Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Tharmala Tharmalingam"'
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 18, Iss 2 (2022)
Passive immunization with polyclonal hyper immunoglobulin (HIG) therapy represents a proven strategy by transferring immunoglobulins to patients to confer immediate protection against a range of pathogens including infectious agents and toxins. Disti
Externí odkaz:
https://doaj.org/article/7f0c04f41bd642eebfa1071634711175
Publikováno v:
Human vaccinesimmunotherapeutics. 18(2)
Passive immunization with polyclonal hyper immunoglobulin (HIG) therapy represents a proven strategy by transferring immunoglobulins to patients to confer immediate protection against a range of pathogens including infectious agents and toxins. Disti
Autor:
Sean Fair, Stephen D. Carrington, James P Hanrahan, Patrick Lonergan, Tharmala Tharmalingam, Lorraine Richardson, Alexander C.O. Evans
Publikováno v:
Reproduction (Cambridge, England). 157(3)
The aim of this study was to investigate the properties and to functionally characterize the cervical mucus that modulates sperm transport through the cervix by using ewe breeds with a divergent pregnancy rate (Belclare and Suffolk; high and low, res
Autor:
Kristi Daris, Tharmala Tharmalingam, Pheng Yam, Nicole Tejeda, Sam Yaghmour, Fang Lu, Jennitte Stevens, Chetan T. Goudar, Hedieh Barkhordarian, Trent P. Munro
Publikováno v:
Biotechnology Progress
Regulatory guidelines require the sponsors to provide assurance of clonality of the production cell line, and when such evidence is not available, additional studies are typically required to further ensure consistent long-term manufacturing of the p
Publikováno v:
Biotechnology and Bioengineering. 112:1146-1154
Glycosylation is a critical characteristic of biotherapeutics because of its central role in in vivo efficacy. Multiple factors including medium composition and process conditions impact protein glycosylation and characterizing cellular response to t
Publikováno v:
Biotechnology and Bioengineering. 112:832-837
Pluronic® F68 (P-F68) is an important component of chemically-defined cell culture medium because it protects cells from hydrodynamic and bubble-induced shear in the bioreactor. While P-F68 is typically used in cell culture medium at a concentration
Autor:
Alexander C.O. Evans, Pauline M. Rudd, Siobhan W. Walsh, Oscar G. Potter, Stephen Carrington, Paul A. McGettigan, Weston B. Struwe, Tharmala Tharmalingam-Jaikaran
Publikováno v:
REPRODUCTION. 148:569-580
Follicular fluid (FF), an important microenvironment for the development of oocytes, contains many proteins that are glycosylated withN-linked glycans. This study aimed i) to present an initial analysis of theN-linked glycan profile of bovine FF usin
Autor:
H Almhanna, Colm J. Reid, Mary Gallagher, Alexander C.O. Evans, Beatriz Fernandez-Fuertes, Khalid M Alkhodair, Tharmala Tharmalingam, Jim McGetrick, S Gedair, Stephen D. Carrington, E. Fitzpatrick, P B Larsen, Patrick Lonergan
Publikováno v:
Reproduction (Cambridge, England). 155(4)
Sialic acid (Sia) is a major constituent of both the sperm glycocalyx and female reproductive mucosal surface and is involved in regulating sperm migration, uterotubal reservoir formation and oocyte binding. Siglecs (sialic acid-binding immunoglobuli
Autor:
Ákos Szekrényes, Niclas G. Karlsson, András Guttman, Ronan M. Kelly, Barbara Adamczyk, Pauline M. Rudd, Michael Schomberg, Tharmala Tharmalingam-Jaikaran
Publikováno v:
Carbohydrate Research
Carbohydrate Research; Vol 389
Carbohydrate Research; Vol 389
The IgG N-glycome provides sufficient complexity and information content to serve as an excellent source for biomarker discovery in mammalian health. Since oligosaccharides play a significant role in many biological processes it is very important to
Publikováno v:
Glycoconjugate Journal; Vol 30
Many post-translational modifications, including glycosylation, are pivotal for the structural integrity, location and functional activity of glycoproteins. Sub-populations of proteins that are relocated or functionally changed by such modifications