Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Thati, Madhusudhan"'
Autor:
Xiaodan Zhong, Tao Wang, Yang Xie, Mengwen Wang, Wenjun Zhang, Lei Dai, Jinsheng Lai, Xiang Nie, Xingwei He, Thati Madhusudhan, Hesong Zeng, Hongjie Wang
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Aims: The pathogenesis of diabetic cardiomyopathy (DCM) is complex and the detailed mechanism remains unclear. Coagulation protease activated Protein C (aPC) has been reported to have a protective effect in diabetic microvascular disease. Here, we in
Externí odkaz:
https://doaj.org/article/2b5c8fd2f7be485cb4d0b8368771eac2
Autor:
Srikanth Karnati, Michael Seimetz, Florian Kleefeldt, Avinash Sonawane, Thati Madhusudhan, Akash Bachhuka, Djuro Kosanovic, Norbert Weissmann, Karsten Krüger, Süleyman Ergün
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide and encompasses chronic bronchitis and emphysema. It has been shown that vascular wall remodeling and pulmonary hypertension (PH) can occur not only in
Externí odkaz:
https://doaj.org/article/60f6ccf18c3e4274823d8e37183430f2
Publikováno v:
Pharmaceuticals, Vol 15, Iss 4, p 401 (2022)
A growing body of scientific evidence indicates that protein homeostasis, also designated as proteostasis, is causatively linked to chronic diabetic nephropathy (DN). Experimental studies have demonstrated that the insulin signaling in podocytes main
Externí odkaz:
https://doaj.org/article/969ddd0e1e0d4abf9c61c902588d7762
Akademický článek
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Autor:
Tao Wang, Yujian Liu, Wenjun Zhang, Mengwen Wang, Hongjie Wang, Xingwei He, Wei Dong, Xiaodan Zhong, Thati Madhusudhan, Yang Xie, Hesong Zeng, Lei Dai, Wanjun Liu, Jinhua Wu
Publikováno v:
International Journal of Biological Sciences
Background: Chronic diabetes accelerates vascular dysfunction often resulting in cardiomyopathy but underlying mechanisms remains unclear. Recent studies have shown that the deregulated unfolded protein response (UPR) dependent on highly conserved IR
Akademický článek
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Autor:
Silke Zimmermann, Alireza R. Rezaie, Marcus J. Moeller, Sumra Nazir, Liliana Schaefer, Shruthi Krishnan, Shrey Kohli, Ihsan Gadi, Wei Dong, Sanchita Ghosh, Rajiv Rana, Wolfram Ruf, Dheerendra Gupta, Thati Madhusudhan, Jochen Reiser, Stoyan Stoyanov, Hongjie Wang, Jinyang Zeng-Brouwers, Charles T. Esmon, Ronald Biemann, Berend Isermann, Moh'd Mohanad Al-Dabet, Ahmed Elwakiel, Akash Mathew
Publikováno v:
J Am Soc Nephrol
Journal of the American Society of Nephrology 31(8), 1762-1780 (2020). doi:10.1681/ASN.2019111163
Journal of the American Society of Nephrology 31(8), 1762-1780 (2020). doi:10.1681/ASN.2019111163
BACKGROUND: Diabetic nephropathy (dNP), now the leading cause of ESKD, lacks efficient therapies. Coagulation protease–dependent signaling modulates dNP, in part via the G protein–coupled, protease-activated receptors (PARs). Specifically, the cy
Autor:
Shahzad, Khurrum, Thati, Madhusudhan, Wang, Hongjie, Kashif, Muhammed, Wolter, Juliane, Ranjan, Satish, He, Tao, Zhou, Qianxing, Blessing, Erwin, Bierhaus, Angelika, Nawroth, Peter P., Isermann, Berend
Publikováno v:
In Atherosclerosis November 2011 219(1):74-83
Autor:
Wolfram Ruf, Thati Madhusudhan
Publikováno v:
Hämostaseologie. 39:164-172
Nutrient excess in obesity drives metabolic reprogramming in multiple tissues involving extensive interorgan and intercellular crosstalk. Experimental and clinical studies show that prolonged nutrient excess often compromises metabolic adaptation pro
Autor:
Xiaodan Zhong, Tao Wang, Wenjun Zhang, Mengwen Wang, Yang Xie, Lei Dai, Xingwei He, Thati Madhusudhan, Hesong Zeng, Hongjie Wang
Publikováno v:
Journal of Biological Chemistry. 298:101989
Diabetic cardiomyopathy (DCM) is a major complication of diabetes, but its underlying mechanisms still remain unclear. The multifunctional protein Y-box binding protein-1 (YB-1) plays an important role in cardiac pathogenesis by regulating cardiac ap