Výsledky vyhledávání - "Thansita Bhunyakarnjanarat"

Akademický článek

Obesity Exacerbates Lupus Activity in Fc Gamma Receptor IIb Deficient Lupus Mice Partly through Saturated Fatty Acid-Induced Gut Barrier Defect and Systemic Inflammation

Autor: Kanyarat Udompornpitak, Awirut Charoensappakit, Kritsanawan Sae-Khow, Thansita Bhunyakarnjanarat, Cong Phi Dang, Wilasinee Saisorn, Peerapat Visitchanakun, Pornpimol Phuengmaung, Tanapat Palaga, Patcharee Ritprajak, Somkanya Tungsanga, Asada Leelahavanichkul

Publikováno v: Journal of Innate Immunity, Pp 1-22 (2022)

The prevalence of obesity is increasing, and the coexistence of obesity and systemic lupus erythematosus (lupus) is possible. A high-fat diet (HFD) was orally administered for 6 months in female 8-week-old Fc gamma receptor IIb deficient (FcgRIIb−/

Externí odkaz: https://doaj.org/article/7cee6f35c48841f19cce409fdadd8ab9

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Akademický článek

Comparison of the Single Cell Immune Landscape between Subjects with High Mycobacterium tuberculosis Bacillary Loads during Active Pulmonary Tuberculosis and Household Members with Latent Tuberculosis Infection

Autor: Supitcha Kamolratanakul, Wassawon Ariyanon, Kanyarat Udompornpitak, Thansita Bhunyakarnjanarat, Asada Leelahavanichkul, Jittima Dhitavat, Polrat Wilairatana, Wiwat Chancharoenthana

Publikováno v: Cells, Vol 13, Iss 4, p 362 (2024)

It is unclear how the immune system controls the transition from latent tuberculosis (TB) infection (LTBI) to active pulmonary infection (PTB). Here, we applied mass spectrometry cytometry time-of-flight (CyTOF) analysis of peripheral blood mononucle

Externí odkaz: https://doaj.org/article/895f1c21041a41a7864eca8c97268150

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Akademický článek

Polymeric Particle BAM15 Targeting Macrophages Attenuates the Severity of LPS-Induced Sepsis: A Proof of Concept for Specific Immune Cell-Targeted Therapy

Autor: Kanyarat Udompornpitak, Thansita Bhunyakarnjanarat, Wilasinee Saisorn, Chonnavee Manipuntee, Kittawat Plengplang, Samarch Sittichaitaweekul, Panisa Jenphatanapong, Suwasin Udomkarnjananun, Warerat Kaewduangduen, Kasirapat Ariya-anandech, Amanee Samaeng, Numpon Insin, Patcharee Ritprajak, Asada Leelahavanichkul

Publikováno v: Pharmaceutics, Vol 15, Iss 12, p 2695 (2023)

Macrophage polarization requires different energy sources and metabolic processes. Therefore, cell energy interference to alter macrophage functions has been proposed as a treatment for severe inflammatory diseases, including sepsis. In this study, t

Externí odkaz: https://doaj.org/article/5db89dab09c54659aa33a1729848f1d5

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Akademický článek

BAM15, a Mitochondrial Uncoupling Agent, Attenuates Inflammation in the LPS Injection Mouse Model: An Adjunctive Anti-Inflammation on Macrophages and Hepatocytes

Autor: Cong Phi Dang, Jiraphorn Issara-Amphorn, Awirut Charoensappakit, Kanyarat Udompornpitak, Thansita Bhunyakarnjanarat, Wilasinee Saisorn, Kritsanawan Sae-Khow, Asada Leelahavanichkul

Publikováno v: Journal of Innate Immunity, Pp 1-17 (2021)

Controlof immune responses through the immunometabolism interference is interesting for sepsis treatment. Then, expression of immunometabolism-associated genes and BAM15, a mitochondrial uncoupling agent, was explored in a proinflammatory model using

Externí odkaz: https://doaj.org/article/079e87163391467fb833df3fd05cd430

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Akademický článek

Acute Kidney Injury Induced Lupus Exacerbation Through the Enhanced Neutrophil Extracellular Traps (and Apoptosis) in Fcgr2b Deficient Lupus Mice With Renal Ischemia Reperfusion Injury

