Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Theo H. Reijmers"'
Autor:
Herman A van Wietmarschen, Weidong Dai, Anita J van der Kooij, Theo H Reijmers, Yan Schroën, Mei Wang, Zhiliang Xu, Xinchang Wang, Hongwei Kong, Guowang Xu, Thomas Hankemeier, Jacqueline J Meulman, Jan van der Greef
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44331 (2012)
OBJECTIVE: The aim is to characterize subgroups or phenotypes of rheumatoid arthritis (RA) patients using a systems biology approach. The discovery of subtypes of rheumatoid arthritis patients is an essential research area for the improvement of resp
Externí odkaz:
https://doaj.org/article/139225ee5a8c4eea90eecc06d54e9eca
Autor:
Heng Wei, Chunxiu Hu, Mei Wang, Anita M van den Hoek, Theo H Reijmers, Suzan Wopereis, Jildau Bouwman, Raymond Ramaker, Henrie A A J Korthout, Marco Vennik, Thomas Hankemeier, Louis M Havekes, Renger F Witkamp, Elwin R Verheij, Guowang Xu, Jan van der Greef
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30332 (2012)
Causes and consequences of the complex changes in lipids occurring in the metabolic syndrome are only partly understood. Several interconnected processes are deteriorating, which implies that multi-target approaches might be more successful than stra
Externí odkaz:
https://doaj.org/article/97a7f9431fa84e7993d920a6308f055a
Autor:
Chunxiu Hu, Heng Wei, Anita M van den Hoek, Mei Wang, Rob van der Heijden, Gerwin Spijksma, Theo H Reijmers, Jildau Bouwman, Suzan Wopereis, Louis M Havekes, Elwin Verheij, Thomas Hankemeier, Guowang Xu, Jan van der Greef
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19423 (2011)
Lipids are known to play crucial roles in the development of life-style related risk factors such as obesity, dyslipoproteinemia, hypertension and diabetes. The first selective cannabinoid-1 receptor blocker rimonabant, an anorectic anti-obesity drug
Externí odkaz:
https://doaj.org/article/5f632fcc65ec4cf5b76fba16d29411b6
Autor:
Herman A van Wietmarschen, Theo H Reijmers, Anita J van der Kooij, Jan Schroën, Heng Wei, Thomas Hankemeier, Jacqueline J Meulman, Jan van der Greef
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24846 (2011)
The future of personalized medicine depends on advanced diagnostic tools to characterize responders and non-responders to treatment. Systems diagnosis is a new approach which aims to capture a large amount of symptom information from patients to char
Externí odkaz:
https://doaj.org/article/e3d36c6841f142a2b1173f6c39a72598
Publikováno v:
Analytica Chimica Acta. 801:34-42
Because of its high sensitivity and specificity, hyphenated mass spectrometry has become the predominant method to detect and quantify metabolites present in bio-samples relevant for all sorts of life science studies being executed. In contrast to ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::363d0e325b98eeca3b07f1c9ca1d5ab8
https://doi.org/10.1016/j.aca.2013.09.028
https://doi.org/10.1016/j.aca.2013.09.028
Autor:
Huub C. J. Hoefsloot, Age K. Smilde, Frank Suits, Theo H. Reijmers, Gooitzen Zwanenburg, Vikram Mitra, Natalia Govorukhina, Ate G.J. van der Zee, Peter Horvatovich, Inge Westra, Rainer Bischoff
Publikováno v:
Analytical Chemistry, 88(8), 4229-4238. American Chemical Society
Analytical Chemistry, 88(8), 4229-4238. AMER CHEMICAL SOC INC
Analytical Chemistry, 88(8), 4229-4238. AMER CHEMICAL SOC INC
Complex shotgun proteomics peptide profiles obtained in quantitative differential protein expression studies, such as in biomarker discovery, may be affected by multiple experimental factors. These preanalytical factors may affect the measured protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9bc0182a9ddea4993973fc1ead015b0
https://dare.uva.nl/personal/pure/en/publications/identification-of-analytical-factors-affecting-complex-proteomics-profiles-acquired-in-a-factorial-design-study-with-analysis-of-variance(a1d17139-05dd-4b64-b313-e7e893772235).html
