Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Thanemozhi G Natarajan"'
Autor:
Luiz H Araujo, Cynthia Timmers, Konstantin Shilo, Weiqiang Zhao, Jianying Zhang, Lianbo Yu, Thanemozhi G Natarajan, Clinton J Miller, Ayse Selen Yilmaz, Tom Liu, Joseph Amann, José Roberto Lapa E Silva, Carlos Gil Ferreira, David P Carbone
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0143092 (2015)
Tumor specimens are often preserved as formalin-fixed paraffin-embedded (FFPE) tissue blocks, the most common clinical source for DNA sequencing. Herein, we evaluated the effect of pre-sequencing parameters to guide proper sample selection for target
Externí odkaz:
https://doaj.org/article/9c0d6c4bbe984059b2385d1738e3bb68
Autor:
Hayriye Verda Erkizan, Shrey Sukhadia, Thanemozhi G. Natarajan, Gustavo Marino, Vicente Notario, Jack H. Lichy, Robert G. Wadleigh
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Esophageal cancer has a strikingly low survival rate mainly due to the lack of diagnostic markers for early detection and effective therapies. In the U.S., 75% of individuals diagnosed with esophageal squamous cell carcinoma (ESCC) are of Af
Externí odkaz:
https://doaj.org/article/ca8d62a5f3954af2b113cef1574f176b
Autor:
Shrey Sukhadia, Gustavo Marino, Robert G. Wadleigh, Thanemozhi G. Natarajan, Vicente Notario, Hayriye V. Erkizan, Jack H. Lichy
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Esophageal cancer has a strikingly low survival rate mainly due to the lack of diagnostic markers for early detection and effective therapies. In the U.S., 75% of individuals diagnosed with esophageal squamous cell carcinoma (ESCC) are of African des
Publikováno v:
Handbook of Oxidative Stress in Cancer: Mechanistic Aspects ISBN: 9789811545016
Handbook of Oxidative Stress in Cancer: Mechanistic Aspects
Handbook of Oxidative Stress in Cancer: Mechanistic Aspects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::995fb5787396d92f8ab6ad00b27e12d6
https://doi.org/10.1007/978-981-15-4501-6_174-1
https://doi.org/10.1007/978-981-15-4501-6_174-1
Autor:
Audrey A. Ozols, Szabolcs Szelinger, Thanemozhi G. Natarajan, Janine LoBello, Pawan Noel, Laurie J. Goodman, Susan M. Dombrowski, Fadel S. Alyaqoub, Gargi D. Basu, Thomas Royce
Publikováno v:
Journal of Clinical Oncology. 39:109-109
109 Background: Gastrointestinal cancers (GIC) account for 26% of global cancer incidence and 35% of cancer-related deaths. We investigated the molecular landscape and therapeutic targets across 18 types of GIC using whole exome (WES) and whole trans
Autor:
Konstantin Shilo, Ayse Selen Yilmaz, Tom Liu, Philip E. Lammers, David P. Carbone, Thanemozhi G. Natarajan, Rosana Eisenberg, Velmalia Matthews-Smith, Cynthia Timmers, Adriana Gonzalez, Ann G. Schwartz, Luiz H. Araujo, Kevin R. Coombes, Weiqiang Zhao, Jianying Zhang
Publikováno v:
Journal of Thoracic Oncology. 10(10):1430-1436
Introduction: The mutational profile of non–small-cell lung cancer (NSCLC) has become an important tool in tailoring therapy to patients, with clear differences according to the population of origin. African Americans (AAs) have higher lung cancer
Autor:
Weiqiang Zhao, Tom Liu, Cynthia Timmers, Jianying Zhang, Konstantin Shilo, Thanemozhi G. Natarajan, Luiz H. Araujo, Joseph M. Amann, Ayse Selen Yilmaz, David P. Carbone, Philip E. Lammers, Erica Hlavin Bell, Clinton J. Miller, Kevin R. Coombes
Publikováno v:
Journal of Clinical Oncology. 33:1966-1973
Purpose Technologic advances have enabled the comprehensive analysis of genetic perturbations in non–small-cell lung cancer (NSCLC); however, African Americans have often been underrepresented in these studies. This ethnic group has higher lung can
Autor:
Gargi D. Basu, Szabolcs Szelinger, Tracey White, Janine LoBello, Thanemozhi G. Natarajan, Nathan Garinger, Candyce M Bair, Ahmet Kurdoglu, Thomas Royce
Publikováno v:
Journal of Clinical Oncology. 37:e21516-e21516
e21516 Background: With the advent of high-throughput molecular profiling, clinical outcome in pediatric cancers has greatly improved due to our greater understanding of genetic origin of pediatric cancer, and availability of biomarker specific treat
Autor:
Chuming Chen, Cathy H. Wu, Suh Young Jeong, Ronald G. Haller, Sun Young Park, Hongzhan Huang, Thanemozhi G. Natarajan, Wing Hang Tong, Daniel R. Crooks, Tracey A. Rouault, Manik C. Ghosh
Publikováno v:
Human Molecular Genetics. 23:24-39
Iron –s ulfur (Fe-S) clusters are ancient enzyme cofactors found in virtually all life forms. We evaluated the physiological effects of chronic Fe-S cluster deficiency in human skeletal muscle, a tissue that relies heavily on Fe-S cluster-mediated