Autor: Wilasinee Saisorn, Supichcha Saithong, Pornpimol Phuengmaung, Kanyarat Udompornpitak, Thansita Bhunyakarnjanarat, Peerapat Visitchanakun, Awirut Chareonsappakit, Prapaporn Pisitkun, Direkrit Chiewchengchol, Asada Leelahavanichkul

Publikováno v: Frontiers in Immunology, Vol 12 (2021)

Renal ischemia is the most common cause of acute kidney injury (AKI) that might be exacerbate lupus activity through neutrophil extracellular traps (NETs) and apoptosis. Here, the renal ischemia reperfusion injury (I/R) was performed in Fc gamma rece

Externí odkaz: https://doaj.org/article/b07895d2029944a4960bf898795b2883

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Akademický článek

Neutrophil Extracellular Traps in Severe SARS-CoV-2 Infection: A Possible Impact of LPS and (1→3)-β-D-glucan in Blood from Gut Translocation

Autor: Supichcha Saithong, Navaporn Worasilchai, Wilasinee Saisorn, Kanyarat Udompornpitak, Thansita Bhunyakarnjanarat, Ariya Chindamporn, Punyot Tovichayathamrong, Pattama Torvorapanit, Direkrit Chiewchengchol, Wiwat Chancharoenthana, Asada Leelahavanichkul

Publikováno v: Cells, Vol 11, Iss 7, p 1103 (2022)

Due to limited data on the link between gut barrier defects (leaky gut) and neutrophil extracellular traps (NETs) in coronavirus disease 2019 (COVID-19), blood samples of COVID-19 cases—mild (upper respiratory tract symptoms without pneumonia; n =

Externí odkaz: https://doaj.org/article/102363b54d8b449cbdcc1b2c5964a2dd

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Uremia-Induced Gut Barrier Defect in 5/6 Nephrectomized Mice Is Worsened by Candida Administration through a Synergy of Uremic Toxin, Lipopolysaccharide, and (1➔3)-β-D-Glucan, but Is Attenuated by Lacticaseibacillus rhamnosus L34

Autor: Leelahavanichkul, Somkanya Tungsanga, Wimonrat Panpetch, Thansita Bhunyakarnjanarat, Kanyarat Udompornpitak, Pisut Katavetin, Wiwat Chancharoenthana, Piraya Chatthanathon, Naraporn Somboonna, Kriang Tungsanga, Somying Tumwasorn, Asada

Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 5; Pages: 2511

A chronic kidney disease (CKD) causes uremic toxin accumulation and gut dysbiosis, which further induces gut leakage and worsening CKD. Lipopolysaccharide (LPS) of Gram-negative bacteria and (1➔3)-β-D-glucan (BG) of fungi are the two most abundant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=multidiscipl::7d1b249599af691bf32e4e10f92a6d42

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Prominent Indomethacin-Induced Enteropathy in Fcgriib Defi-cient lupus Mice: An Impact of Macrophage Responses and Immune Deposition in Gut

Autor: Peerapat Visitchanakun, Bhumdhanin Chantraprapawat, Wilasinee Saisorn, Asada Leelahavanichkul, Cong Phi Dang, Jiraphorn Issara-Amphorn, Thansita Bhunyakarnjanarat, Kanyarat Udompornpitak

Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 3
International Journal of Molecular Sciences, Vol 22, Iss 1377, p 1377 (2021)

A high dose of NSAIDs, a common analgesic, might induce lupus activity through several NSAIDs adverse effects including gastrointestinal permeability defect (gut leakage) and endotoxemia. Indomethacin (25 mg/day) was orally administered for 7 days in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6af9823d12a79007975b01445b1163c

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Prominent Indomethacin-Induced Enteropathy in Fcgriib

Autor: Thansita, Bhunyakarnjanarat, Kanyarat, Udompornpitak, Wilasinee, Saisorn, Bhumdhanin, Chantraprapawat, Peerapat, Visitchanakun, Cong Phi, Dang, Jiraphorn, Issara-Amphorn, Asada, Leelahavanichkul

Publikováno v: International Journal of Molecular Sciences

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::88a3900f255fb66f1843bac3ae0c0a65
https://pubmed.ncbi.nlm.nih.gov/33573095

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