Zobrazeno 1 - 10
of 1 808
pro vyhledávání: '"The Spongiform Encephalopathies"'
Autor:
Hasier Eraña, Carlos M. Díaz-Domínguez, Jorge M. Charco, Enric Vidal, Ezequiel González-Miranda, Miguel A. Pérez-Castro, Patricia Piñeiro, Rafael López-Moreno, Cristina Sampedro-Torres-Quevedo, Leire Fernández-Veiga, Juan Tasis-Galarza, Nuria L. Lorenzo, Aileen Santini-Santiago, Melisa Lázaro, Sandra García-Martínez, Nuno Gonçalves-Anjo, Maitena San-Juan-Ansoleaga, Josu Galarza-Ahumada, Eva Fernández-Muñoz, Samanta Giler, Mikel Valle, Glenn C. Telling, Mariví Geijó, Jesús R. Requena, Joaquín Castilla
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-30 (2023)
Abstract Among transmissible spongiform encephalopathies or prion diseases affecting humans, sporadic forms such as sporadic Creutzfeldt–Jakob disease are the vast majority. Unlike genetic or acquired forms of the disease, these idiopathic forms oc
Externí odkaz:
https://doaj.org/article/63c13fcaea6249e3a04b3b8cea76b3ad
Autor:
Andreu Matamoros-Angles, Behnam Mohammadi, Feizhi Song, Mohsin Shafiq, Santra Brenna, Berta Puig, Markus Glatzel, Hermann C Altmeppen
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 9, Pp 1869-1875 (2023)
In the last decades, the role of the prion protein (PrP) in neurodegenerative diseases has been intensively investigated, initially in prion diseases of humans (e.g., Creutzfeldt-Jakob disease) and animals (e.g., scrapie in sheep, chronic wasting dis
Externí odkaz:
https://doaj.org/article/f326dae2cbf2448ba7826c92752c6b8d
Publikováno v:
Prion, Vol 16, Iss 1, Pp 265-294 (2022)
ABSTRACTPrion diseases are a group of incurable zoonotic neurodegenerative diseases (NDDs) in humans and other animals caused by the prion proteins. The abnormal folding and aggregation of the soluble cellular prion proteins (PrPC) into scrapie isofo
Externí odkaz:
https://doaj.org/article/4effbb93cc2a4bb8a8112bf91c9e395d
Publikováno v:
Open Veterinary Journal, Vol 11, Iss 4, Pp 707-723 (2021)
Animal prion diseases are a group of neurodegenerative, transmissible, and fatal disorders that affect several animal species. The causative agent, prion, is a misfolded isoform of normal cellular prion protein, which is found in cells with higher co
Externí odkaz:
https://doaj.org/article/23d3fe7b306046eda22fd09dfdbf7d11
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-10 (2021)
Abstract In sporadic Creutzfeldt–Jakob disease (sCJD), the pathological changes appear to be restricted to the central nervous system. Only involvement of the trigeminal ganglion is widely accepted. The present study systematically examined the inv
Externí odkaz:
https://doaj.org/article/d293f9a2efb24f738a2a263a001ade82
Publikováno v:
Emerging Infectious Diseases, Vol 27, Iss 12, Pp 3156-3158 (2021)
Chronic wasting disease (CWD) is a fatal prion disease of cervids. We examined host range of CWD by oronasally inoculating Suffolk sheep with brain homogenate from a CWD-positive white-tailed deer. Sixty months after inoculation, 1/7 sheep had immuno
Externí odkaz:
https://doaj.org/article/11f9a890ba1346c78cc564c2c4ba0537
Autor:
Alba Marín-Moreno, Alvina Huor, Juan Carlos Espinosa, Jean Yves Douet, Patricia Aguilar-Calvo, Naima Aron, Juan Píquer, Sévérine Lugan, Patricia Lorenzo, Cecile Tillier, Hervé Cassard, Olivier Andreoletti, Juan María Torres
Publikováno v:
Emerging Infectious Diseases, Vol 26, Iss 6, Pp 1130-1139 (2020)
Classical bovine spongiform encephalopathy (BSE) is the only zoonotic prion disease described to date. Although the zoonotic potential of atypical BSE prions have been partially studied, an extensive analysis is still needed. We conducted a systemati
Externí odkaz:
https://doaj.org/article/2091a3c7a1dd48f483f428a04744bb7a
Autor:
T. E. Popova, A. A. Tappakhov, T. K. Davydova, T. Ya. Nikolaeva, Yu. I. Khabarova, M. A. Varlamova, L. T. Okoneshinova
Publikováno v:
Неврология, нейропсихиатрия, психосоматика, Vol 12, Iss 2, Pp 86-91 (2020)
Creutzfeldt–Jakob disease (CJD) is a rare neurodegenerative disease caused by the accumulation of the pathological isoform of prion protein. The classic clinical presentation of CJD is characterized by rapidly progressive dementia, ataxia, myoclonu
Externí odkaz:
https://doaj.org/article/801316aa23d948f58cbc0c19c0cf3cc8
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Immortalized uninfected septal (SEP) neurons proliferate but after physiological mitotic arrest they express differentiated neuronal characteristics including enhanced cell-to-cell membrane contacts and ≥ 8 fold increases in host prion protein (PrP
Externí odkaz:
https://doaj.org/article/8684581711d649aa877ffeb2f921b810
Autor:
Laura Tejedor-Romero, Teresa López-Cuadrado, Javier Almazán-Isla, Miguel Calero, Fernando J. García López, Jesús de Pedro-Cuesta
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2022)
BackgroundHuman transmissible spongiform encephalopathies (TSEs) are a group of fatal neurodegenerative disorders of short duration. There are few studies on TSE survival. This study sought to analyze the survival and related factors of a TSE patient
Externí odkaz:
https://doaj.org/article/c232f454131d45a9848dcb85ec52092a