Zobrazeno 1 - 2
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pro vyhledávání: '"Tharanga M R Ramanayake Mudiyanselage"'
Autor:
Masataka Michigami, Tharanga M. R. Ramanayake Mudiyanselage, Miho Suzuki, Hirotsugu Ishizako, Kunpei Notsu, Kikuya Sugiura, Ikuo Fujii
Publikováno v:
ACS Chemical Biology. 17:647-653
As a small affinity molecule to serve as an alternative to antibodies, we have developed a conformationally constrained peptide with a de novo designed helix-loop-helix (HLH) scaffold. To evaluate its potential for biomedical applications, we perform
Autor:
Masataka Michigami, Atsuko Uyeda, Ikuo Fujii, Tharanga M R Ramanayake Mudiyanselage, Zhengmao Ye, Kikuya Sugiura, Norimitsu Inoue, Daisuke Fujiwara
Publikováno v:
ACS Chemical Biology. 15:360-368
Molecular-targeting peptides and mini-proteins are promising alternatives to antibodies in a wide range of applications in bioscience and medicine. We have developed a helix-loop-helix (HLH) peptide as an alternative to antibodies to inhibit specific