Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Theile Jw"'
Autor:
Lihua He, Hong Dang, Scott H. Randell, Rhianna E. Lee, Minges Jt, Lisa C. Morton, Castle Na, Adam J. Kimple, Theile Jw, Michael R. Knowles, Catherine A. Lewis, Gallant Sc, Teresa M. Mascenik
With the approval of elexacaftor/tezacaftor/ivacaftor (trade name Trikafta), the vast majority of people with cystic fibrosis (CF) are eligible for CF transmembrane conductance regulator (CFTR) modulator therapy. Remaining individuals have premature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2de0779d2aa54a95f1251c245e574cd9
https://doi.org/10.1101/2021.09.28.462149
https://doi.org/10.1101/2021.09.28.462149
Autor:
Datta S; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University School of Medicine, Durham, North Carolina, USA.; Duke University School of Medicine, Department of Medicine, Division of Nephrology, Durham, North Carolina, USA., Antonio BM; OmniAb Inc., Durham, North Carolina, USA., Zahler NH; OmniAb Inc., Durham, North Carolina, USA., Theile JW; OmniAb Inc., Durham, North Carolina, USA., Krafte D; OmniAb Inc., Durham, North Carolina, USA., Zhang H; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University School of Medicine, Durham, North Carolina, USA.; Department of Medicine, Division of Cardiology, Duke University School of Medicine, Durham, North Carolina, USA., Rosenberg PB; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University School of Medicine, Durham, North Carolina, USA.; Department of Medicine, Division of Cardiology, Duke University School of Medicine, Durham, North Carolina, USA., Chaves AB; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University School of Medicine, Durham, North Carolina, USA., Muoio DM; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University School of Medicine, Durham, North Carolina, USA.; Department of Medicine, Division of Endocrinology, Metabolism, and Nutrition, Duke University School of Medicine, Durham, North Carolina, USA.; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina, USA., Zhang G; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University School of Medicine, Durham, North Carolina, USA.; Department of Medicine, Division of Endocrinology, Metabolism, and Nutrition, Duke University School of Medicine, Durham, North Carolina, USA., Silas D; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University School of Medicine, Durham, North Carolina, USA.; Duke University School of Medicine, Department of Medicine, Division of Nephrology, Durham, North Carolina, USA., Li G; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University School of Medicine, Durham, North Carolina, USA.; Duke University School of Medicine, Department of Medicine, Division of Nephrology, Durham, North Carolina, USA., Soldano K; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University School of Medicine, Durham, North Carolina, USA.; Duke University School of Medicine, Department of Medicine, Division of Nephrology, Durham, North Carolina, USA., Nystrom S; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University School of Medicine, Durham, North Carolina, USA.; Duke University School of Medicine, Department of Medicine, Division of Nephrology, Durham, North Carolina, USA., Ferreira D; Department of Pathology, Duke University Medical Center, Durham, North Carolina, USA., Miller SE; Department of Pathology, Duke University Medical Center, Durham, North Carolina, USA., Bain JR; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University School of Medicine, Durham, North Carolina, USA.; Department of Medicine, Division of Endocrinology, Metabolism, and Nutrition, Duke University School of Medicine, Durham, North Carolina, USA., Muehlbauer MJ; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University School of Medicine, Durham, North Carolina, USA., Ilkayeva O; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University School of Medicine, Durham, North Carolina, USA.; Department of Medicine, Division of Endocrinology, Metabolism, and Nutrition, Duke University School of Medicine, Durham, North Carolina, USA., Becker TC; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University School of Medicine, Durham, North Carolina, USA.; Department of Medicine, Division of Endocrinology, Metabolism, and Nutrition, Duke University School of Medicine, Durham, North Carolina, USA., Hohmeier HE; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University School of Medicine, Durham, North Carolina, USA.; Department of Medicine, Division of Endocrinology, Metabolism, and Nutrition, Duke University School of Medicine, Durham, North Carolina, USA., Newgard CB; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University School of Medicine, Durham, North Carolina, USA.; Department of Medicine, Division of Endocrinology, Metabolism, and Nutrition, Duke University School of Medicine, Durham, North Carolina, USA.; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina, USA., Olabisi OA; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University School of Medicine, Durham, North Carolina, USA.; Duke University School of Medicine, Department of Medicine, Division of Nephrology, Durham, North Carolina, USA.
