Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Thea M. Friedman"'
Publikováno v:
Clinical Immunology ISBN: 9780702081651
Hematopoietic stem cell transplantation (HSCT) is an effective treatment for most hematological malignancies. Autologous HSCT targets malignancies in a dose-responsive manner, but regimen-related toxicities limit the intensity of the treatment regime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f076492b4035aff6808f6f8cdb30c06
https://doi.org/10.1016/b978-0-7020-8165-1.00092-7
https://doi.org/10.1016/b978-0-7020-8165-1.00092-7
Autor:
Robert Korngold, Johann Stein, Thea M. Friedman, Stacey L. Fanning, Stephanie A. Berger, Kristin Vazzana, Jenny Zilberberg
Publikováno v:
The Journal of Immunology. 190:447-457
The optimum use of allogeneic blood and marrow transplantation (BMT) as a curative therapy for hematological malignancies lies in the successful separation of mature donor T cells that are host reactive and induce graft-versus-host disease (GVHD) fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78cc4e07ec867b91ba066e4edb5f0f3a
https://doi.org/10.4049/jimmunol.1201641
https://doi.org/10.4049/jimmunol.1201641
Autor:
Chen Liu, Rebecca Evers, Pavan Reddy, Yaping Sun, Robert Korngold, Thea M. Friedman, Tomomi Toubai, Evelyn Nieves, Isao Tawara
Publikováno v:
Blood. 119:3844-3853
It is currently thought that acute GVHD cannot be elicited in the absence of Ag presentation by radiosensitive host hematopoietic-derived APCs after allogeneic BM transplantation. Because clinical data suggest that sex-mismatched H-Y Ags may be impor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38590ba90ffccdd1428d34a041c4a3b4
https://doi.org/10.1182/blood-2011-10-384057
https://doi.org/10.1182/blood-2011-10-384057
Publikováno v:
Biology of Blood and Marrow Transplantation. 17:330-340
Vaccination with irradiated autologous tumor cells, engineered to secrete granulocyte macrophage colony stimulating factor (GM-CSF) (GM-tumor), can generate potent anti-tumor effects when combined with autologous bone marrow transplantation (BMT). Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad5533aa1743365524b3271b120600b4
https://doi.org/10.1016/j.bbmt.2010.09.020
https://doi.org/10.1016/j.bbmt.2010.09.020
Autor:
William R. Drobyski, Dolores Grosso, Phyllis Flomenberg, John I. Wagner, Julie-An Talano, Robert Korngold, Andres Ferber, J. Brunner, Neal Flomenberg, Joanne Filicko-O'Hara, Bijoyesh Mookerjee, Carolyn A. Keever-Taylor, Thea M. Friedman, Irina Kakhniashvili
Publikováno v:
Biology of Blood and Marrow Transplantation. 15:1609-1619
Although allogeneic hematopoietic progenitor cell transplant (HPCT) is curative therapy for many disorders, it is associated with significant morbidity and mortality, which can be related to graft-versus-host disease (GVHD) and the immunosuppressive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c57505c749ef26249323bcdec31102d
https://doi.org/10.1016/j.bbmt.2009.08.020
https://doi.org/10.1016/j.bbmt.2009.08.020
Publikováno v:
The Journal of Immunology. 183:4261-4272
The MHC-matched, minor histocompatibility Ag (miHA)-mismatched B10.BR→CBA strain combination has been used to elucidate the immunobiology of graft-vs-host disease (GVHD) following allogeneic bone marrow transplantation. Studies conducted in the 198
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::305c38882ccd9ea13281d9185d1fa20e
https://doi.org/10.4049/jimmunol.0900971
https://doi.org/10.4049/jimmunol.0900971
Autor:
Robert Korngold, Michele L. Donato, Jenny Zilberberg, Neal Flomenberg, Thea M. Friedman, Scott D. Rowley, Joanne Filicko-O'Hara, Stephanie A. Berger, Kira Goldgirsh
Publikováno v:
Blood. 112:3517-3525
Following allogeneic blood and marrow transplantation (BMT), mature donor T cells can enhance engraftment, counteract opportunistic infections, and mount graft-versus-tumor (GVT) responses, but at the risk of developing graft-versus-host disease (GVH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2de6ff1e5c25d1e101fcb32ad2c82c8c
https://doi.org/10.1182/blood-2008-03-145391
https://doi.org/10.1182/blood-2008-03-145391
Publikováno v:
The Journal of Immunology. 180:5352-5359
Lethal graft-vs-host disease (GVHD) can be induced between MHC-matched murine strains expressing multiple minor histocompatibility Ag differences. In the B6–>BALB.B model, both CD4+ and CD8+ donor T cells can mediate lethal GVHD, whereas in the B6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ed21b0a85884de36ed77bc5ecf6b4b5
https://doi.org/10.4049/jimmunol.180.8.5352
https://doi.org/10.4049/jimmunol.180.8.5352
Autor:
George F. Murphy, Robert Korngold, Thea M. Friedman, Sabina Signoretti, Diana Whitaker-Menezes, Qian Zhan
Publikováno v:
Journal of Investigative Dermatology. 127:106-115
The normal gene expression profile of rete-tip keratinocytes targeted in human graft-versus-host disease (GVHD) remains unexplored. Murine lingual epithelium, unlike murine skin, consists of a basal layer that resembles human cutaneous rete ridges an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55a53b508722555e4116e8e304290c94
https://doi.org/10.1038/sj.jid.5700583
https://doi.org/10.1038/sj.jid.5700583
Publikováno v:
Biology of Blood and Marrow Transplantation. 12(8):818-827
Although CD4(+) T cells can have an important role in mediating lethal graft-versus-host disease (GVHD) directed to multiple minor histocompatibility antigens (miHA) after bone marrow transplantation, their precise characterization and effector funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fb4ea94669f7965bf76f2cd9dd87717