Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Thaned Kangsamaksin"'
Publikováno v:
Pharmaceuticals, Vol 16, Iss 6, p 902 (2023)
Nasopharyngeal carcinoma (NPC) is a prevalent cancer in Southeast Asia, but effective treatment options remain limited, and chemotherapy has a high resistance rate. Asiatic acid (AA), a triterpenoid found in Centella asiatica, has shown anticancer ac
Externí odkaz:
https://doaj.org/article/ad49f68574044c4d9a7ee7f3b7e5e2ce
Autor:
Nontawat Benjakul, Nattapa Prakobphol, Chayada Tangshewinsirikul, Wirada Dulyaphat, Jisnuson Svasti, Komgrid Charngkaew, Thaned Kangsamaksin
Publikováno v:
PLoS ONE, Vol 17, Iss 12, p e0279001 (2022)
Vasculogenic mimicry (VM) is the process where cancer cells adopt endothelial characteristics by forming tube-like structures and perfusing channels. This phenomenon has been demonstrated in several types of solid tumors and associated with the growt
Externí odkaz:
https://doaj.org/article/616354c6524b4f429a7379708270808e
Autor:
Thaned Kangsamaksin, Supattra Chaithongyot, Chanida Wootthichairangsan, Rattanavinan Hanchaina, Chayada Tangshewinsirikul, Jisnuson Svasti
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189628 (2017)
Lupeol and stigmasterol, major phytosterols in various herbal plants, possess anti-inflammatory activities and have been proposed as candidates for anti-cancer agents, but their molecular mechanisms are still unclear. Here, we investigated the effect
Externí odkaz:
https://doaj.org/article/1ce619703cc740eba42ab0f801abe3b1
Publikováno v:
Pharmaceuticals; Volume 16; Issue 6; Pages: 902
Nasopharyngeal carcinoma (NPC) is a prevalent cancer in Southeast Asia, but effective treatment options remain limited, and chemotherapy has a high resistance rate. Asiatic acid (AA), a triterpenoid found in Centella asiatica, has shown anticancer ac
Autor:
Anuttara Udomprasert, Chanida Wootthichairangsan, Ratchanee Duangrat, Supattra Chaithongyot, Yuwei Zhang, Rachel Nixon, Wenyan Liu, Risheng Wang, Mathurose Ponglikitmongkol, Thaned Kangsamaksin
Publikováno v:
ACS Applied Bio Materials. 5:2262-2272
Previous studies have shown that chemotherapeutic efficacy could be enhanced with targeted drug delivery. Various DNA origami nanostructures have been investigated as drug carriers. Here, we compared drug delivery functionalities of three similar DNA
Autor:
Jan Kitajewski, Carrie J. Shawber, Paul E. Rosenstiel, Ian W. Tattersall, Reyhaan A. Chaudhri, Henar Cuervo, Natalie M. Kofler, Aino Murtomaki, Thaned Kangsamaksin
Figure S1 shows that N11-13 decoy blocks activation of Notch1 by DLL1 but not JAG2 whereas N110-24 decoy blocks activation of Notch1 by JAG2 but not DLL1. Figure S2 shows that purified N11-13 decoy preferentially inhibited DLL4-mediated Notch1 activa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0d13f9b240b3711be0d4a353728e4e9
https://doi.org/10.1158/2159-8290.22529541
https://doi.org/10.1158/2159-8290.22529541
Autor:
Darrell J. Yamashiro, Jessica J. Kandel, Jan K. Kitajewski, Carrie J. Shawber, Angela Kadenhe-Chiweshe, Na Wei, Lynn Ann Forrester, John Andrews, Emily Sbiroli, Thaned Kangsamaksin, Alejandro Garcia, Sonia L. Hernandez, Debarshi Banerjee
Supplementary Figures S1-S12 and Legends. Supplementary Figure S1. Combined Inhibition of Notch and VEGF disrupts interaction of pericytes with endothelial cells in primary tumors Supplementary Figure S2. Inhibition of Notch increases liver metastase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b48c0ffb8d1914832eaa1a5ef52ba056
https://doi.org/10.1158/0008-5472.22406447
https://doi.org/10.1158/0008-5472.22406447
Autor:
Darrell J. Yamashiro, Jessica J. Kandel, Jan K. Kitajewski, Carrie J. Shawber, Angela Kadenhe-Chiweshe, Na Wei, Lynn Ann Forrester, John Andrews, Emily Sbiroli, Thaned Kangsamaksin, Alejandro Garcia, Sonia L. Hernandez, Debarshi Banerjee
The Notch pathway plays multiple key roles in tumorigenesis, and its signaling components have therefore aroused great interest as targets for emerging therapies. Here, we show that inhibition of Notch, using a soluble receptor Notch1 decoy, unexpect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a4c1bfcb541693c573721048a834017
https://doi.org/10.1158/0008-5472.c.6507077
https://doi.org/10.1158/0008-5472.c.6507077
Autor:
Darrell J. Yamashiro, Jessica J. Kandel, Jan K. Kitajewski, Carrie J. Shawber, Angela Kadenhe-Chiweshe, Na Wei, Lynn Ann Forrester, John Andrews, Emily Sbiroli, Thaned Kangsamaksin, Alejandro Garcia, Sonia L. Hernandez, Debarshi Banerjee
Supplementary Table 1. Antibodies utilized in this study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b6386ade79ddeb1f7b4b4d9ea99f078
https://doi.org/10.1158/0008-5472.22406441
https://doi.org/10.1158/0008-5472.22406441
Autor:
Darrell J. Yamashiro, Jessica J. Kandel, Jan K. Kitajewski, Carrie J. Shawber, Angela Kadenhe-Chiweshe, Na Wei, Lynn Ann Forrester, John Andrews, Emily Sbiroli, Thaned Kangsamaksin, Alejandro Garcia, Sonia L. Hernandez, Debarshi Banerjee
Supplementary Methods. Reverse transcription and quantitative PCR. BrdU Proliferation Assay. In vivo BrdU assay. Migration and Invasion Assays. Adenovirus production and Injection. siRNA transfection.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78412beaec8157edc9a03cbd50af5bbc
https://doi.org/10.1158/0008-5472.22406444.v1
https://doi.org/10.1158/0008-5472.22406444.v1