Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Thandokuhle Ntombela"'
Autor:
Zamani E. D. Cele, William Matshe, Lindani Mdlalose, Katlego Setshedi, Kanyane Malatji, Nompumelelo Prudence Mkhwanazi, Thandokuhle Ntombela, Mohammed Balogun
Publikováno v:
ACS Omega, Vol 8, Iss 35, Pp 31714-31724 (2023)
Externí odkaz:
https://doaj.org/article/a741ccf479a84a40b646c307e4fa5ce6
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1506 (2023)
Due to their broad-spectrum activity against Gram-negative and Gram-positive bacteria, natural antimicrobial peptides (AMPs) and their synthetic analogs have emerged as prospective therapies for treating illnesses brought on by multi-drug resistant p
Externí odkaz:
https://doaj.org/article/9aa0455595ca43ce8ae147a487d80bef
Autor:
Nakita Reddy, Letisha Girdhari, Mbongeni Shungube, Arnoldus C. Gouws, Byron K. Peters, Kamal K. Rajbongshi, Sooraj Baijnath, Sipho Mdanda, Thandokuhle Ntombela, Thilona Arumugam, Linda A. Bester, Sanil D. Singh, Anil Chuturgoon, Per I. Arvidsson, Glenn E. M Maguire, Hendrik G. Kruger, Thavendran Govender, Tricia Naicker
Publikováno v:
Antibiotics, Vol 12, Iss 4, p 633 (2023)
Virulent Enterobacterale strains expressing serine and metallo-β-lactamases (MBL) genes have emerged responsible for conferring resistance to hard-to-treat infectious diseases. One strategy that exists is to develop β-lactamase inhibitors to counte
Externí odkaz:
https://doaj.org/article/72015b20994f46ae9bddd7b2baa61e04
Autor:
Aganze G. Mushebenge, Samuel C. Ugbaja, Sphamandla E. Mtambo, Thandokuhle Ntombela, Joy I. Metu, Oludotun Babayemi, Joy I. Chima, Patrick Appiah-Kubi, Adeshina I. Odugbemi, Mthobisi L. Ntuli, Rene Khan, Hezekiel M. Kumalo
Publikováno v:
Molecules, Vol 28, Iss 6, p 2641 (2023)
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for COVID-19, which was declared a global pandemic in March 2020 by the World Health Organization (WHO). Since SARS-CoV-2 main protease plays an essential role in the vir
Externí odkaz:
https://doaj.org/article/18bf8222e4344f97b15aa0942eb9202d
Autor:
Byron K. Peters, Nakita Reddy, Mbongeni Shungube, Letisha Girdhari, Sooraj Baijnath, Sipho Mdanda, Lloyd Chetty, Thandokuhle Ntombela, Thilona Arumugam, Linda A. Bester, Sanil D. Singh, Anil Chuturgoon, Per I. Arvidsson, Glenn E. M. Maguire, Hendrik G. Kruger, Tricia Naicker, Thavendran Govender
Publikováno v:
ACS Infectious Diseases. 9:486-496
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fa25a0f93d4b4812b6db1bfae888f81
https://doi.org/10.1021/acsinfecdis.2c00485
https://doi.org/10.1021/acsinfecdis.2c00485
Autor:
Sibusiso B. Maseko, Yasmine Brammerloo, Inge Van Molle, Adrià Sogues, Charlotte Martin, Christoph Gorgulla, Julien Olivet, Jeremy Blavier, Thandokuhle Ntombela, Frank Delvigne, Haribabu Arthanari, Kourosh Salehi-Ashtiani, Han Remaut, Steven Ballet, Alexander N. Volkov, Jean-Claude Twizere
Human T-cell leukemia virus type-1 (HTLV-1) is the first pathogenic retrovirus discovered in human. Although HTLV-1-induced diseases are well characterized and linked to the encoded Tax-1 oncoprotein, there is currently no strategy to target Tax-1 fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8183a9dedd34e52ff560c8ba47c5c0a8
https://doi.org/10.1101/2023.03.15.532789
https://doi.org/10.1101/2023.03.15.532789
Autor:
Sibusiso B. Maseko, Gyanu Lamichhane, Bahareh Honarparvar, Tricia Naicker, Thavendran Govender, Thandokuhle Ntombela, Glenn E. M. Maguire, Anya Seupersad, Collins U. Ibeji, Gideon F. Tolufashe, Sooraj Baijnath, Hendrik G. Kruger, Siyabonga I. Maphumulo
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 40:7645-7655
Mycobacterium tuberculosis cell wall is intricate and impermeable to many agents. A D, D-carboxypeptidase (DacB1) is one of the enzymes involved in the biosynthesis of cell wall peptidoglycan and catalyzes the terminal D-alanine cleavage from pentape
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b85d2db4030292cc5df2b3ee9a220723
https://doi.org/10.1080/07391102.2021.1899052
https://doi.org/10.1080/07391102.2021.1899052
Autor:
Frédérique Lembo, Charlotte Vandermeulen, Julien Olivet, Aurelie Beauvois, Jeremy Blavier, Haribabu Arthanari, Johan Van Weyenbergh, Franck Dequiedt, Dae-Kyum Kim, Julianne Lim, Stéphanie Skupiewski, Pascale Zimmermann, Malik Hamaidia, Karim Blibek, Deeya Saha, Christoph Gorgulla, Sibusiso B. Maseko, Luc Willems, Inge Van Molle, Alexander N. Volkov, Frank Delvigne, Jean-Claude Twizere, Thandokuhle Ntombela, Jean-Paul Borg
Human T-cell leukemia virus type-1 (HTLV-1) is the first pathogenic retrovirus discovered in human. Although HTLV-1-induced diseases are well characterized and linked to the encoded Tax-1 protein, there is currently no strategy to target Tax-1 functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::339813080b4efa681690bc8dcd02596e
https://doi.org/10.1101/2021.08.25.457680
https://doi.org/10.1101/2021.08.25.457680
Autor:
Gyanu Lamichhane, Collins U. Ibeji, Hendrik G. Kruger, Glenn E. M. Maguire, Thavendran Govender, Bahareh Honarparvar, Monsurat M. Lawal, Gideon F. Tolufashe, Thandokuhle Ntombela, Amit Kumar Halder
Publikováno v:
ChemistrySelect. 3:13603-13612
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::181b23ab6feb9cd445dc35e378261283
https://doi.org/10.1002/slct.201803184
https://doi.org/10.1002/slct.201803184
Autor:
Thandokuhle Ntombela, Collins U. Ibeji, Glenn E. M. Maguire, Gyanu Lamichhane, Thavendran Govender, Hendrik G. Kruger, Gideon F. Tolufashe, Bahareh Honarparvar
Publikováno v:
Tuberculosis. 113:222-230
Mycobacterium tuberculosis is the causative agent of Tuberculosis. Formation of 3 → 3 crosslinks in the peptidoglycan layer of M. tuberculosis is catalyzed by l , d -transpeptidases. These enzymes can confer resistance against classical β-lactams
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2822ba68ceff3efce2edb675460c806
https://doi.org/10.1016/j.tube.2018.10.005
https://doi.org/10.1016/j.tube.2018.10.005