Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Thelma C. Madhok"'
Autor:
Donald P. Tashkin, Thelma C. Madhok, Lynn B. Gerald, Paul D. Scanlon, William C. Bailey, Michael S. Eichenhorn, Robert A. Wise
Publikováno v:
Chest. 124:57-62
Study objectives: Inhaled corticosteroids (ICS) are widely used in the treatment of COPD. One of the potential adverse effects of their use is the development of adrenal suppression. Our study aimed to determine the effects of ICS on adrenal function
Publikováno v:
Molecular Brain Research. 32:143-150
To understand the up-regulation of neuronal nicotinic cholinergic receptors (nAcChRs) that results from chronic in vivo treatment with nicotine, we studied the effect of nicotine on [3H]nicotine binding sites on PC 12 cells. PC 12 cells were grown in
Publikováno v:
Biochemical and Biophysical Research Communications. 182:1303-1308
Nicotinic cholinergic receptor proteins purified from rat brain by immunoaffinity chromatography were characterized using the anti-S3 polyclonal antibody vs. the anti-idiotypic monoclonal antibody 422F11 (generated against an antibody to nicotine). A
Nerve growth factor enhances [3H]nicotine binding to a nicotinic cholinergic receptor on PC 12 cells
Autor:
Burt M. Sharp, Thelma C. Madhok
Publikováno v:
Endocrinology. 130:825-830
Although nicotinic cholinergic agonists have functional effects on PC 12 cells, radioligand-binding sites have not been detected. We, therefore, studied PC 12 cells incubated in the presence of nerve growth factor (NGF) and determined that specific [
Autor:
Gail Weinmann, Michael S. Eichenhorn, Robert A. Wise, William C. Bailey, Paul D. Scanlon, Donald P. Tashkin, Melissa Skeans, John E. Connett, Richard E. Kanner, A. Sonia Buist, Paul C. Carpenter, Thelma C. Madhok
Publikováno v:
American journal of respiratory and critical care medicine. 170(12)
Inhaled glucocorticosteroids (ICS) are commonly prescribed for chronic obstructive pulmonary disease. No adverse effect on bone mineral density (BMD) has been proven. In a randomized double-blind, placebo-controlled trial at seven centers in North Am
Autor:
Michael S, Eichenhorn, Robert A, Wise, Thelma C, Madhok, Lynn B, Gerald, William C, Bailey, Donald P, Tashkin, Paul D, Scanlon
Publikováno v:
Chest. 124(1)
Inhaled corticosteroids (ICS) are widely used in the treatment of COPD. One of the potential adverse effects of their use is the development of adrenal suppression. Our study aimed to determine the effects of ICS on adrenal function over 3 years of u
Autor:
Benjamin S. Leung, Thelma C. Madhok
Publikováno v:
Journal of Steroid Biochemistry. 15:299-305
Progress to elucidate the mechanism of estrogen action in uterine tissues has been hampered because of the formidable task of receptor purification. This report describes our recent success in the purification of ERc from estrogen-primed rabbit uteru
Autor:
Elio Roti, Andrzej Bartke, A.G. Amador, D.N. Patel, Angelo Margutti, G. Robuschi, Angelo Gnudi, A. Audet, Theresa M. Siler-Khodr, Ellis R. Levin, R.K. Bhathena, Lewis E. Braverman, Burt M. Sharp, E.C. degli Uberti, Jan I.M. Drayer, Michael A. Weber, C.G.D. Brook, R. Pansini, Giorgio Trasforini, M.P. Hogan, Thelma C. Madhok, Guy R. Brisson, Roberto Tomatis, P. Matton, D. Pipeleers, T.A. Parkening, Benjamin S. Leung, J. Pellerin-Massicotte, M.H. Stallings, R. Stanhope, A. Hebert, M. Ledoux, S. Salvadori, F. Péronnet, E.J.G. Milroy, T.J. Collins
Publikováno v:
Hormone Research. 23:I-V
Autor:
Benjamin S. Leung, Thelma C. Madhok
Publikováno v:
Biochemical and Biophysical Research Communications. 115:988-994
This report presents the first application of ion-exchange high-performance liquid chromatography in the study of ER from the rabbit uterus. In the presence of sodium molybdate (20 mM), native ER was eluted as a sharp peak at 0.29 M NaCl by a linear
Autor:
Thelma C. Madhok, Benjamin S. Leung
Publikováno v:
Hormone research. 23(4)
Cytosolic (ERc) and nuclear (ERn) estrogen receptors prepared from rat uteri were characterized by size-exclusion and ion-exchange HPLC. The oligomeric ERc eluted as a single, sharp peak near the exclusion volume of the gel column; ERn eluted as a br