Publikováno v:
The Journal of clinical investigation [J Clin Invest] 2024 Jan 16; Vol. 134 (5). Date of Electronic Publication: 2024 Jan 16.
Autor:
Lee RE; Marsico Lung Institute and Cystic Fibrosis Research Center.; Department of Cell Biology and Physiology., Lewis CA; Marsico Lung Institute and Cystic Fibrosis Research Center.; Department of Microbiology and Immunology, and., He L; Marsico Lung Institute and Cystic Fibrosis Research Center., Bulik-Sullivan EC; Marsico Lung Institute and Cystic Fibrosis Research Center.; Department of Cell Biology and Physiology., Gallant SC; Marsico Lung Institute and Cystic Fibrosis Research Center., Mascenik TM; Marsico Lung Institute and Cystic Fibrosis Research Center., Dang H; Marsico Lung Institute and Cystic Fibrosis Research Center., Cholon DM; Marsico Lung Institute and Cystic Fibrosis Research Center., Gentzsch M; Marsico Lung Institute and Cystic Fibrosis Research Center.; Department of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Morton LC; Marsico Lung Institute and Cystic Fibrosis Research Center., Minges JT; Marsico Lung Institute and Cystic Fibrosis Research Center., Theile JW; Icagen LLC, Durham, North Carolina, USA., Castle NA; Icagen LLC, Durham, North Carolina, USA., Knowles MR; Marsico Lung Institute and Cystic Fibrosis Research Center., Kimple AJ; Marsico Lung Institute and Cystic Fibrosis Research Center.; Department of Otolaryngology/Head and Neck Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Randell SH; Marsico Lung Institute and Cystic Fibrosis Research Center.; Department of Cell Biology and Physiology.
Publikováno v:
The Journal of clinical investigation [J Clin Invest] 2022 Sep 15; Vol. 132 (18). Date of Electronic Publication: 2022 Sep 15.
Autor:
Xiao Y; Biology department, School of Science, Indiana University Purdue University Indianapolis, Indianapolis, United States., Theile JW; Icagen LLC, 4222 Emperor Blvd #350, Durham, United States., Zybura A; Program in Medical Neuroscience, Paul and Carole Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, United States., Pan Y; Biology department, School of Science, Indiana University Purdue University Indianapolis, Indianapolis, United States., Lin Z; Icagen LLC, 4222 Emperor Blvd #350, Durham, United States., Cummins TR; Biology department, School of Science, Indiana University Purdue University Indianapolis, Indianapolis, United States.
Publikováno v:
ELife [Elife] 2022 Apr 20; Vol. 11. Date of Electronic Publication: 2022 Apr 20.
Autor:
Storer RI; Worldwide Medicinal Chemistry, Pfizer Ltd, The Portway, Granta Park, Cambridge CB21 6GS, UK. Electronic address: ian.storer@astrazeneca.com., Pike A; Pharmacokinetics, Dynamics and Metabolism, Pfizer Ltd, The Portway, Granta Park, Cambridge CB21 6GS, UK., Swain NA; Worldwide Medicinal Chemistry, Pfizer Ltd, The Portway, Granta Park, Cambridge CB21 6GS, UK., Alexandrou AJ; Electrophysiology, Pfizer Ltd, The Portway, Granta Park, Cambridge CB21 6GS, UK., Bechle BM; Worldwide Medicinal Chemistry, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Blakemore DC; Worldwide Medicinal Chemistry, Pfizer Ltd, The Portway, Granta Park, Cambridge CB21 6GS, UK., Brown AD; Worldwide Medicinal Chemistry, Pfizer Ltd, The Portway, Granta Park, Cambridge CB21 6GS, UK., Castle NA; Icagen Inc, 4222 Emperor Blvd #350, Durham, NC 27703, USA., Corbett