https://dare.uva.nl/personal/pure/en/publications/identification-of-analytical-factors-affecting-complex-proteomics-profiles-acquired-in-a-factorial-design-study-with-analysis-of-variance(a1d17139-05dd-4b64-b313-e7e893772235).html
Autor:
Guowang Xu, Robert van der Heijden, Mei Wang, Jan van der Greef, Thomas Hankemeier, Theo H. Reijmers, Jiangshan Wang, Gerwin Spijksma
Publikováno v:
Journal of Chromatography A, 11, 1216, 2169-2178
A matrix-assisted laser desorption ionization mass spectrometry (MALDI-MS) method was developed for the high throughput and robust qualitative profiling of alkaloids in Fuzi-the processed lateral roots of the Chinese herbal medicine Aconitum carmicha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a41b7cfa02c087a912516be6dcb77107
https://doi.org/10.1016/j.chroma.2008.11.077
https://doi.org/10.1016/j.chroma.2008.11.077
Autor:
J. van der Greef, Ivana Bobeldijk-Pastorova, Jacqueline J. Meulman, Meike Bartels, Dorret I. Boomsma, Harmen H.M. Draisma, Theo H. Reijmers, Thomas Hankemeier, Raymond Ramaker, G.F. van Burk
Publikováno v:
OMICS: A Journal of Integrative Biology, 12(1), 17-31. Mary Ann Liebert Inc.
OMICS A Journal of Integrative Biology, 1, 12, 17-31
Draisma, H H M, Reijmers, T H, Bobeldijk-Pastorova, I, Meulman, J J, van Burk, G F, Bartels, M, Ramaker, R, van der Greef, J, Boomsma, D I & Hankemeier, T 2008, ' Similarities and differences in lipidomics profiles among healthy monozygotic twin pairs. ', OMICS: A Journal of Integrative Biology, vol. 12, no. 1, pp. 17-31 . https://doi.org/10.1089/omi.2007.0048
OMICS A Journal of Integrative Biology, 1, 12, 17-31
Draisma, H H M, Reijmers, T H, Bobeldijk-Pastorova, I, Meulman, J J, van Burk, G F, Bartels, M, Ramaker, R, van der Greef, J, Boomsma, D I & Hankemeier, T 2008, ' Similarities and differences in lipidomics profiles among healthy monozygotic twin pairs. ', OMICS: A Journal of Integrative Biology, vol. 12, no. 1, pp. 17-31 . https://doi.org/10.1089/omi.2007.0048
Differences in genetic background and/or environmental exposure among individuals are expected to give rise to differences in measurable characteristics, or phenotypes. Consequently, genetic resemblance and similarities in environment should manifest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b39f64cd7923c28ff8bb217340121d91
http://www.tweelingenregister.org/nederlands/verslaggeving/NTR-publicaties_2008/Draisma_OMICS_2008.pdf
http://www.tweelingenregister.org/nederlands/verslaggeving/NTR-publicaties_2008/Draisma_OMICS_2008.pdf
Autor:
Aeilko H. Zwinderman, Ivana Bobeldijk, Theo H. Reijmers, Sandrin C. Bergheanu, Thomas Hankemeier, Anho Liem, Raymond Ramaker, J. Wouter Jukema, Jan van der Greef
Publikováno v:
Current medical research and opinion, 24(9), 2477-2487. Taylor and Francis Ltd.
Objective: Lipid profiling (lipidomics) may be useful in revealing detailed information with regard to the effects on lipid metabolism, the cardiovascular risk and to differentiate between therapies. The aims of the present study were to: (1) analyze
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f977ca79d324342d7825e965a3cef6ea
https://doi.org/10.1185/03007990802321709
https://doi.org/10.1185/03007990802321709
Autor:
Natalia Govorukhina, Frank Suits, Ate G.J. van der Zee, Peter Horvatovich, Theo H. Reijmers, Rainer Bischoff
Publikováno v:
Electrophoresis., 28(23), 4493-4505. Wiley-Blackwell
The discovery of biomarkers in easily accessible body fluids such as serum is one of the most challenging topics in proteomics requiring highly efficient separation and detection methodologies. Here, we present the application of a microfluidics-base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::180995832eb3b143a39ca96a09aa23fb
https://doi.org/10.1002/elps.200600719
https://doi.org/10.1002/elps.200600719