Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Thekkepat C Sandeep"'
Autor:
Ruth Andrew, Ken R. Smith, Robert Andrews, Natalie Z.M. Homer, Brian R. Walker, Thekkepat C. Sandeep
Publikováno v:
Diabetes. 54:872-879
11β-Hydroxysteroid dehydrogenase type 1 (11HSD1) regenerates cortisol from cortisone within adipose tissue and liver. 11HSD1 inhibitors may enhance insulin sensitivity in type 2 diabetes and be most efficacious in obesity when 11HSD1 is increased in
Autor:
June Noble, Alasdair M.J. MacLullich, Ian J. Deary, Brian R. Walker, Joyce L.W. Yau, Thekkepat C. Sandeep, Jonathan R. Seckl
Publikováno v:
Proceedings of the National Academy of Sciences. 101:6734-6739
In aging humans and rodents, inter-individual differences in cognitive function have been ascribed to variations in long-term glucocorticoid exposure. 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) regenerates the active glucocorticoid cortisol
Autor:
Richard Toshner, Kerry Walker, Donald Bain, Marion C. Devers, Thekkepat C Sandeep, Nicholas D Barwell
Publikováno v:
The British Journal of Diabetes & Vascular Disease. 12:186-188
Linezolid is a relatively novel oxazolidinone and its use is currently limited to secondary care in the UK. It is a reversible, non-selective monoamine oxidase inhibitor, but at the doses used for antibacterial therapy it does not exert an anti-depre
Autor:
C. A. McIntyre, Andrew I. Elliott, C H Buckley, Brent C. Williams, Patrick W. F. Hadoke, Gareth R. Jones, John A. McKnight, Thekkepat C. Sandeep, Gillian A. Gray, Robert Andrews, Brian R. Walker
Publikováno v:
British Journal of Pharmacology. 133:902-908
This investigation examined the hypothesis that release of K(+) accounts for EDHF activity by comparing relaxant responses produced by ACh and KCl in human subcutaneous resistance arteries. Resistance arteries (internal diameter 244+/-12 microm, n=48
Autor:
Thekkepat C Sandeep, Anthony D. Toft
Duration of radioprotective effects of antithyroid drug therapy is still not clear In this week's BMJ , Walter and colleagues1 present a systematic review and meta-analysis of randomised controlled trials of the effects of antithyroid drugs on treatm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bf0c8bf0ae835b894f40d24c576cfc5
https://europepmc.org/articles/PMC1819477/
https://europepmc.org/articles/PMC1819477/
Autor:
Vera Pompe-Kirn, Rebecca M. Reynolds, Ghislaine Scelo, Jon G. Jonasson, Erich V. Kliewer, Eero Pukkala, Carmen Martos, David H. Brewster, Mark W. J. Strachan, Paul Brennan, Paolo Boffetta, Elizabeth Tracey, Aage Anderson, Søren Friis, Jon Tonita, Kari Hemminki, Thekkepat C. Sandeep, Chia Kee-Seng, Mary L. McBride
Publikováno v:
The Journal of clinical endocrinology and metabolism. 91(5)
Context: Increasing incidence and improved prognosis of thyroid cancer have led to concern about the development of second primary cancers, especially after radioiodine treatment. Thyroid cancer can also arise as a second primary neoplasm after other
Autor:
Thekkepat C. Sandeep, Mark W. J. Strachan, Rebecca M. Reynolds, Jennifer Weir, David H. Brewster, Diane L. Stockton
Publikováno v:
Clinical endocrinology. 62(2)
Summary Objective The incidence of thyroid cancer is increasing in several countries. The aim was to investigate trends in the incidence and mortality of thyroid cancer in Scotland, where thyroid cancer is relatively uncommon, between 1960 and 2002.
Pathophysiology of modulation of local glucocorticoid levels by 11beta-hydroxysteroid dehydrogenases
Autor:
Brian R. Walker, Thekkepat C. Sandeep
Publikováno v:
Trends in endocrinology and metabolism: TEM. 12(10)
11beta-Hydroxysteroid dehydrogenases (11beta HSDs) are enzymes that catalyse the interconversion of active glucocorticoids (cortisol and corticosterone) into their inactive 11-keto products (cortisone and 11-deoxycorticosterone). Two isozymes have be
Autor:
Kerry Walker, Richard Toshner, Thekkepat C Sandeep, Marion Devers, Donald Bain, Nicholas Barwell
Publikováno v:
British Journal of Diabetes & Vascular Disease; Jul2012, Vol. 12 Issue 4, p186-188, 3p