Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Thanaa Mohamed Borg"'
Autor:
Mohammed Fawzy Hamed, Eman Ebrahim El Naggar, Thanaa Mohamed Borg, Ahmed R. El-Sheakh, Elham Abdelmonem Mohamed
Publikováno v:
Drug Design, Development and Therapy. 14:677-696
Background Naringin is a promising anti-inflammatory drug against various disorders including ulcerative colitis. However, its oral bioavailability is low (8%) possibly due to cleavage at the upper gut. Consequently, colon targeting would be necessar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2e9897415ac652faf4cb0363901eb8f
https://doi.org/10.2147/dddt.s218357
https://doi.org/10.2147/dddt.s218357
Publikováno v:
The Foot. 40:14-21
Objective The aim of this study is to develop, and characterize nanostructured lipid carriers (NLCs) of phenytoin (PHT) in order to improve its entrapment efficiency and sustained release to improve the healing process. Methods Twenty-seven patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f89e25df86661f257b99c8d6d56f26bb
https://doi.org/10.1016/j.foot.2019.03.007
https://doi.org/10.1016/j.foot.2019.03.007
Publikováno v:
Drug Development and Industrial Pharmacy. 44:144-157
Phenytoin (PHT) is an antiepileptic drug that was reported to exhibit high wound healing activity. Nevertheless, its limited solubility, bioavailability, and inefficient distribution during topical administration limit its use. Therefore, this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c487485b9a36ef5eea1ba744f5aa0eb9
https://doi.org/10.1080/03639045.2017.1386204
https://doi.org/10.1080/03639045.2017.1386204
Publikováno v:
IOSR Journal of Pharmacy and Biological Sciences. 12:23-29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d59b93b5b29feba17e821ac62a90b765
https://doi.org/10.9790/3008-1202012329
https://doi.org/10.9790/3008-1202012329
Publikováno v:
Pharmaceutical Development and Technology. 22:445-456
The aim of this study is to develop and characterize self-nanoemulsifying drug delivery system (SNEDDS) of piroxicam in liquid and solid forms to improve its dissolution, absorption and therapeutic efficacy.The generation of liquid SNEDDS (L-SNEDDS)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6335ab3148bae69f7a4e5dfdee4c6138
https://doi.org/10.1080/10837450.2016.1231810
https://doi.org/10.1080/10837450.2016.1231810
Autor:
Neal M. Davies, Casey L. Sayre, Connie M. Remsberg, Jody K. Takemoto, Yunqi Zhao, Elham Abdelmonem Mohamed, Thanaa Mohamed Borg, Stephanie E. Martinez, M. Laird Forrest, M. M. Meshali, Abdel Monem M. Foda
Publikováno v:
Journal of Pharmaceutical Sciences. 101:3787-3798
The histone deacetylase inhibitor suberoylanilide hydroxamic acid, known as vorinostat, is a promising anticancer drug with a unique mode of action; however, it is plagued by low water solubility, low permeability, and suboptimal pharmacokinetics. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc00a4fcfe332697182587dd66d3f98d
https://doi.org/10.1002/jps.23265
https://doi.org/10.1002/jps.23265
Publikováno v:
AAPS PharmSciTech. 13:1013-1023
Effects of tromethamine (Tris), polyvinylpyrrolidone (PVP-K25), and low molecular weight chitosan (LM-CH) on dissolution and therapeutic efficacy of glimepiride (Gmp) were investigated using physical mixtures (PMs), coground mixtures, coprecipitates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9c4fd39259bd7c92d9f339ab4033b23
https://doi.org/10.1208/s12249-012-9812-5
https://doi.org/10.1208/s12249-012-9812-5
Autor:
Taishi Higashi, Keiichi Motoyama, Irhan Ibrahim Abu Hashim, Thanaa Mohamed Borg, Abd ElGawad Helmy Abd-ElGawad, Takayuki Anno, Hidetoshi Arima, Mohamed H. El-Shabouri
Publikováno v:
International Journal of Pharmaceutics. 392:83-91
The development of injectable hydrogels for protein delivery is a major challenge. In this study, insulin/alpha-cyclodextrin (alpha-CyD) and gamma-CyD polypseudorotaxane (PPRX) hydrogels were prepared through inclusion complexation between high molec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70ce0812f418560d78b3bded8e2690da
https://doi.org/10.1016/j.ijpharm.2010.03.026
https://doi.org/10.1016/j.ijpharm.2010.03.026
Autor:
Thanaa Mohamed Borg, Connie M. Remsberg, Casey L. Sayre, Abdel Monem M. Foda, Elham Abdelmonem Mohamed, Stephanie E. Martinez, Jody K. Takemoto, Neal M. Davies, M. M. Meshali
Publikováno v:
Journal of Chromatography & Separation Techniques.
The utility of currently reported liquid chromatography mass spectrometry methods for quantitation of vorinostat in plasma or serum may be limited. These methods employ time consuming and expensive procedures such as solid phase extraction or limited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22b3932c8107058adff16f90b8713d46
https://doi.org/10.4172/2157-7064.1000118
https://doi.org/10.4172/2157-7064.1000118
Autor:
Hidetoshi Arima, Mohamed H. El-Shabouri, Keiichi Motoyama, Irhan Ibrahim Abu Hashim, Abd ElGawad Helmy Abd-ElGawad, Thanaa Mohamed Borg
Publikováno v:
International journal of pharmaceutics. 393(1-2)
Topical application of nuclear factor-kappaB (NF-kappaB) decoy appears to provide a novel therapeutic potency in the treatment of inflammation and atopic dermatitis. However, it is difficult to deliver NF-kappaB decoy oligonucleotides (ODN) into the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf31874c29fd30720f32e9877092ea7e
https://pubmed.ncbi.nlm.nih.gov/20417264
https://pubmed.ncbi.nlm.nih.gov/20417264