Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Theo Crawford"'
Autor:
Robertson, W. B.
Publikováno v:
BMJ: British Medical Journal, 1993 Aug . 307(6901), 441-441.
Externí odkaz:
https://www.jstor.org/stable/29720727
Autor:
Sina Jami, Jennifer R. Deuis, Tabea Klasfauseweh, Xiaoyang Cheng, Sergey Kurdyukov, Felicity Chung, Andrei L. Okorokov, Shengnan Li, Jiangtao Zhang, Ben Cristofori-Armstrong, Mathilde R. Israel, Robert J. Ju, Samuel D. Robinson, Peng Zhao, Lotten Ragnarsson, Åsa Andersson, Poanna Tran, Vanessa Schendel, Kirsten L. McMahon, Hue N. T. Tran, Yanni K.-Y. Chin, Yifei Zhu, Junyu Liu, Theo Crawford, Saipriyaa Purushothamvasan, Abdella M. Habib, David A. Andersson, Lachlan D. Rash, John N. Wood, Jing Zhao, Samantha J. Stehbens, Mehdi Mobli, Andreas Leffler, Daohua Jiang, James J. Cox, Stephen G. Waxman, Sulayman D. Dib-Hajj, G. Gregory Neely, Thomas Durek, Irina Vetter
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Voltage-gated sodium (NaV) channels are critical regulators of neuronal excitability and are targeted by many toxins that directly interact with the pore-forming α subunit, typically via extracellular loops of the voltage-sensing domains, o
Externí odkaz:
https://doaj.org/article/ef7fee6301d340c5b67edc494cc4b801
Autor:
Xinying Jia, Yanni K.-Y. Chin, Alan H. Zhang, Theo Crawford, Yifei Zhu, Nicholas L. Fletcher, Zihan Zhou, Brett R. Hamilton, Martin Stroet, Kristofer J. Thurecht, Mehdi Mobli
Publikováno v:
Communications Chemistry, Vol 6, Iss 1, Pp 1-10 (2023)
Head-to-tail macrocyclization of proteins and peptides can increase their structural stability, however, potential polymerization can lead to reduced yields. Here, the authors report the engineering of self-cyclizing ‘autocyclase’ proteins to gen
Externí odkaz:
https://doaj.org/article/e22b7329d2fa42c78900ee527f8a1241
Autor:
Michael J. Maxwell, Chris Thekkedam, Cedric Lamboley, Yanni K.-Y. Chin, Theo Crawford, Jennifer J. Smith, Junyu Liu, Xinying Jia, Irina Vetter, Derek R. Laver, Bradley S. Launikonis, Angela Dulhunty, Eivind A. B. Undheim, Mehdi Mobli
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Insect toxins with tandem repeats of neurotoxin domains have been found with enhanced receptor avidity. Here, the authors describe a bivalent toxin from remipede venom that targets ryanodine receptors, a rare target for animal venoms.
Externí odkaz:
https://doaj.org/article/ecfef30c1c5e4dc1ab651ec6f5d81576
Autor:
Theo Crawford, Nicholas Fletcher, Margaret Veitch, Jazmina L. Gonzalez Cruz, Nicola Pett, Ian Brereton, James W. Wells, Mehdi Mobli, Yasvir Tesiram
Publikováno v:
Frontiers in Medicine, Vol 6 (2019)
Squamous cell carcinoma (SCC) accounts for the majority of non-melanoma skin cancer related deaths, particularly in immunosuppressed persons. Identification of biomarkers that could be used to identify or treat SCC would be of significant benefit. Th
Externí odkaz:
https://doaj.org/article/91b2a7e110bd4c9d9241a85e7612b8e5
Autor:
Junyu Liu, Michael Maxwell, Thom Cuddihy, Theo Crawford, Madeline Bassetti, Cameron Hyde, Steve Peigneur, Jan Tytgat, Eivind A. B. Undheim, Mehdi Mobli
Receptor avidity through multivalency is a highly sought-after property of ligands. While readily available in nature in the form of bivalent antibodies, this property remains challenging to engineer in synthetic molecules. The discovery of several b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e320fe972cd30bb39e2e4b92746c2cad
https://lirias.kuleuven.be/handle/20.500.12942/715709
https://lirias.kuleuven.be/handle/20.500.12942/715709
Autor:
Junyu Liu, Michael Maxwell, Thom Cuddihy, Theo Crawford, Madeline Bassetti, Cameron Hyde, Eivind A. B. Undheim, Mehdi Mobli
Receptor avidity through multivalency is a highly sought-after property of ligands. While readily available in nature in the form of bivalent antibodies, this property remains challenging to engineer in synthetic molecules. The discovery of several b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::478ba6dff9f77f0adbcb1a770b7d155c
https://doi.org/10.1101/2022.01.17.476686
https://doi.org/10.1101/2022.01.17.476686
Autor:
Theo Crawford
Targeted molecular imaging is an emerging non-invasive tool for the identification and characterisation of cancers based on physiological and molecular properties. Molecular imaging is likely to play a significant role in the development and validati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87798b7a0a7448fd464eab7aeb45c551
https://doi.org/10.14264/uql.2019.579
https://doi.org/10.14264/uql.2019.579
Publikováno v:
Protein expression and purification. 161
We have developed a new ligation independent cloning (LIC) vector – pSrtA9, which can be utilized for one-step purification of recombinant proteins. The new LIC site in the pSrtA9 vector, hosts a DNA sequence centered on a SfoI restriction site and
Autor:
Theo. Crawford
Publikováno v:
Journal of the Institute of Brewing. 20:413-426