Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Thelma Y.-Y. Chan"'
Publikováno v:
Brain Research. 726:167-173
Fructose 1,6-bisphosphate (FBP) protects astrocytes from hypoxic injury in vitro. To determine whether FBP and citrate (inhibitors of phosphofructokinase) ameliorate hypoxia-induced injury to neurons and, if they do, whether the protective effects ar
Publikováno v:
Brain Research. 653:23-30
Damage to the cerebral endothelium from ischemia could exacerbate brain injury by altering vascular integrity, but little is known concerning the response of cerebral endothelial cells to hypoxia. To address this issue, cerebral capillary endothelial
Publikováno v:
Stroke. 24:855-863
Preexisting hyperglycemia exacerbates central nervous system injury after transient global and focal cerebral ischemia. Increased anaerobic metabolism with resultant lactic acidosis has been shown to cause the hyperglycemic, neuronal injury. The cont
Autor:
Thelma Y.-Y. Chan, Charles J. Epstein, Pak H. Chan, Liza Reola, Yibing Li, Jean-Christophe Copin
Publikováno v:
Journal of neurotrauma. 13(5)
The present work was designed to study the possible implication of apoptosis in ischemic neuronal death, a phenomenon that has been suggested to be involved in neurodegeneration following focal as well as global ischemia. In this study, mouse cortica
Autor:
Takeo Kondo, Charles J. Epstein, Shigeki Mikawa, E. Reola, Yibing Li, Juliette Gafni, Sharon Chen, Guo-Yuan Yang, Pak H. Chan, Glenn T. Gobbel, Thelma Y.-Y. Chan, Hiroyuki Kinouchi, Hideyuki Kamii, Jean-Christophe Copin, Elaine J. Carlson, Ting-Ting Huang
Publikováno v:
Journal of neurotrauma. 12(5)
A rapid increase in the need to explore the molecular basis of cellular function and injury in the central nervous system has led neuroscientists to employ transgenic mouse technology. The successful making of transgenic mice (Tg) overexpressing huma
Publikováno v:
Neurochemical research. 20(7)
The protective effects of fructose-1,6-biphosphate (FBP) during hypoxia/ischemia are thought to result from uptake and utilization of FBP as a substrate for glycolysis or from stimulation of glucose metabolism. To test these hypotheses, we measumed C
Autor:
Shigeki Imaizumi, Judith A. Kelleher, Sylvia F. Chen, Thelma Y.-Y. Chan, Pak H. Chan, George A. Gregory, Lillian Chu
Publikováno v:
Neurochemical Correlates of Cerebral Ischemia ISBN: 9781461364580
uring the past few decades, a large body of experimental data has accumulated indicating that the biological reduction of molecular oxygen could yield dangerously reactive free radical intermediates (Fridovich, 1986). In mammalian cells, various subc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c22a5b6799a4d324f18c1717670cf1ab
https://doi.org/10.1007/978-1-4615-3312-2_14
https://doi.org/10.1007/978-1-4615-3312-2_14