MS; Worldwide Medicinal Chemistry, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Flanagan NJ; Pharmaceutical Sciences, Pfizer Ltd, The Portway, Granta Park, Cambridge CB21 6GS, UK., Fengas D; Peakdale Molecular, Ltd, Discovery Park House, Ramsgate Road, Sandwich, Kent CT13 9ND, UK., Johnson MS; Icagen Inc, 4222 Emperor Blvd #350, Durham, NC 27703, USA., Jones LH; Worldwide Medicinal Chemistry, Pfizer Inc, 610 Main Street, Cambridge, MA 02139, USA., Marron BE; Icagen Inc, 4222 Emperor Blvd #350, Durham, NC 27703, USA., Payne CE; Electrophysiology, Pfizer Ltd, The Portway, Granta Park, Cambridge CB21 6GS, UK., Printzenhoff D; Icagen Inc, 4222 Emperor Blvd #350, Durham, NC 27703, USA., Rawson DJ; Worldwide Medicinal Chemistry, Ramsgate Road, Sandwich, Kent CT13 9NJ, UK., Rose CR; Worldwide Medicinal Chemistry, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Ryckmans T; Worldwide Medicinal Chemistry, Ramsgate Road, Sandwich, Kent CT13 9NJ, UK., Sun J; Worldwide Medicinal Chemistry, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Theile JW; Icagen Inc, 4222 Emperor Blvd #350, Durham, NC 27703, USA., Torella R; Worldwide Medicinal Chemistry, Pfizer Ltd, The Portway, Granta Park, Cambridge CB21 6GS, UK., Tseng E; Pharmacokinetics, Dynamics and Metabolism, Pfizer Inc, Eastern Point Road, Groton, CT 06340, USA., Warmus JS; Worldwide Medicinal Chemistry, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA.
Publikováno v:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2017 Nov 01; Vol. 27 (21), pp. 4805-4811. Date of Electronic Publication: 2017 Sep 28.
Autor:
Theile JW; Neusentis US, Pfizer Global R&D, (currently Icagen, Inc.), Durham, North Carolina jtheile@icagen.com., Fuller MD; Neusentis US, Pfizer Global R&D, (currently Icagen, Inc.), Durham, North Carolina., Chapman ML; Neusentis US, Pfizer Global R&D, (currently Icagen, Inc.), Durham, North Carolina.
Publikováno v:
Molecular pharmacology [Mol Pharmacol] 2016 Nov; Vol. 90 (5), pp. 540-548. Date of Electronic Publication: 2016 Sep 01.
Autor:
Payne CE; Neusentis UK, Pfizer Global R&D, Cambridge, UK., Brown AR, Theile JW, Loucif AJ, Alexandrou AJ, Fuller MD, Mahoney JH, Antonio BM, Gerlach AC, Printzenhoff DM, Prime RL, Stockbridge G, Kirkup AJ, Bannon AW, England S, Chapman ML, Bagal S, Roeloffs R, Anand U, Anand P, Bungay PJ, Kemp M, Butt RP, Stevens EB
Publikováno v:
British journal of pharmacology [Br J Pharmacol] 2015 May; Vol. 172 (10), pp. 2654-70. Date of Electronic Publication: 2015 Apr 10.
Autor:
Theile JW; Department of Pharmacology and Toxicology, Stark Neurosciences Research Institute, Indiana University School of Medicine Indianapolis, IN, USA., Cummins TR
Publikováno v:
Frontiers in pharmacology [Front Pharmacol] 2011 Oct 04; Vol. 2, pp. 54. Date of Electronic Publication: 2011 Oct 04 (Print Publication: 2011).
Autor:
Theile JW; Department of Pharmacology and Toxicology, Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA. jontheile@yahoo.com, Cummins TR
Publikováno v:
Molecular pharmacology [Mol Pharmacol] 2011 Oct; Vol. 80 (4), pp. 724-34. Date of Electronic Publication: 2011 Jul 25.
Autor:
Koehler KR; Stark Neurosciences Research Institute., Tropel P, Theile JW, Kondo T, Cummins TR, Viville S, Hashino E
Publikováno v:
BMC neuroscience [BMC Neurosci] 2011 Aug 10; Vol. 12, pp. 82. Date of Electronic Publication: 2011 Aug 10.