Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Thaya Ramaesh"'
Publikováno v:
Experimental Eye Research. 89:263-273
Mutations in PAX6/Pax6 lead to a variety of ocular anomalies in humans and mice. The aim of the study was to characterise the ocular abnormalities caused by the missense Pax6(Leca4) mutation and compare them to published observations on Pax6 alleles
Autor:
Simon A. Chanas, J. Martin Collinson, John D. West, Kanna Ramaesh, Thaya Ramaesh, Baljean Dhillon
Publikováno v:
Experimental Eye Research. 81:224-235
Heterozygosity for a PAX6 deficiency (PAX6+/−) results in low levels of the PAX6 transcription factor and causes aniridia. Corneal changes in aniridia-related keratopathy (ARK) include peripheral pannus and epithelial abnormalities, which eventuall
Autor:
Thaya Ramaesh, Robert E. Hill, J. Martin Collinson, Seong-Seng Tan, Margaret A. Keighren, Jean H. Flockhart, Baljean Dhillon, Lucy Morris, John D West, Kanna Ramaesh, Alasdair I. Reid
Publikováno v:
Developmental Dynamics. 224:432-440
Patterns of growth and cell movement in the developing and adult corneal epithelium were investigated by analysing clonal patches of LacZ-expressing cells in chimeric and X-inactivation mosaic mice. It was found that cell proliferation throughout the
Autor:
J. Martin Collinson, Simon A. Chanas, John D West, Natalie Dora, Thaya Ramaesh, Robert E. Hill, Dirk A. Kleinjan
Publikováno v:
Chanas, S A, Collinson, J M, Ramaesh, T, Dora, N, Kleinjan, D A, Hill, B & West, J D 2009, ' Effects of Elevated Pax6 Expression and Genetic Background on Mouse Eye Development ', Investigative Ophthalmology & Visual Science, vol. 50, no. 9, pp. 4045-4059 . https://doi.org/10.1167/iovs.07-1630
The eye develops from three major sources of cells. The surface ectoderm of the head produces the lens and the corneal, limbal, and conjunctival epithelia. The neuroectoderm produces the neural retina and retinal pigment epithelium (RPE), and extensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51560f6a83bf5c1e0c80209ec29684ea
https://europepmc.org/articles/PMC2763115/
https://europepmc.org/articles/PMC2763115/
Publikováno v:
Mort, R L, Ramaesh, T, Kleinjan, D A, Morley, S D & West, J D 2009, ' Mosaic analysis of stem cell function and wound healing in the mouse corneal epithelium ', BMC Developmental Biology, vol. 9, pp. 4 . https://doi.org/10.1186/1471-213X-9-4
BMC Developmental Biology, Vol 9, Iss 1, p 4 (2009)
BMC Developmental Biology
BMC Developmental Biology, Vol 9, Iss 1, p 4 (2009)
BMC Developmental Biology
Background The mouse corneal epithelium is a continuously renewing 5–6 cell thick protective layer covering the corneal surface, which regenerates rapidly when injured. It is maintained by peripherally located limbal stem cells (LSCs) that produce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df8811b89da9921d8e7d5251bc1ffd09
https://www.pure.ed.ac.uk/ws/files/7746586/Mosaic_analysis_of_stem_cell_function_and_wound_healing_in_the_mouse_corneal_epithelium.pdf
https://www.pure.ed.ac.uk/ws/files/7746586/Mosaic_analysis_of_stem_cell_function_and_wound_healing_in_the_mouse_corneal_epithelium.pdf
Autor:
Thaya Ramaesh, Jonathan Bard
Three-dimensional reconstruction and BrdU incorporation have been used to quantify the development and growth of the mouse mandible and to analyse its relationship to Meckel's cartilage and the molar teeth. The mandible anlage is first histologically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8dbcbc64d3a9557c86f756d2185d5b2
https://europepmc.org/articles/PMC1571157/
https://europepmc.org/articles/PMC1571157/
Autor:
J. Martin Collinson, Matthew H. Kaufman, Baljean Dhillon, Kanna Ramaesh, Thaya Ramaesh, John D. West
Publikováno v:
Investigative ophthalmologyvisual science. 44(5)
Purpose To investigate corneal abnormalities in heterozygous Pax6(+/Sey-Neu) (Pax6(+/-), small eye) mice and compare them with aniridia-related keratopathy in PAX6(+/-) patients. Methods Fetal and postnatal corneal histopathology, adult corneal thick