Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Thangavel A, Thanaraj"'
Autor:
Mohammed Dashti, Naser M. Ali, Hussain Alsaleh, Sumi Elsa John, Rasheeba Nizam, Thangavel Alphonse Thanaraj, Fahd Al-Mulla
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
BackgroundNumerous studies have linked mitochondrial dysfunction to the development of type 2 diabetes (T2D) by affecting glucose-stimulated insulin secretion in pancreatic beta cells and reducing oxidative phosphorylation in insulin-responsive tissu
Externí odkaz:
https://doaj.org/article/8f21920e0a8d4429a47384a035bda7bb
Autor:
Mohammed Dashti, Naser M. Ali, Hussain Alsaleh, Sumi Elsa John, Rasheeba Nizam, Fahd Al-Mulla, Thangavel Alphonse Thanaraj
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
BackgroundThe Kuwaiti and Qatari populations have a high prevalence of obesity, a major risk factor for various metabolic disorders. Previous studies have independently explored mitochondrial DNA (mtDNA) variations and their association with obesity
Externí odkaz:
https://doaj.org/article/92b674ae9c274b6d89347513b9c5fc19
Autor:
Rasheeba Nizam, Md Zubbair Malik, Sindhu Jacob, Osama Alsmadi, Heikki A. Koistinen, Jaakko Tuomilehto, Hessa Alkandari, Fahd Al-Mulla, Thangavel Alphonse Thanaraj
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionIncreasing evidence from human and animal model studies indicates the significant role of microRNAs (miRNAs) in pancreatic beta cell function, insulin signaling, immune responses, and pathogenesis of type 1 diabetes (T1D).MethodsWe aimed,
Externí odkaz:
https://doaj.org/article/4ee63224ae1a42cbb189ece9cb942b84
Autor:
Mohammed Dashti, Md Zubbair Malik, Abdullah Al-Matrouk, Saeeda Bhatti, Rasheeba Nizam, Sindhu Jacob, Fahd Al-Mulla, Thangavel Alphonse Thanaraj
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Objective: This study explores the frequency of human leukocyte antigen (HLA) genes, particularly HLA-B alleles, within the Kuwaiti population. We aim to identify alleles with known associations to adverse drug reactions (ADRs) based on existing lite
Externí odkaz:
https://doaj.org/article/52d1ea68d68e4045bef5926ea7ca5cad
Autor:
Khaled Baagar, Thamer Alessa, Mohamed Abu-Farha, Jehad Abubaker, Heba Alhumaidi, Jose Antonio Franco Ceruto, Mohammad Khair Hamad, Ali Omrani, Salma Abdelrahman, Muhammad Zaka-Ul Haq, Abdul Wajid Safi, Bassem Alhariri, Manish Barman, Alaaeldin Abdelmajid, Humberto Vidal Denis Cancio, Eman Elmekaty, Irina Al-Khairi, Preethi Cherian, Lina Jayyousi, Mohammed Ahmed, Mohammed Qaddoumi, Sulaiman Hajji, Ahmad Esmaeel, Ali Al-Andaleeb, Arshad Channanath, Sriraman Devarajan, Hamad Ali, Thangavel Alphonse Thanaraj, Salman Al-Sabah, Fahd Al-Mulla, Muhammad Abdul-Ghani, Amin Jayyousi
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundCoronavirus disease 2019 (COVID-19) caused by the coronavirus SARS-CoV-2, has emerged as a rapidly spreading contagious disease across the globe. Recent studies showed that people with diabetes mellitus, severe obesity, and cardiovascular d
Externí odkaz:
https://doaj.org/article/fcd714fea481423a96ea69231bb1daff
Autor:
Texy Jacob, Sardar Sindhu, Amal Hasan, Md. Zubbair Malik, Hossein Arefanian, Fatema Al-Rashed, Rasheeba Nizam, Shihab Kochumon, Reeby Thomas, Fatemah Bahman, Steve Shenouda, Ajit Wilson, Nadeem Akther, Areej Al-Roub, Nermeen Abukhalaf, Shaima Albeloushi, Mohamed Abu-Farha, Ashraf Al Madhoun, Fawaz Alzaid, Thangavel Alphonse Thanaraj, Heikki A. Koistinen, Jaakko Tuomilehto, Fahd Al-Mulla, Rasheed Ahmad
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
High-fat diets (HFDs) shape the gut microbiome and promote obesity, inflammation, and liver steatosis. Fish and soybean are part of a healthy diet; however, the impact of these fats, in the absence of sucrose, on gut microbial dysbiosis and its assoc
Externí odkaz:
https://doaj.org/article/d3ab3726b78f47ddbc7105c15171b775
Autor:
Mariam E. Alhaddad, Anwar Mohammad, Khadija M. Dashti, Sumi Elsa John, Yousif Bahbahani, Mohamed Abu-Farha, Jehad Abubaker, Thangavel Alphonse Thanaraj, Laila Bastaki, Fahd Al-Mulla, Mohammad Al-Ali, Hamad Ali
Publikováno v:
Heliyon, Vol 10, Iss 13, Pp e33898- (2024)
Background: Autosomal recessive polycystic kidney disease (ARPKD), a rare genetic disorder characterized by kidney cysts, shows complex clinical and genetic heterogeneity. This study aimed to explore the genetic landscape of ARPKD in Kuwait and exami
Externí odkaz:
https://doaj.org/article/1c6d43402608422f869612c63bcc2821
Autor:
Ashwini Kumar Ray, Anjali Priya, Md. Zubbair Malik, Thangavel Alphonse Thanaraj, Alok Kumar Singh, Payal Mago, Chirashree Ghosh, Shalimar, Ravi Tandon, Rupesh Chaturvedi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Cardiovascular disease (CVD) is a collective term for disorders of the heart and blood vessels. The molecular events and biochemical pathways associated with CVD are difficult to study in clinical settings on patients and in vitro conditions
Externí odkaz:
https://doaj.org/article/ae5cf1cc292b4c5a9beba8ec45ed8251
Autor:
Mohammed Dashti, Md Zubbair Malik, Rasheeba Nizam, Sindhu Jacob, Fahd Al-Mulla, Thangavel Alphonse Thanaraj
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Introduction: HLA typing is a critical tool in both clinical and research applications at the individual and population levels. Benchmarking studies have indicated HLA-HD as the preferred tool for accurate and comprehensive HLA allele calling. The ad
Externí odkaz:
https://doaj.org/article/f17211757f174d96acbe76b890d8b8ef
Autor:
Tahani Alramah, Preethi Cherian, Irina Al-Khairi, Mohamed Abu-Farha, Thangavel Alphonse Thanaraj, Ahmed N. Albatineh, Fayez Safadi, Hamad Ali, Muhammad Abdul-Ghani, Jaakko Tuomilehto, Heikki A. Koistinen, Fahd Al-Mulla, Jehad Abubaker
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Obesity and Type 2 Diabetes Mellitus (T2DM) are intricate metabolic disorders with a multifactorial etiology, often leading to a spectrum of complications. Recent research has highlighted the impact of these conditions on bone health, with a particul
Externí odkaz:
https://doaj.org/article/22110a4d4f2b485ea23911df8e8782de