Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Tharvesh Moideen Liyakat Ali"'
Autor:
Miguel Casanova, Madeleine Moscatelli, Louis Édouard Chauvière, Christophe Huret, Julia Samson, Tharvesh Moideen Liyakat Ali, Olga Rosspopoff, Claire Rougeulle
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
XACT is a primate-specific TE-derived lncRNA that coats active X chromosomes in pluripotent cells and may contribute to species-specific regulation of X chromosome inactivation. Here, the authors investigate TEs associated with the XACT locus and ide
Externí odkaz:
https://doaj.org/article/f9c5f63441214330bad8768b8203536f
Autor:
Maxim Nekrasov, Jonas Paulsen, Erwan Delbarre, David J. Tremethick, Tharvesh Moideen Liyakat Ali, Marie-Odile Baudement, Sebastian Kurscheid, Philippe Collas
Publikováno v:
Nature Genetics. 51:835-843
Genomic information is selectively used to direct spatial and temporal gene expression during differentiation. Interactions between topologically associating domains (TADs) and between chromatin and the nuclear lamina organize and position chromosome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1a3ee379aa78b0c1a9453e5eec1a795
https://doi.org/10.1038/s41588-019-0392-0
https://doi.org/10.1038/s41588-019-0392-0
Publikováno v:
Nucleus
Nucleus, Vol 10, Iss 1, Pp 7-20 (2019)
Nucleus, Vol 10, Iss 1, Pp 7-20 (2019)
Immunosuppressive drugs such as cyclosporin A (CsA) can elicit hepatotoxicity by affecting gene expression. Here, we address the link between CsA and large-scale chromatin organization in HepG2 hepatocarcinoma cells. We show the existence of lamina-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2f017336db44ccb683ab0bbf0b64932
http://europepmc.org/articles/PMC6363278
http://europepmc.org/articles/PMC6363278
Publikováno v:
BMC Genomics
BMC Genomics, Vol 22, Iss 1, Pp 1-11 (2021)
BMC Genomics, Vol 22, Iss 1, Pp 1-11 (2021)
Background Mechanisms underlying genome 3D organization and domain formation in the mammalian nucleus are not completely understood. Multiple processes such as transcriptional compartmentalization, DNA loop extrusion and interactions with the nuclear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78ca15c47d135f072ea2d12e882d6f5a
https://pubmed.ncbi.nlm.nih.gov/34217222
https://pubmed.ncbi.nlm.nih.gov/34217222
Publikováno v:
Nature Protocols. 13:1137-1152
Chrom3D is a computational platform for 3D genome modeling that simulates the spatial positioning of chromosome domains relative to each other and relative to the nuclear periphery. In Chrom3D, chromosomes are modeled as chains of contiguous beads, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b3e63cd2e5323640883e687647bc89e
https://doi.org/10.1038/nprot.2018.009
https://doi.org/10.1038/nprot.2018.009
Publikováno v:
Frontiers in Genetics
Frontiers in Genetics, Vol 10 (2019)
Frontiers in Genetics, Vol 10 (2019)
The mammalian genome is intricately folded in a three-dimensional topology believed to be important for the orchestration of gene expression regulating development, differentiation and tissue homeostasis. Important features of spatial genome conforma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::329d9761cae75ec8891ff7480eac2e73
http://europepmc.org/articles/PMC6593077
http://europepmc.org/articles/PMC6593077
Enlightening the contribution of the dark matter to the X chromosome inactivation process in mammals
Publikováno v:
Seminars in Cell & Developmental Biology
Seminars in Cell & Developmental Biology, 2016, 56, pp.48-57. ⟨10.1016/j.semcdb.2016.05.003⟩
Seminars in Cell & Developmental Biology, 2016, 56, pp.48-57. ⟨10.1016/j.semcdb.2016.05.003⟩
X-chromosome inactivation (XCI) in mammals represents an exceptional example of transcriptional co-regulation occurring at the level of an entire chromosome. XCI is considered as a means to compensate for gene dosage imbalance between sexes, yet the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbaaad96dc990a3929238a1e89cb89e7
https://doi.org/10.1016/j.semcdb.2016.05.003
https://doi.org/10.1016/j.semcdb.2016.05.003