Raised Plasma Neurofilament Light Protein Levels After Rewarming Are Associated With Adverse Neurodevelopmental Outcomes in Newborns After Therapeutic Hypothermia

Autor: Divyen K. Shah, Ping K. Yip, Akif Barlas, Pavithira Tharmapoopathy, Vennila Ponnusamy, Adina T. Michael-Titus, Philippa Chisholm

Publikováno v: Frontiers in Neurology, Vol 11 (2020)

Aim: To determine the predictive value of plasma neurofilament light protein (NfL) as a prognostic marker for outcomes in babies who have undergone therapeutic hypothermia (TH) for hypoxic ischemic encephalopathy (HIE).Method: NfL levels from three g

Externí odkaz: https://doaj.org/article/fa118f3f1373492c86894a53dc1adcc8

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WITHDRAWN: In clinical practice, cerebral MRI in newborns is highly predictive of neurodevelopmental outcome after therapeutic hypothermia.

Autor: Tharmapoopathy P; The Royal London Hospital, Barts Health NHS Trust, London, E1 1BB, UK; Centre for Neuroscience & Trauma, Blizard Institute, Barts, The London School of Medicine and Dentistry, Queen Mary University of London, London, E1 2AT, UK., Chisholm P; Homerton University Hospitals NHS Foundation Trust, London, E9 6SR, UK., Barlas A; The Royal London Hospital, Barts Health NHS Trust, London, E1 1BB, UK., Varsami M; The Royal London Hospital, Barts Health NHS Trust, London, E1 1BB, UK., Gupta N; University Hospital Southampton, Southampton, UK., Ekitzidou G; Homerton University Hospitals NHS Foundation Trust, London, E9 6SR, UK., Ponnusamy V; Ashford and St. Peter's Hospitals NHS Foundation Trust, Chertsey, UK; Centre for Genomics & Child Health, Blizard Institute, Barts, The London School of Medicine and Dentistry, Queen Mary University of London, London E1 2AT, UK., Kappelou O; Homerton University Hospitals NHS Foundation Trust, London, E9 6SR, UK., Evanson J; The Royal London Hospital, Barts Health NHS Trust, London, E1 1BB, UK., Rosser G; Centre for Genomics & Child Health, Blizard Institute, Barts, The London School of Medicine and Dentistry, Queen Mary University of London, London E1 2AT, UK., Shah DK; The Royal London Hospital, Barts Health NHS Trust, London, E1 1BB, UK; Centre for Neuroscience & Trauma, Blizard Institute, Barts, The London School of Medicine and Dentistry, Queen Mary University of London, London, E1 2AT, UK. Electronic address: d.shah@qmul.ac.uk.

Publikováno v: European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society [Eur J Paediatr Neurol] 2019 Sep 11. Date of Electronic Publication: 2019 Sep 11.

Newborns with Favourable Outcomes after Perinatal Asphyxia Have Upregulated Glucose Metabolism-Related Proteins in Plasma.

Autor: Yip, Ping K.¹ (AUTHOR) p.yip@qmul.ac.uk, Bremang, Michael² (AUTHOR) ian.pike@proteomics.com, Pike, Ian² (AUTHOR), Ponnusamy, Vennila^1,3 (AUTHOR) a.t.michael-titus@qmul.ac.uk, Michael-Titus, Adina T.¹ (AUTHOR) d.shah@qmul.ac.uk, Shah, Divyen K.^1,4 (AUTHOR)

Publikováno v: Biomolecules (2218-273X). Oct2023, Vol. 13 Issue 10, p1471. 25p.