Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Tharine Dal-Cim"'
Autor:
Laíse Figueiredo de Oliveira, Gabriela Godoy Poluceno, Tuane Bazanella Sampaio, Leandra Celso Constantino, Ana Paula Costa, Wagner Carbolin Martins, Tharine Dal-Cim, Karen Andrinéia de Oliveira, Fabiana Kalyne Ludka, Rui Daniel Prediger, Frederico C. Pereira, Carla Inês Tasca
Publikováno v:
Neurotoxicity research.
Neonatal exposure to general anesthetics has been associated with neurotoxicity and morphologic changes in the developing brain. Isoflurane is a volatile anesthetic widely used in pediatric patients to induce general anesthesia, analgesia, and periop
Autor:
Carla I. Tasca, Karen Andrinéia de Oliveira, Cláudia Beatriz Nedel, Gabriela Godoy Poluceno, Tharine Dal-Cim, Débora Lanznaster
Publikováno v:
Purinergic Signalling. 15:465-476
Glial cells are involved in multiple cerebral functions that profoundly influence brain tissue viability during ischemia, and astrocytes are the main source of extracellular purines as adenosine and guanosine. The endogenous guanine-based nucleoside
Autor:
Carina Rodrigues Boeck, Helena Decker, Sheila S. Francisco, Cláudia Beatriz Nedel, Tetsadê C. B. Piermartiri, Tharine Dal-Cim, Vivaldo Moura-Neto, Carla I. Tasca, Luciana Romão
Publikováno v:
Purinergic Signalling. 15:439-450
The guanine-based purines (GBPs) have essential extracellular functions such as modulation of glutamatergic transmission and trophic effects on neurons and astrocytes. We previously showed that GBPs, such as guanosine-5'-monophosphate (GMP) or guanos
Autor:
Tharine Dal-Cim, Wagner C. Martins, Gabriela Godoy Poluceno, Frederico C. Pereira, Fabiana K. Ludka, Rui Daniel Prediger, Ana Paula Costa, Carla I. Tasca, Karen Andrinéia de Oliveira, Tuane Bazanella Sampaio, Laíse Figueiredo de Oliveira, Leandra C. Constantino
Publikováno v:
Neurotoxicity Research. 34:649-659
The neonatal exposure to general anesthetics has been associated with neuronal apoptosis and dendritic spines morphologic changes in the developing brain. Ketamine, a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, is widely used in p
Autor:
Javier Egea, Carla I. Tasca, Maria Dolores Martin-de-Saavedra, Manuela G. López, Simone Molz, Josiane Budni, Tharine Dal-Cim, Ana Lúcia S. Rodrigues
Publikováno v:
Molecular Neurobiology. 55:1580-1589
Folic acid (folate) is a vitamin of the B-complex group crucial for neurological function. Considering that excitotoxicity and cell death induced by glutamate are involved in many disorders, the potential protective effect of folic acid on glutamate-
Autor:
Leandra C. Constantino, Andréa D.E. Zomkowski, Luisa Bandeira Binder, Fabiana K. Ludka, Ana Lúcia S. Rodrigues, Tharine Dal-Cim, Carla I. Tasca
Publikováno v:
Journal of Psychiatric Research. 82:50-57
Atorvastatin is a cholesterol-lowering statin that has been shown to exert several pleiotropic effects in the nervous system as a neuroprotective and antidepressant-like agent. Antidepressant-like effect of atorvastatin in mice is mediated by glutama
Autor:
Tharine, Dal-Cim, Gabriela G, Poluceno, Débora, Lanznaster, Karen A, de Oliveira, Claudia B, Nedel, Carla I, Tasca
Publikováno v:
Purinergic signalling. 15(4)
Glial cells are involved in multiple cerebral functions that profoundly influence brain tissue viability during ischemia, and astrocytes are the main source of extracellular purines as adenosine and guanosine. The endogenous guanine-based nucleoside
Autor:
Tharine Dal-Cim, Carla I. Tasca, Wagner C. Martins, Leandra C. Constantino, Mauricio P. Cunha, Ana Lúcia S. Rodrigues, Fabiana K. Ludka, Caio M. Massari, Luisa Bandeira Binder
Publikováno v:
Molecular Neurobiology. 54:6163-6173
Intracerebroventricular (icv) amyloid-beta (Aβ)1–40 infusion to mice has been demonstrated to cause neurotoxicty and depressive-like behavior and it can be used to evaluate antidepressant and neuroprotective effect of drugs. Atorvastatin is a wide
Autor:
Mauricio P. Cunha, Débora Lanznaster, Tharine Dal-Cim, Wagner C. Martins, Carla I. Tasca, Daniel Tonial Thomaz, Andreza Fabro de Bem
Publikováno v:
Purinergic Signalling. 12:707-718
Guanosine, the endogenous guanine nucleoside, prevents cellular death induced by ischemic events and is a promising neuroprotective agent. During an ischemic event, nitric oxide has been reported to either cause or prevent cell death. Our aim was to
Autor:
Tharine Dal-Cim, Diogo O. Souza, Débora Lanznaster, Gisele Hansel, Josiel Mileno Mack, Rui Daniel Prediger, Marcelo Ganzella, Eduardo R. Zimmer, Roberto Farina de Almeida, Victor Coelho, Carla I. Tasca
Publikováno v:
Molecular Neurobiology. 54:5482-5496
Amyloid-beta (Aβ) peptides are the major neuropathological hallmarks related with Alzheimer's disease (AD). Aβ peptides trigger several biochemical mechanisms of neurotoxicity, including neuroinflammation and glutamatergic neurotransmission impairm