Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Thanh Thanh L. Nguyen"'
Autor:
Thanh Thanh L. Nguyen, Duan Liu, Huanyao Gao, Zhenqing Ye, Jeong‐Heon Lee, Lixuan Wei, Jia Yu, Lingxin Zhang, Liewei Wang, Tamas Ordog, Richard M. Weinshilboum
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 11, Pp 2758-2771 (2022)
Abstract Alternative polyadenylation (APA) is a common genetic regulatory mechanism that generates distinct 3′ ends for RNA transcripts. Changes in APA have been associated with multiple biological processes and disease phenotypes. However, the rol
Externí odkaz:
https://doaj.org/article/9e5c3f5bc7ca48ffa83f71f51b41317a
Autor:
Rajas P. Kale, Thanh Thanh L. Nguyen, J. Blair Price, Nathanael J. Yates, Ken Walder, Michael Berk, Roy V. Sillitoe, Abbas Z. Kouzani, Susannah J. Tye
Publikováno v:
Frontiers in Human Neuroscience, Vol 15 (2021)
The antidepressant actions of deep brain stimulation (DBS) are associated with progressive neuroadaptations within the mood network, modulated in part, by neurotrophic mechanisms. We investigated the antidepressant-like effects of chronic nucleus acc
Externí odkaz:
https://doaj.org/article/e38ba7c1b5d648cc87329b03f35a04fd
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
Selective serotonin reuptake inhibitors (SSRIs) are a standard of care for the pharmacotherapy of patients suffering from Major Depressive Disorder (MDD). However, only one-half to two-thirds of MDD patients respond to SSRI therapy. Recently, a “mu
Externí odkaz:
https://doaj.org/article/e5d689449b264e1b9f80ff7944baff41
Autor:
Huanyao Gao, Lixuan Wei, Shreya Indulkar, Thanh Thanh. L. Nguyen, Duan Liu, Ming-Fen Ho, Cheng Zhang, Hu Li, Richard M. Weinshilboum, James N. Ingle, Liewei Wang
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-14 (2024)
Abstract Background Endocrine therapy is the most important treatment modality of breast cancer patients whose tumors express the estrogen receptor α (ERα). The androgen receptor (AR) is also expressed in the vast majority (80–90%) of ERα-positi
Externí odkaz:
https://doaj.org/article/0906792d3b1b42248df6ef4f3c484ff2
Autor:
Lixuan Wei, Huanyao Gao, Jia Yu, Huan Zhang, Thanh Thanh L. Nguyen, Yayun Gu, Marie R. Passow, Jodi M. Carter, Bo Qin, Judy C. Boughey, Matthew P. Goetz, Richard M. Weinshilboum, James N. Ingle, Liewei Wang
Publikováno v:
Cancer Research. 83:456-470
Androgen receptor (AR) is expressed in 80% to 90% of estrogen receptor α–positive (ER+) breast cancers. Accumulated evidence has shown that AR is a tumor suppressor and that its expression is associated with improved prognosis in ER+ breast cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edd2c8a92493659d38588ce10d27676d
https://doi.org/10.1158/0008-5472.can-22-1016
https://doi.org/10.1158/0008-5472.can-22-1016
Autor:
Thanh Thanh L Nguyen, Huanyao Gao, Duan Liu, Trudy Janice Philips, Zhenqing Ye, Jeong-Heon Lee, Geng-xian Shi, Kaleigh Copenhaver, Lingxin Zhang, Lixuan Wei, Jia Yu, Huan Zhang, Abhijeet Barath, Maggie Luong, Cheng Zhang, Alexandre Gaspar-Maia, Hu Li, Liewei Wang, Tamas Ordog, Richard M Weinshilboum
Publikováno v:
Nucleic Acids Research. 50:11635-11653
Understanding the function of non-coding genomic sequence variants represents a challenge for biomedicine. Many diseases are products of gene-by-environment interactions with complex mechanisms. This study addresses these themes by mechanistic charac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f36b9a1f6fca746166998b229324880f
https://doi.org/10.1093/nar/gkac1045
https://doi.org/10.1093/nar/gkac1045
Autor:
Liewei Wang, James N. Ingle, Richard M. Weinshilboum, Matthew P. Goetz, Judy C. Boughey, Bo Qin, Jodi M. Carter, Marie R. Passow, Yayun Gu, Thanh Thanh L. Nguyen, Huan Zhang, Jia Yu, Huanyao Gao, Lixuan Wei
Androgen receptor (AR) is expressed in 80% to 90% of estrogen receptor α–positive (ER+) breast cancers. Accumulated evidence has shown that AR is a tumor suppressor and that its expression is associated with improved prognosis in ER+ breast cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cb1104245626daa1bec4cd2439d70fd
https://doi.org/10.1158/0008-5472.c.6514329.v1
https://doi.org/10.1158/0008-5472.c.6514329.v1
Autor:
Liewei Wang, James N. Ingle, Richard M. Weinshilboum, Matthew P. Goetz, Judy C. Boughey, Bo Qin, Jodi M. Carter, Marie R. Passow, Yayun Gu, Thanh Thanh L. Nguyen, Huan Zhang, Jia Yu, Huanyao Gao, Lixuan Wei
Figure S1-9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a4309eff4f38863282fea7b03820f49
https://doi.org/10.1158/0008-5472.22433262.v1
https://doi.org/10.1158/0008-5472.22433262.v1
Autor:
Huanyao Gao, Brandon J. Coombes, Duan Liu, Richard M. Weinshilboum, Daniel C. Kim, Zhenqing Ye, Tamas Ordog, Mark A. Frye, Jeong Heon Lee, Thanh Thanh L. Nguyen, Brenna Sharp, Huaizhi Huang, Liewei Wang, Joanna M. Biernacka
Publikováno v:
Molecular Psychiatry. 26:7454-7464
Bipolar disorder (BD) and obesity are highly comorbid. We previously performed a genome-wide association study (GWAS) for BD risk accounting for the effect of body mass index (BMI), which identified a genome-wide significant single-nucleotide polymor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4ddd61d1c975027ec76dea2023a2267
https://doi.org/10.1038/s41380-021-01274-z
https://doi.org/10.1038/s41380-021-01274-z
Autor:
Richard M. Weinshilboum, Thanh Thanh L. Nguyen, W. Edward Craighead, Rima Kaddurah-Daouk, Duan Liu, Mark A. Frye, Liewei Wang, Yani Wang, Yongxian Zhuang, Drew Neavin, Lingxin Zhang, Helen S. Mayberg, Sisi Qin, Huanyao Gao, Elisabeth B. Binder, Daniel C. Kim, Boadie W. Dunlop, Jia Yu, Erica Liu, Joanna M. Biernacka, Tania Carrillo-Roa
Publikováno v:
Molecular Psychiatry
Selective serotonin reuptake inhibitors (SSRIs) are standard of care for major depressive disorder (MDD) pharmacotherapy, but only approximately half of these patients remit on SSRI therapy. Our previous genome-wide association study identified a sin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96c8d84ba8683d053231ed08625bb888
https://doi.org/10.1038/s41380-020-00940-y
https://doi.org/10.1038/s41380-020-00940-y