Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Tharin M A, Blumenschein"'
Autor:
Colin J. Macdonald, Andreas Ioannis Karsisiotis, Tharin M. A. Blumenschein, Oliver M. Deacon, Geoffrey R. Moore, Jonathan A. R. Worrall
Publikováno v:
Biomolecular NMR Assignments. 11:165-168
Human cytochrome c plays a central role in the mitochondrial electron transfer chain and in the intrinsic apoptosis pathway. Through the interaction with the phospholipid cardiolipin, cytochrome c triggers release of pro-apoptotic factors, including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::196e28f0f3ba12623b14355941ca3b82
https://doi.org/10.1007/s12104-017-9740-0
https://doi.org/10.1007/s12104-017-9740-0
Autor:
Jessica E. Watt, Tharin M. A. Blumenschein, Lloyd C. Wahl, Danielle De Bourcier, Andrew Chantry, Hiu T. T. Yim, Surinder M. Soond, James Tolchard
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 19, p 4682 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 19
University of East Anglia digital repository
UnpayWall
ORCID
Microsoft Academic Graph
PubMed Central
Datacite
DOAJ-Articles
Multidisciplinary Digital Publishing Institute
International Journal of Molecular Sciences
Volume 20
Issue 19
University of East Anglia digital repository
UnpayWall
ORCID
Microsoft Academic Graph
PubMed Central
Datacite
DOAJ-Articles
Multidisciplinary Digital Publishing Institute
HECT) comprising WW3&ndash
signalling pathway activity, providing a further layer of complexity and feedback to the WWP2 regulatory apparatus. Collectively, our data reveal a structural platform for Smad substrate selection by WWP2 isoform WW do
signalling pathway activity, providing a further layer of complexity and feedback to the WWP2 regulatory apparatus. Collectively, our data reveal a structural platform for Smad substrate selection by WWP2 isoform WW do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d77a11671c3a9bd224a84c0e7c0412e8
https://www.mdpi.com/1422-0067/20/19/4682
https://www.mdpi.com/1422-0067/20/19/4682
Autor:
Danielle De Bourcier, Andrew Chantry, Tharin M. A. Blumenschein, Lloyd C. Wahl, Jessica E. Watt
Publikováno v:
Biophysical Journal. 118:182a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bb19321c70045afa6185a28ee75090a
https://doi.org/10.1016/j.bpj.2019.11.1113
https://doi.org/10.1016/j.bpj.2019.11.1113
Autor:
James Tolchard, Samuel J. Walpole, Andrew J. Miles, Robin Maytum, Lawrence A. Eaglen, Ted Hackstadt, B. A. Wallace, Tharin M. A. Blumenschein
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Tarp (translocated actin recruiting phosphoprotein) is an effector protein common to all chlamydial species that functions to remodel the host-actin cytoskeleton during the initial stage of infection. In C. trachomatis, direct binding to actin monome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4c94687c2f4a510055737126c2593605
https://ueaeprints.uea.ac.uk/id/eprint/65987/
https://ueaeprints.uea.ac.uk/id/eprint/65987/
Autor:
Badri S. Rajagopal, Colin J. Macdonald, Jonathan A. R. Worrall, Geoffrey R. Moore, Tharin M. A. Blumenschein, Oliver M. Deacon, Andreas Ioannis Karsisiotis
Publikováno v:
Biomolecular NMR Assignments. 9:415-419
Human cytochrome c is a multi-functional protein with key roles in both the mitochondrial electron transfer chain and in apoptosis. In the latter, a complex formed between the mitochondrial phospholipid cardiolipin and cytochrome c is crucial for ins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6936c560a946a075c396844e5d2ce81
https://doi.org/10.1007/s12104-015-9621-3
https://doi.org/10.1007/s12104-015-9621-3
Autor:
James, Tolchard, Samuel J, Walpole, Andrew J, Miles, Robin, Maytum, Lawrence A, Eaglen, Ted, Hackstadt, B A, Wallace, Tharin M A, Blumenschein
Publikováno v:
Scientific Reports
Tarp (translocated actin recruiting phosphoprotein) is an effector protein common to all chlamydial species that functions to remodel the host-actin cytoskeleton during the initial stage of infection. In C. trachomatis, direct binding to actin monome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::538febc9047adabb2d097c5ae25a6e9e
https://pubmed.ncbi.nlm.nih.gov/29386631
https://pubmed.ncbi.nlm.nih.gov/29386631
Autor:
T. Moreno-Chicano, Oliver M. Deacon, Colin J. Macdonald, Andreas Ioannis Karsisiotis, Jonathan A. R. Worrall, Michael T. Wilson, Tharin M. A. Blumenschein, Geoffrey R. Moore, Michael A. Hough
Publikováno v:
Biochemistry. 56(46)
Proteins performing multiple biochemical functions are called “moonlighting proteins” or extreme multifunctional (EMF) proteins. Mitochondrial cytochrome c is an EMF protein that binds multiple partner proteins to act as a signaling molecule, tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92c8b251af4a74913d1a8f15170ad36b
https://pubmed.ncbi.nlm.nih.gov/29083920
https://pubmed.ncbi.nlm.nih.gov/29083920
Autor:
Michael T. Wilson, Andreas Ioannis Karsisiotis, Colin J. Macdonald, Tharin M. A. Blumenschein, Geoffrey R. Moore, Oliver M. Deacon, Jonathan A. R. Worrall
Publikováno v:
Scientific Reports
Thrombocytopenia 4 is an inherited autosomal dominant thrombocytopenia, which occurs due to mutations in the human gene for cytochrome c that results in enhanced mitochondrial apoptotic activity. The Gly41Ser mutation was the first to be reported. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1ac0cdbb04f1d9f6aee05692eb7272a
https://pubmed.ncbi.nlm.nih.gov/27461282
https://pubmed.ncbi.nlm.nih.gov/27461282
Autor:
Andreas Ioannis Karsisiotis, Jonathan A. R. Worrall, Colin J. Macdonald, Oliver M. Deacon, Michael T. Wilson, Tharin M. A. Blumenschein, Geoffrey R. Moore
Publikováno v:
Biophysical Journal. 112:32a-33a
In addition to its well-known role as a component of the electron transport chain, mitochondrial cytochrome c can also act as a peroxidase in the early stages of the intrinsic apoptosis pathway. Ferricytochrome c contains a hexacoordinated heme iron,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f73a24431cb4d9a2c86c587db8fcba0d
https://doi.org/10.1016/j.bpj.2016.11.210
https://doi.org/10.1016/j.bpj.2016.11.210
Autor:
Joe Win, Stuart R. F. King, Richard K. Hughes, Thomas A. Clarke, Sophien Kamoun, Mark J. Banfield, Tharin M. A. Blumenschein, Laurence S. Boutemy
Publikováno v:
Journal of Biological Chemistry. 286:35834-35842
Phytopathogens deliver effector proteins inside host plant cells to promote infection. These proteins can also be sensed by the plant immune system, leading to restriction of pathogen growth. Effector genes can display signatures of positive selectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4bcd25430544aa6497b957374fb5d7ab
https://doi.org/10.1074/jbc.m111.262303
https://doi.org/10.1074/jbc.m111.262303