Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Thanh G. Nguyen"'
Autor:
Nag S. Kumar, Thanh G. Nguyen, Suzana Kovacic, Lubomir Vezenkov, Tom A. Pfeifer, Damien Bosc, Nicolette S. Honson, Robert N. Young
Publikováno v:
Bioorganic & Medicinal Chemistry. 23:3237-3247
An efficient assay for monitoring the activity of the key autophagy-initiating enzyme ATG4B based on a small peptide substrate has been developed. A number of putative small fluorogenic peptide substrates were prepared and evaluated and optimized com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89027343307849e60c9066fcc8568611
https://doi.org/10.1016/j.bmc.2015.04.064
https://doi.org/10.1016/j.bmc.2015.04.064
Autor:
Tara L. Davis, Thanh G. Nguyen, Tom A. Pfeifer, Nicolette S. Honson, Nag S. Kumar, Robert N. Young, Suzana Kovacic, Sirano Dhe-Paganon, Steven Arns
Publikováno v:
ASSAY and Drug Development Technologies. 12:176-189
The cysteine protease ATG4B plays a role in key steps of the autophagy process and is of interest as a potential therapeutic target. At an early step, ATG4B cleaves proLC3 isoforms to form LC3-I for subsequent lipidation to form LC3-II and autophagos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7075263ec315b65f948c6419b397552a
https://doi.org/10.1089/adt.2013.561
https://doi.org/10.1089/adt.2013.561