Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Thanthrige Thiunuwan Priyathilaka"'
Autor:
Aditya Rayasam, Julie A. Kijak, Lee Kissel, Yun Hwa Choi, Taehee Kim, Martin Hsu, Dinesh Joshi, Collin J. Laaker, Peter Cismaru, Anders Lindstedt, Krisztian Kovacs, Raghu Vemuganti, Shing Yan Chiu, Thanthrige Thiunuwan Priyathilaka, Matyas Sandor, Zsuzsanna Fabry
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-15 (2022)
Abstract Background Ischemic stroke is a leading cause of mortality worldwide, largely due to the inflammatory response to brain ischemia during post-stroke reperfusion. Despite ongoing intensive research, there have not been any clinically approved
Externí odkaz:
https://doaj.org/article/e710bc3210a84704b042530e01331994
Autor:
Thanthrige Thiunuwan Priyathilaka, Collin James Laaker, Melinda Herbath, Zsuzsanna Fabry, Matyas Sandor
Publikováno v:
Translational Research. 250:18-35
Bacteria, fungi, viruses, and protozoa are known to infect and induce diseases in the human central nervous system (CNS). Modeling the mechanisms of interaction between pathogens and the CNS microenvironment is essential to understand their pathophys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3372b52525eb6f4320688db524330b2
https://doi.org/10.1016/j.trsl.2022.06.013
https://doi.org/10.1016/j.trsl.2022.06.013
Autor:
M.D. Neranjan Tharuka, K.A.S.N. Shanaka, Hyerim Yang, Jehee Lee, Thanthrige Thiunuwan Priyathilaka, Sarithaa Sellaththurai
Publikováno v:
Fish & Shellfish Immunology. 99:59-72
Innate immunity is characterized by nonspecific, prompt reactions toward armada of antigens. Animals funnel down a repertoire of immune stimulants to activate non-selective defense mechanisms rapidly. This study was conducted to characterize the rock
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f3725553787c00f9ca050e52d62242f
https://doi.org/10.1016/j.fsi.2020.01.060
https://doi.org/10.1016/j.fsi.2020.01.060
Autor:
Dinesh C. Joshi, Krisztian Kovacs, Collin Laaker, Thanthrige Thiunuwan Priyathilaka, Shing Yan Chiu, TaeHee Kim, Peter Cismaru, Julie A. Kijak, Lee Kissel, Raghu Vemuganti, Matyas Sandor, Martin Hsu, Anders Lindstedt, Zsuzsanna Fabry, Aditya Rayasam
Background: Ischemic stroke is a leading cause of mortality worldwide, largely due to the inflammatory response to brain ischemia during post-stroke reperfusion. Despite ongoing intensive research, there have not been any clinically approved drugs ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::709cb24ba18707a6d07bb2b2b47ab201
https://doi.org/10.21203/rs.3.rs-1032310/v1
https://doi.org/10.21203/rs.3.rs-1032310/v1
Autor:
Sumi Jung, Thanthrige Thiunuwan Priyathilaka, Myoung-Jin Kim, N.D. Janson, Nilojan Jehanathan, Jehee Lee, Bo-Hye Nam
Publikováno v:
Fish & Shellfish Immunology. 93:597-611
The transcription factor, activator protein-1 (AP-1), is a dimeric protein and a downstream member of the mitogen-activated protein kinase (MAPK) signaling pathway. It regulates a wide array of functions including, cell proliferation, survival, diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98772ca44964a67f083b5fa1481d06b4
https://doi.org/10.1016/j.fsi.2019.08.013
https://doi.org/10.1016/j.fsi.2019.08.013
Publikováno v:
Fish & Shellfish Immunology. 92:655-666
Viperin, also known as RSAD2 (Radical S-adenosyl methionine domain containing 2), is an interferon-induced endoplasmic reticulum-associated antiviral protein. Previous studies have shown that viperin levels are elevated in the presence of viral RNA,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c734d62f2419abf1d965682a908b6c6
https://doi.org/10.1016/j.fsi.2019.06.015
https://doi.org/10.1016/j.fsi.2019.06.015
Autor:
Thanthrige Thiunuwan Priyathilaka, Hyerim Yang, Jehee Lee, Seongdo Lee, W.M. Gayashani Sandamalika
Publikováno v:
Fish & Shellfish Immunology. 91:159-171
Representing a multifunctional complex group of proteins, glutathione S- transferases (GSTs) play a major role in the phase II detoxification process in a wide range of organisms. This study focused on the potential detoxification ability of disk aba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a29b6bd14acc6fd087a0fe05e5ca6a9
https://doi.org/10.1016/j.fsi.2019.04.004
https://doi.org/10.1016/j.fsi.2019.04.004
Publikováno v:
Fish & Shellfish Immunology. 87:32-42
Phospholipid scramblases (PLSCRs) are a family of transmembrane proteins known to be responsible for Ca2+-mediated bidirectional phospholipid translocation in the plasma membrane. Apart from the scrambling activity of PLSCRs, recent studies revealed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3827aa90c65642ee018ab9fa9993d71
https://doi.org/10.1016/j.fsi.2018.12.044
https://doi.org/10.1016/j.fsi.2018.12.044
Autor:
M.D. Neranjan Tharuka, Jehee Lee, Chaehyeon Lim, Thanthrige Thiunuwan Priyathilaka, Jeongeun Kim
Publikováno v:
Fish & Shellfish Immunology. 86:230-238
Arachidonate 5-lipoxygenase (ALOX5) is an essential enzyme for the biosynthesis of leukotrienes, which are pro-inflammatory and anti-inflammatory mediators. In this study, the ALOX5 paralog of the big-belly seahorse (Hippocampus abdominalis; HaALOX5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1871480a57a9a3b460bfd7ee78774c99
https://doi.org/10.1016/j.fsi.2018.11.042
https://doi.org/10.1016/j.fsi.2018.11.042
Autor:
Seongdo Lee, Hyukjae Kwon, Jehee Lee, W.K.M. Omeka, Thanthrige Thiunuwan Priyathilaka, D.S. Liyanage
Publikováno v:
Fish & Shellfish Immunology. 84:158-168
The structural and evolutionary linkage between tumor necrosis factor (TNF) and the globular C1q (gC1q) domain defines the C1q and TNF-related proteins (CTRPs), which are involved in diverse functions such as immune defense, inflammation, apoptosis,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b299a5c7aafca94978e77ff181dff6f2
https://doi.org/10.1016/j.fsi.2018.09.078
https://doi.org/10.1016/j.fsi.2018.09.078