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Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
αD-conotoxins are 11 kDa homodimers that potently inhibit nicotinic acetylcholine receptors (nAChRs) through a non-competitive (allosteric) mechanism. In this study, we describe the allosteric binding mode of the granulin-like C-terminal (CTD) of Vx
Externí odkaz:
https://doaj.org/article/1bbe3088b29c42e59b5e011995cb27b8