Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Thayana A. Cruz"'
Autor:
Thayana A. Cruz, Nicholas R. Larson, Yangjie Wei, Natalia Subelzu, Yaqi Wu, Christian Schöneich, Leda R. Castilho, Charles Russell Middaugh
Publikováno v:
Biologics, Vol 4, Iss 3, Pp 294-313 (2024)
During early development of biopharmaceuticals, suboptimal producing clones and production conditions can result in limited quantities of high-purity products. Here we describe a systematic approach, which requires minimal amounts of protein (~10 mg)
Externí odkaz:
https://doaj.org/article/4ce9af17cf744b2d9eec9bbc902b6693
Autor:
Nicholas R, Larson, Yangjie, Wei, Thayana Araújo, Cruz, Reza, Esfandiary, Cavan K, Kalonia, M Laird, Forrest, C Russell, Middaugh
Publikováno v:
Journal of Pharmaceutical Sciences. 112:680-690
Liquid-liquid phase separation is a phenomenon within biology whereby proteins can separate into dense and more dilute phases with distinct properties. Three antibodies that undergo liquid-liquid phase separation were characterized in the protein-ric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eb964b48d028310f96720b71a6f27ac
https://doi.org/10.1016/j.xphs.2022.10.017
https://doi.org/10.1016/j.xphs.2022.10.017
Publikováno v:
Biotechnology letters. 42(12)
To compare different approaches for the expression of an anti-PCSK9 biosimilar monoclonal antibody (mAb) in CHO cells using IRES-mediated tricistronic plasmid vectors combining different signal peptides, IRES elements and selection markers. Transient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa75f5c6d57105387b3669e381fab730
https://pubmed.ncbi.nlm.nih.gov/32676798
https://pubmed.ncbi.nlm.nih.gov/32676798
Autor:
Thayana A. Cruz, Rimenys J. Carvalho
Publikováno v:
Methods in Molecular Biology ISBN: 9781493973118
High-throughput screening (HTS) systems have emerged as important tools to provide fast and low cost evaluation of several conditions at once since it requires small quantities of material and sample volumes. These characteristics are extremely valua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f868922033058c5395442a47d8c6679
https://doi.org/10.1007/978-1-4939-7312-5_17
https://doi.org/10.1007/978-1-4939-7312-5_17
Autor:
Rimenys J, Carvalho, Thayana A, Cruz
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1674
High-throughput screening (HTS) systems have emerged as important tools to provide fast and low cost evaluation of several conditions at once since it requires small quantities of material and sample volumes. These characteristics are extremely valua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1b6e9dcdc1e5ba7eaaa08119ae274d02
https://pubmed.ncbi.nlm.nih.gov/28921440
https://pubmed.ncbi.nlm.nih.gov/28921440
Publikováno v:
Biotechnology progress. 33(4)
The pressures to efficiently produce complex biopharmaceuticals at reduced costs are driving the development of novel techniques, such as in downstream processing with straight-through processing (STP). This method involves directly and sequentially
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::173cbed480d0822d32cc7b2bd3512b55
https://pubmed.ncbi.nlm.nih.gov/28556541
https://pubmed.ncbi.nlm.nih.gov/28556541
Publikováno v:
Anais do Simpósio Nacional de Bioprocessos.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73f4553e604b3204703f42935f00c8e2
https://doi.org/10.17648/sinaferm-2015-33381
https://doi.org/10.17648/sinaferm-2015-33381
Autor:
Gabriela Veras de Moraes, Thayana A. Cruz, T.C. Paredes-Santos, Márcia Attias, Karla Dias Cruz, Wanderley de Souza
Publikováno v:
BioMed Research International, Vol 2014 (2014)
BioMed Research International
BioMed Research International
The intracellular parasiteToxoplasma gondiican penetrate any warm-blooded animal cell. Conserved molecular assemblies of host cell plasma membranes should be involved in the parasite-host cell recognition. Lipid rafts are well-conserved membrane micr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b08dba18c0c57196d1510d36c399ce66
https://doaj.org/article/c24c49ea91574b258781379c5aae71ae
https://doaj.org/article/c24c49ea91574b258781379c5aae71ae