Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Tharappel C. James"'
Autor:
Tharappel C James, Ursula Bond
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49728 (2012)
A key requirement for the development of cancer immunotherapy is the identification of tumour-associated antigens that are differentially or exclusively expressed on the tumour and recognized by the host immune system. However, immune responses to su
Externí odkaz:
https://doaj.org/article/03919a36746f406188412e38167ce57c
Autor:
Chandre Monerawela, Nikolaos Vakirlis, Gavin J. McManus, Aoife McLysaght, Tharappel C. James, Orquidea Ribeiro, Ursula Bond
Publikováno v:
Yeast
The sequencing of over a thousand Saccharomyces cerevisiae genomes revealed a complex pangenome. Over one third of the discovered genes are not present in the S. cerevisiae core genome but instead are often restricted to a subset of yeast isolates an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb953c886e9b4a6a68ba1081b055ad70
https://pubmed.ncbi.nlm.nih.gov/30963617
https://pubmed.ncbi.nlm.nih.gov/30963617
Publikováno v:
Applied and Environmental Microbiology. 82:4288-4298
Antimicrobial peptides offer potential as novel therapeutics to combat food spoilage and poisoning caused by pathogenic and nonpathogenic bacteria. Our previous studies identified the peptide human beta-defensin 3 (HBD3) as a potent antimicrobial age
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bd2dc0825ae468777349a41733bfe46
https://doi.org/10.1128/aem.00558-16
https://doi.org/10.1128/aem.00558-16
Autor:
Ursula Bond, P. Bourke, Jean Titze, J. Kavanagh, Lorna Gallagher, Tharappel C. James, Elke K. Arendt
Publikováno v:
Journal of Applied Microbiology. 116:368-379
Aims To examine the use of a natural antimicrobial peptide, human β-defensin-3 (HBD3), as a means of preventing spoilage from bacterial contamination in brewery fermentations and in bottled beer. Methods and Results A chemically synthesised HBD3 pep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32874b0415e7e8b548de899856aa47ba
https://doi.org/10.1111/jam.12382
https://doi.org/10.1111/jam.12382
Publikováno v:
Current Genetics. 53:139-152
A long-term goal of the brewing industry is to identify yeast strains with increased tolerance to the stresses experienced during the brewing process. We have characterised the genomes of a number of stress-tolerant mutants, derived from the lager ye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a2616f18ddbe09b483a3905f1c0be26
https://doi.org/10.1007/s00294-007-0172-8
https://doi.org/10.1007/s00294-007-0172-8
Publikováno v:
FEMS yeast research. 15(2)
Lager yeasts, Saccharomyces pastorianus , are interspecies hybrids between S. cerevisiae and S. eubayanus and are classified into Group I and Group II clades. The genome of the Group II strain, Weihenstephan 34/70, contains eight so-called ‘lager-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49d16984879dd10b51f96ae81552e36a
https://pubmed.ncbi.nlm.nih.gov/25673756
https://pubmed.ncbi.nlm.nih.gov/25673756
Autor:
Jessica McMahon, Tharappel C. James, Susan Gaines, Grace Mulcahy, Andrew T. Lloyd, David J. Lynn, Cliona O'Farrelly, Rowan Higgs, Joanna Tierney
Publikováno v:
Immunogenetics. 57:90-98
Antimicrobial peptides are essential components of innate immunity and are generally thought to act by disrupting the membrane integrity of microbes. Here we report the discovery of two novel chicken beta-defensins, gallinacin (Gal)-11 and Gal-12, fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7917fd773d5537125375931af7e6020e
https://doi.org/10.1007/s00251-005-0777-3
https://doi.org/10.1007/s00251-005-0777-3
Publikováno v:
Current Genetics. 45:360-370
Competitive comparative genome hybridisation (CCGH) to Saccharomyces cerevisiae DNA microarrays and quantitative real-time polymerase chain reaction (qRT-PCR) assays are used to examine the copy number of S. cerevisiae-like genes, at single gene reso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d65c0ec6b4c3132901901059206f07fc
https://doi.org/10.1007/s00294-004-0504-x
https://doi.org/10.1007/s00294-004-0504-x
Publikováno v:
Journal of Microbiological Methods. 54:315-323
Adherence to the tooth surface by Streptococcus mutans is an important step in initiation of dental caries. Current in vitro methods used to study bacterial adherence are time-consuming and may involve the use of radiolabels. The aim of this study wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc80adc24f504377bc49ea818119f5d0
https://doi.org/10.1016/s0167-7012(03)00015-0
https://doi.org/10.1016/s0167-7012(03)00015-0
Publikováno v:
Proceedings of the IEEE. 90:1887-1899
With the advent of whole genome sequencing, it is now possible to get a complete picture of the cellular activities of an organism. One important tool in the era of functional genomics is the examination of the transcript expression patterns of the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a66210c4c5a68516dcf3a25f8611c729
https://doi.org/10.1109/jproc.2002.805300
https://doi.org/10.1109/jproc.2002.805300