Polymorphisms of matrix metalloproteinase-7 and -9 are associated with oral tongue squamous cell carcinoma

Autor: George João Ferreira do NASCIMENTO, Leorik Pereira da SILVA, Felipe Rodrigues de MATOS, Thayse Azevedo da SILVA, Silvia Regina Batistuzzo de MEDEIROS, Lélia Batista de SOUZA, Roseana de Almeida FREITAS

Publikováno v: Brazilian Oral Research, Vol 35 (2020)

Abstract Matrix degradation is an important event in the progression, invasion and metastasis of malignant head and neck lesions. Imbalances, mutations and polymorphisms of MMPs and their inhibitors are observed in several cancer subtypes. The aim of

Externí odkaz: https://doaj.org/article/d48267ec5d0a4623a4fe195927993723

Helicobacter pylori genotype and polymorphisms in DNA repair enzymes: Where do they correlate in gastric cancer?

Autor: Márcia Valéria Pitombeira Ferreira, Isabelle Joyce de Lima Silva-Fernandes, Thayse Azevedo da Silva, Lucymara Fassarella Agnez-Lima, Silvia Helena Barem Rabenhorst

Publikováno v: Journal of Surgical Oncology. 106:448-455

Background and Objectives One of the mechanisms proposed by which H. pylori causes gastric cancer (GC) is through DNA damage due to chronic inflammation. Genomic integrity is guaranteed by repair enzymes such as APE-1, OGG-1, and PARP-1. Host genetic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1932d319389b915e50231273cb7ce3e9
https://doi.org/10.1002/jso.23077

Polymorphisms in DNA Repair Gene XRCC1 (Arg194Trp) and (Arg399Gln) and their Role in the susceptibility of Bacterial Meningitis

Autor: Leonam Gomes Coutinho, Stephen L. Leib, Daniele Maria Lopes Pinheiro, Fabrícia Lima Fontes, Thayse Azevedo da Silva, Lucymara Fassarella Agnez-Lima, Ana Helena Sales de Oliveira

Publikováno v: Journal of Meningitis.

Meningitis is a contagious infectious disease with high rates of mortality. Most pathogenic microbes in humans have the ability to cause bacterial meningitis. However, the most common pathogens are Streptococcus pneumoniae, Neisseria meningitidis and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ff1793c7bf50a4590b7ac920b7d6baea
https://doi.org/10.4172/2572-2050.1000105

Association of kynurenine aminotransferase II gene C401T polymorphism with immune response in patients with meningitis

Autor: Stephen L. Leib, Fladjule Rejane Soares de Souza, Leonam Gomes Coutinho, Lucymara Fassarella Agnez-Lima, Fabrícia Lima Fontes, Thayse Azevedo da Silva

Publikováno v: BMC Medical Genetics, Vol 12, Iss 1, p 51 (2011)
BMC Medical Genetics
de Souza, Fladjule Rejane Soares; Fontes, Fabrícia Lima; da Silva, Thayse Azevedo; Coutinho, Leonam Gomes; Leib, Stephen L.; Agnez-Lima, Lucymara Fassarella (2011). Association of kynurenine aminotransferase II gene C401T polymorphism with immune response in patients with meningitis. BMC medical genetics, 12(51), p. 51. London: BioMed Central 10.1186/1471-2350-12-51

Background The kynurenine (KYN) pathway has been shown to be altered in several diseases which compromise the central nervous system (CNS) including infectious diseases such as bacterial meningitis (BM). The aim of this study was to assess single nuc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d539bc5e1a2a4c5676f76fdf5e064f37
http://www.biomedcentral.com/1471-2350/12/51