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pro vyhledávání: '"Thea Kaestel"'
Autor:
Maria Pedersen, Maria Bjerg, Salli Nielsen, Martha Kampp Nøhr, Stephanie Müller, René Holm, Nithiya Ulaganathan, Carsten Uhd Nielsen, Thea Kaestel, Krestine Lundgaard Carlsen
Publikováno v:
Nielsen, C U, Pedersen, M, Muller, S, Kaestel, T, Bjerg, M, Ulaganathan, N, Nielsen, S, Carlsen, K L, Nohr, M K & Holm, R 2021, ' Inhibitory Effects of 17-alpha-Ethinyl-Estradiol and 17-beta-Estradiol on Transport Via the Intestinal Proton-Coupled Amino Acid Transporter (PAT1) Investigated In Vitro and In Vivo ', Journal of Pharmaceutical Sciences, vol. 110, no. 1, pp. 354-364 . https://doi.org/10.1016/j.xphs.2020.08.010
Nielsen, C U, Pedersen, M, Müller, S, Kæstel, T, Bjerg, M, Ulaganathan, N, Nielsen, S, Lundgaard Carlsen, K, Nøhr, M K & Holm, R 2021, ' Inhibitory effects of 17-α-ethinyl-estradiol and 17-β-estradiol on transport via the intestinal proton-coupled amino acid transporter (PAT1) investigated In vitro and in vivo ', Journal of Pharmaceutical Sciences, vol. 110, no. 1, pp. 354-364 . https://doi.org/10.1016/j.xphs.2020.08.010
Nielsen, C U, Pedersen, M, Müller, S, Kæstel, T, Bjerg, M, Ulaganathan, N, Nielsen, S, Lundgaard Carlsen, K, Nøhr, M K & Holm, R 2021, ' Inhibitory effects of 17-α-ethinyl-estradiol and 17-β-estradiol on transport via the intestinal proton-coupled amino acid transporter (PAT1) investigated In vitro and in vivo ', Journal of Pharmaceutical Sciences, vol. 110, no. 1, pp. 354-364 . https://doi.org/10.1016/j.xphs.2020.08.010
The proton-coupled amino acid transporter, PAT1, is known to be responsible for intestinal absorption drug substances such as gaboxadol and vigabatrin. The aim of the present study was to investigate, if 17-alpha-ethinyl-estradiol (E-E2) and 17-beta-