Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Thao M. Nguyen"'
Autor:
Thao M. Nguyen, Paul Joyce, David M. Ross, Kristen Bremmell, Manasi Jambhrunkar, Sook S. Wong, Clive A. Prestidge
Publikováno v:
Pharmaceutics, Vol 16, Iss 2, p 209 (2024)
MP-A08 is a novel sphingosine kinase 1 (SPHK1) inhibitor with activity against acute myeloid leukemia (AML). A rationally designed liposome-based encapsulation and delivery system has been shown to overcome the physicochemical challenges of MP-A08 an
Externí odkaz:
https://doaj.org/article/755cd84cdc034bce8bff0cbcf3abbb9e
Autor:
Alexander C. Lewis, Victoria S. Pope, Melinda N. Tea, Manjun Li, Gus O. Nwosu, Thao M. Nguyen, Craig T. Wallington-Beddoe, Paul A. B. Moretti, Dovile Anderson, Darren J. Creek, Maurizio Costabile, Saira R. Ali, Chloe A. L. Thompson-Peach, B. Kate Dredge, Andrew G. Bert, Gregory J. Goodall, Paul G. Ekert, Anna L. Brown, Richard D’Andrea, Nirmal Robinson, Melissa R. Pitman, Daniel Thomas, David M. Ross, Briony L. Gliddon, Jason A. Powell, Stuart M. Pitson
Inducing cell death by the sphingolipid ceramide is a potential anticancer strategy, but the underlying mechanisms remain poorly defined. In this study, triggering an accumulation of ceramide in acute myeloid leukemia (AML) cells by inhibition of sph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ed8fbe2daf653ebbee791ab6b83276b
https://hdl.handle.net/11541.2/31406
https://hdl.handle.net/11541.2/31406
Autor:
Deborah, Toledo-Flores, Anna, Williamson, Nisha, Schwarz, Sanuja, Fernando, Catherine, Dimasi, Tyra A, Witt, Thao M, Nguyen, Amrutesh S, Puranik, Colin D, Chue, Sinny, Delacroix, Daniel B, Spoon, Claudine S, Bonder, Christina A, Bursill, Belinda A, Di Bartolo, Stephen J, Nicholls, Robert D, Simari, Peter J, Psaltis
Publikováno v:
Scientific Reports
The cellular origins of vasa vasorum are ill-defined and may involve circulating or local progenitor cells. We previously discovered that murine aortic adventitia contains Sca-1+CD45+ progenitors that produce macrophages. Here we investigated whether
Publikováno v:
Chromatography, Vol 2, Iss 3, Pp 422-435 (2015)
Gold nanorods (GNRs) are of particular interest for biomedical applications due to their unique size-dependent longitudinal surface plasmon resonance band in the visible to near-infrared. Purified GNRs are essential for the advancement of technologie
Publikováno v:
Nanomedicine. 9:2263-2272
Aim: To uptake and release hydrophilic model drugs and insulin in a novel conductive polymer (CP) nanotube transdermal patch. Materials & methods: The externally controlled transdermal delivery of model drugs and insulin were tested ex vivo and resul
Publikováno v:
Analytical and Bioanalytical Chemistry. 406:1651-1659
The development of highly efficient asymmetric-flow field flow fractionation (A4F) methodology for biocompatible PEGylated gold nanorods (GNR) without the need for surfactants in the mobile phase is presented. We report on the potential of A4F for ra
Publikováno v:
Nanomedicine. 6:921-928
Treatment for intoxication involves the neutralization or clearance of a toxic compound, but the current methods of treatment are limited in their ability to safely and effectively detoxify the patient. Emerging research has focused on using nanopart
Publikováno v:
Macromolecules. 44:1385-1392
The geometry of a catalyst support has a strong influence on the catalytic activity of heterogeneous metallocene catalysts for polymerization of α-olefins and styrene. In this study, the catalytic activities of Cp*Ti(OCH3)3/MAO catalyst for styrene
Publikováno v:
Analytical and bioanalytical chemistry. 408(9)
The control of gold nanorod (GNR) solution-based syntheses has been hindered in part by the inability to examine and control the conversion of precursor seed populations to anisotropic materials, which have resulted in low yields of desired products
Autor:
Julien Gigault, Thao M. Nguyen, John M. Pettibone, Robert I. MacCuspie, Tae Joon Cho, Vincent A. Hackley, Justin M. Gorham
Publikováno v:
Langmuir : the ACS journal of surfaces and colloids. 31(27)
Cationic polyethylenimine conjugated gold nanoparticles (AuNP-PEI) are a widely studied vector for drug delivery and an effective probe for interrogating NP-cell interactions. However, an inconsistent body of literature currently exists regarding the