkel, Ko Willems van Dijk, Erik A L Biessen
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57492 (2013)
BACKGROUND: The zinc finger protein Znf202 is a transcriptional suppressor of lipid related genes and has been linked to hypoalphalipoproteinemia. A functional role of Znf202 in lipid metabolism in vivo still remains to be established. METHODOLOGY AN
Externí odkaz:
https://doaj.org/article/f27b3ab967384e6da9e293fa14bed075
Autor:
Martine Bot, Paul P Van Veldhoven, Saskia C A de Jager, Jason Johnson, Niels Nijstad, Peter J Van Santbrink, Marijke M Westra, Gerd Van Der Hoeven, Marion J Gijbels, Carsten Müller-Tidow, Georg Varga, Uwe J F Tietge, Johan Kuiper, Theo J C Van Berkel, Jerzy-Roch Nofer, Ilze Bot, Erik A L Biessen
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63360 (2013)
Altered sphingosine 1-phosphate (S1P) homeostasis and signaling is implicated in various inflammatory diseases including atherosclerosis. As S1P levels are tightly controlled by S1P lyase, we investigated the impact of hematopoietic S1P lyase (Sgpl1(
Externí odkaz:
https://doaj.org/article/1a0d95655b81411ea2e0c24d8f384462
Autor:
Saskia C A de Jager, Brenda W C Bongaerts, Michael Weber, Adriaan O Kraaijeveld, Mat Rousch, Stefanie Dimmeler, Marja P van Dieijen-Visser, Kitty B J M Cleutjens, Patty J Nelemans, Theo J C van Berkel, Erik A L Biessen
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45804 (2012)
Cytokines play an important role in ischemic injury and repair. However, little is known about their prognostic value in cardiovascular disease. The aim of this study was to investigate the prognostic importance of chemokines CCL3/MIP-1α, CCL5/RANTE
Externí odkaz:
https://doaj.org/article/a245f1e15c894d60856f4a3540d041e6
Autor:
Illiana Meurs, Laura Calpe-Berdiel, Kim L L Habets, Ying Zhao, Suzanne J A Korporaal, A Mieke Mommaas, Emmanuelle Josselin, Reeni B Hildebrand, Dan Ye, Ruud Out, Johan Kuiper, Theo J C Van Berkel, Giovanna Chimini, Miranda Van Eck
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e30984 (2012)
ABCA7, a close relative of ABCA1 which facilitates cholesterol efflux to lipid-poor apoproteins, has been implicated in macrophage lipid efflux and clearance of apoptotic cells in in vitro studies. In the current study, we investigated the in vivo ef
Externí odkaz:
https://doaj.org/article/d1f323edcd304136bc70ba35fa4b31bb
Autor:
Kasinath Viswanathan, Ilze Bot, Liying Liu, Erbin Dai, Peter C Turner, Babajide Togonu-Bickersteth, Jakob Richardson, Jennifer A Davids, Jennifer M Williams, Mee Y Bartee, Hao Chen, Theo J C van Berkel, Erik A L Biessen, Richard W Moyer, Alexandra R Lucas
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44694 (2012)
Poxviruses express highly active inhibitors, including serine proteinase inhibitors (serpins), designed to target host immune defense pathways. Recent work has demonstrated clinical efficacy for a secreted, myxomaviral serpin, Serp-1, which targets t
Externí odkaz:
https://doaj.org/article/a5c6acf97d6f48ee9d839410654d30f7
Autor:
Bart Lammers, Ying Zhao, Amanda C Foks, Reeni B Hildebrand, Johan Kuiper, Theo J C Van Berkel, Miranda Van Eck
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e48080 (2012)
ATP-binding cassette transporter A1 (ABCA1) is an important mediator of macrophage cholesterol efflux. It mediates the efflux of cellular cholesterol to lipid-poor apolipoprotein A-I. LDL receptor (LDLr) knockout (KO) mice deficient for leukocyte ABC
Externí odkaz:
https://doaj.org/article/bef2f50d46114fbb99d7838faa1cf370
Autor:
Bart Lammers, Ying Zhao, Menno Hoekstra, Reeni B Hildebrand, Dan Ye, Illiana Meurs, Theo J C Van Berkel, Miranda Van Eck
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26095 (2011)
ABCA1 protects against atherosclerosis by facilitating cholesterol efflux from macrophage foam cells in the arterial wall to extracellular apolipoprotein (apo) A-I. In contrast to apoA-I, apoE is secreted by macrophages and can, like apoA-I, induce A
Externí odkaz:
https://doaj.org/article/7b6dc0eabffb484f9d460eb8f267070c
Autor:
Anjana Singh, Adriaan O. Kraaijeveld, Adelina Curaj, Kanin Wichapong, Linda Hammerich, Saskia C. A. de Jager, Ilze Bot, Sergei P. Atamas, Theo J. C. van Berkel, J. Wouter Jukema, Iain Comerford, Shaun R. McColl, Barend Mees, Johan W. M. Heemskerk, Gerry A. F. Nicolaes, Tilman Hackeng, Elisa Anamaria Liehn, Frank Tacke, Erik A. L. Biessen
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe CC chemokine ligand 18 (CCL18) is a chemokine highly expressed in chronic inflammation in humans. Recent observations of elevated CCL18 plasma levels in patients with acute cardiovascular syndromes prompted an investigation into the r
Externí odkaz:
https://doaj.org/article/573017efcc53412a84624e171b71058e
Autor:
Filip M E, Segers, Adele V, Ruder, Marijke M, Westra, Twan, Lammers, Seyed Mohammadali, Dadfar, Karolin, Roemhild, Tin Sing, Lam, M, Eline Kooi, Kitty B J M, Cleutjens, Fons K, Verheyen, Geert W H, Schurink, Guido R, Haenen, Theo J C, van Berkel, Ilze, Bot, Bente, Halvorsen, Judith C, Sluimer, Erik A L, Biessen
Publikováno v:
Cardiovascular research.
(Ultra) Small superparamagnetic iron oxide nanoparticles, (U)SPIO, are widely used as magnetic resonance imaging contrast media and assumed to be safe for clinical applications in cardiovascular disease. As safety tests largely relied on normolipidem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eabb546308a5bcf22d3d0a72d753b7e5
https://pubmed.ncbi.nlm.nih.gov/35325057
https://pubmed.ncbi.nlm.nih.gov/35325057