Zobrazeno 1 - 10
of 158
pro vyhledávání: '"Thanasekaran, Jayakumar"'
Autor:
Yi Chang, Chih-Wei Hsia, Kuan-Rau Chiou, Ting-Lin Yen, Thanasekaran Jayakumar, Joen-Rong Sheu, Wei-Chieh Huang
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1689 (2024)
Background: Platelets, a type of anucleated cell, play a crucial role in cardiovascular diseases (CVDs). Therefore, targeting platelet activation is essential for mitigating CVDs. Endogenous agonists, such as collagen, activate platelets by initiatin
Externí odkaz:
https://doaj.org/article/09453405393b47ec91b21a9f5a1f9e29
Autor:
Wei-Chieh Huang, Thanasekaran Jayakumar, Joen-Rong Sheu, Chih-Wei Hsia, Chih-Hsuan Hsia, Ting-Lin Yen, Chao-Chien Chang
Publikováno v:
Chinese Medicine, Vol 18, Iss 1, Pp 1-15 (2023)
Abstract Background Platelets play a crucial role in cardiovascular diseases (CVDs) and are activated by endogenous agonists like collagen. These agonists initiate signal transduction through specific platelet receptors, resulting in platelet aggrega
Externí odkaz:
https://doaj.org/article/08cd4386dd7e433882de1f0309f958d2
Autor:
Yi Chang, Chih-Wei Hsia, Wei-Chieh Huang, Thanasekaran Jayakumar, Chih-Hsuan Hsia, Ting-Lin Yen, Joen-Rong Sheu, Shaw-Min Hou
Publikováno v:
Heliyon, Vol 9, Iss 10, Pp e20286- (2023)
Platelets play a vital role in the formation of dangerous arterial thrombosis. Platelets are activated by adhesive proteins or soluble agonists through their specific receptors. The receptor-mediated signaling pathways lead to common signaling events
Externí odkaz:
https://doaj.org/article/6afe699405ae4e828d1494bec7b1eece
Autor:
Cheng-Ying Hsieh, Thanasekaran Jayakumar, Kao-Chang Lin, Ting-Lin Yen, Chih-Wei Hsia, Wei-Chieh Huang, Joen-Rong Sheu, Chih-Hsuan Hsia
Publikováno v:
European Journal of Inflammation, Vol 21 (2023)
Objectives Oxidative stress induces chronic inflammatory diseases in aerobic organisms, and antioxidants from plants represent an efficient strategy to prevent this condition. Morin hydrate (MH), a bioactive flavonoid, has a wide range of pharmacolog
Externí odkaz:
https://doaj.org/article/10bf0cb55d3b44f3a4efc994c4828a27
Autor:
Shaw-Min Hou, Chih-Wei Hsia, Cheng-Lin Tsai, Chih-Hsuan Hsia, Thanasekaran Jayakumar, Marappan Velusamy, Joen-Rong Sheu
Publikováno v:
Journal of Biomedical Science, Vol 27, Iss 1, Pp 1-14 (2020)
Abstract Background Columbianadin (CBN) is one of the main coumarin constituents isolated from Angelica pubescens. The pharmacological value of CBN is well demonstrated, especially in the prevention of several cancers and analgesic activity. A striki
Externí odkaz:
https://doaj.org/article/a95805c688424ed388ae9b7600b23f2f
Autor:
Joen-Rong Sheu, Cheng-Ying Hsieh, Thanasekaran Jayakumar, Guan-Yi Lin, Hsing-Ni Lee, Shin-Wei Huang, Chih-Hao Yang
Publikováno v:
Journal of Biomedical Science, Vol 26, Iss 1, Pp 1-17 (2019)
Abstract Background Promoting post-stroke neurogenesis has long been proposed to be a therapeutic strategy for the enhancement of functional recovery after cerebral ischemic stroke. Despite numerous approaches have been widely reported the proliferat
Externí odkaz:
https://doaj.org/article/435bba93ea0844958b32ffc6980776ee
Autor:
Thanasekaran Jayakumar, Joen-Rong Sheu
Publikováno v:
Applied Sciences, Vol 12, Iss 16, p 8194 (2022)
Stroke is the second main cause of mortality and morbidity globally [...]
Externí odkaz:
https://doaj.org/article/92f336549ce344a8a4638ed9dda3b12e
Autor:
Thanasekaran Jayakumar, Chun-Jen Huang, Ting-Lin Yen, Chih-Wei Hsia, Joen-Rong Sheu, Periyakali Saravana Bhavan, Wei-Chieh Huang, Cheng-Ying Hsieh, Chih-Hsuan Hsia
Publikováno v:
Molecules, Vol 27, Iss 16, p 5143 (2022)
Inflammation is a major root of several diseases such as allergy, cancer, Alzheimer’s, and several others, and the present state of existing drugs provoked researchers to search for new treatment strategies. Plants are regarded to be unique sources
Externí odkaz:
https://doaj.org/article/95e2c708ba604269b0f18e0e288a6ecc
Autor:
Yi Chang, Wei-Chieh Huang, Chia-Yuan Hsu, Chih-Wei Hsia, Thanasekaran Jayakumar, Cheng-Ying Hsieh, Wan-Jung Lu, Chao-Chien Chang
Publikováno v:
Applied Sciences, Vol 12, Iss 15, p 7426 (2022)
Metformin is widely used as first-line medication for type 2 diabetes (T2D), the main disease comorbid with kidney disease, cardiovascular diseases (CVDs), and retinopathy. Platelets are crucial in platelet-dependent arterial thrombosis, which causes
Externí odkaz:
https://doaj.org/article/05f82dca96554b92a63d7546fafa9f0b
Autor:
Wei-Chieh Huang, Shaw-Min Hou, Ming-Ping Wu, Chih-Wei Hsia, Thanasekaran Jayakumar, Chih-Hsuan Hsia, Periyakali Saravana Bhavan, Chi-Li Chung, Joen-Rong Sheu
Publikováno v:
Molecules, Vol 27, Iss 2, p 476 (2022)
Platelets play a critical role in arterial thrombosis. Rutaecarpine (RUT) was purified from Tetradium ruticarpum, a well-known Chinese medicine. This study examined the relative activity of RUT with NF-κB inhibitors in human platelets. BAY11-7082 (a
Externí odkaz:
https://doaj.org/article/bf18384d6c4d40eb9a4471f83b07b83c