Isolation from cattle of a prion strain distinct from that causing bovine spongiform encephalopathy.

Autor: Vincent Béringue, Anna Bencsik, Annick Le Dur, Fabienne Reine, Thanh Lan Laï, Nathalie Chenais, Gaëlle Tilly, Anne-Gaëlle Biacabé, Thierry Baron, Jean-Luc Vilotte, Hubert Laude

Publikováno v: PLoS Pathogens, Vol 2, Iss 10, p e112 (2006)

To date, bovine spongiform encephalopathy (BSE) and its human counterpart, variant Creutzfeldt-Jakob disease, have been associated with a single prion strain. This strain is characterised by a unique and remarkably stable biochemical profile of abnor

Externí odkaz: https://doaj.org/article/5eb332d89e1a4a798284ef530a20c8ff

Divergent prion strain evolution driven by PrPC expression level in transgenic mice

Autor: Vincent Béringue, Hubert Laude, Solange Soulier, Bruno Passet, Nathalie Chenais, Sabine Rakotobe, Gaëlle Tilly, Human Rezaei, Laetitia Herzog, Marie-George Stinnakre, Aude Laisné, Jean-Luc Vilotte, Fabienne Reine, Thanh Lan Laï, Annick Le Dur

Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2017, 8, pp.1-11. ⟨10.1038/ncomms14170⟩
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Nature Communications (8), 1-11. (2017)

Prions induce a fatal neurodegenerative disease in infected host brain based on the refolding and aggregation of the host-encoded prion protein PrPC into PrPSc. Structurally distinct PrPSc conformers can give rise to multiple prion strains. Constrain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7987100d3b952864e63a42f979098ccc
https://hal.archives-ouvertes.fr/hal-01605904

Divergent prion strain evolution driven by PrP

Autor: Annick, Le Dur, Thanh Lan, Laï, Marie-George, Stinnakre, Aude, Laisné, Nathalie, Chenais, Sabine, Rakotobe, Bruno, Passet, Fabienne, Reine, Solange, Soulier, Laetitia, Herzog, Gaëlle, Tilly, Human, Rézaei, Vincent, Béringue, Jean-Luc, Vilotte, Hubert, Laude

Publikováno v: Nature Communications

Prions induce a fatal neurodegenerative disease in infected host brain based on the refolding and aggregation of the host-encoded prion protein PrPC into PrPSc. Structurally distinct PrPSc conformers can give rise to multiple prion strains. Constrain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::97bf79790ee7b3956058bb0e466b42af
https://pubmed.ncbi.nlm.nih.gov/28112164

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Isolation from Cattle of a Prion Strain Distinct from That Causing Bovine Spongiform Encephalopathy.

Autor: Béringue, Vincent, Bencsik, Anna, Le Dur, Annick, Reine, Fabienne, Thanh Lan Laï, Chenais, Nathalie, Tilly, Gaëlle, Biacabé, Anne-Gaëlle, Baron, Thierry, Vilotte, Jean-Luc, Laude, Hubert

Publikováno v: PLoS Pathogens; Oct2006, Vol. 2 Issue 10, p0956-0963, 8p