Výsledky vyhledávání - "Thamizh K. Nithy"

Early pregnancy induced expression of prostaglandin E2 receptors EP2 and EP4 in the ovine endometrium and regulated by interferon tau through multiple cell signaling pathways

Autor: Joe A. Arosh, Sakhila K. Banu, Jone A. Stanley, Thamizh K. Nithy, JeHoon Lee

Publikováno v: Molecular and Cellular Endocrinology. 348:211-223

Prostaglandin E2 (PGE(2)) plays pleiotropic roles at fetal-maternal interface during establishment of pregnancy. The objectives of the study were to: (i) determine regulation of PGE2 receptors EP1, EP2, EP3, and EP4 in the endometrium during the estr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9620b0cedf7b67925b85cb53fcd2209a
https://doi.org/10.1016/j.mce.2011.08.020

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Chromium-VI arrests cell cycle and decreases granulosa cell proliferation by down-regulating cyclin-dependent kinases (CDK) and cyclins and up-regulating CDK-inhibitors

Autor: JeHoon Lee, Thamizh K. Nithy, Sakhila K. Banu, Robert C. Burghardt, Jone A. Stanley, Joe A. Arosh

Publikováno v: Reproductive Toxicology. 32:112-123

Environmental contamination with hexavalent chromium (CrVI) has been increasing in the drinking water of the USA and developing countries. CrVI causes various health problems including menstrual disorders and infertility. Recently, we reported that C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07c62509ce4ab9dbe4781c3f2f484e20
https://doi.org/10.1016/j.reprotox.2011.05.007

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Postnatal exposure to chromium through mother’s milk accelerates follicular atresia in F1 offspring through increased oxidative stress and depletion of antioxidant enzymes

Autor: Joe A. Arosh, Robert C. Burghardt, Sakhila K. Banu, Patricia B. Hoyer, Thamizh K. Nithy, Jone A. Stanley, Kirthiram K. Sivakumar

Hexavalent chromium, CrVI, is a heavy metal endocrine disruptor, known as a mutagen, teratogen, and a group A carcinogen. Environmental contamination with CrVI, including drinking water, has been increasing in more than 30 cities in the United States

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9be4414351f3a8dc7544404df3f2ece2
https://europepmc.org/articles/PMC3883978/

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Intraluteal Prostaglandin Biosynthesis and Signaling Are Selectively Directed Towards PGF2alpha During Luteolysis but Towards PGE2 During the Establishment of Pregnancy in Sheep1

Autor: JeHoon Lee, Sakhila K. Banu, John A. McCracken, Jone A. Stanley, Joe A. Arosh, Thamizh K. Nithy

Publikováno v: Biology of Reproduction. 87

In ruminants, endometrial prostalgandin (PG) F(2alpha) causes functional luteolysis, whereas luteal synthesis of PGF(2alpha) is required for structural luteolysis. PGE(2) is considered to be a luteoprotective mediator. Molecular aspects of luteal PGF

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::da16783816fb3d2570711b5bded8643f
https://doi.org/10.1095/biolreprod.112.100438

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Intraluteal prostaglandin biosynthesis and signaling are selectively directed towards PGF2alpha during luteolysis but towards PGE2 during the establishment of pregnancy in sheep

Autor: JeHoon, Lee, John A, McCracken, Jone A, Stanley, Thamizh K, Nithy, Sakhila K, Banu, Joe A, Arosh

Publikováno v: Biology of reproduction. 87(4)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7b0ea53361cf4029bd29d00cee263fd0
https://pubmed.ncbi.nlm.nih.gov/22743300

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Interferon tau regulates PGF2alpha release from the ovine endometrial epithelial cells via activation of novel JAK/EGFR/ERK/EGR-1 pathways

Autor: Sakhila K. Banu, Joe A. Arosh, JeHoon Lee, Sam D. Stephen, Thamizh K. Nithy

Publikováno v: Molecular endocrinology (Baltimore, Md.). 24(12)

In ruminants, pulsatile release of prostaglandin F2α (PGF2α) from the endometrium is transported to the ovary and induces luteolysis thereby allowing new estrous cycle. Interferon tau (IFNT), a type 1 IFN secreted by the trophoblast cells of the de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b0b29cf11478c3b1124e16efbeebc74
https://pubmed.ncbi.nlm.nih.gov/20962043

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Transport of prostaglandin F(2alpha) pulses from the uterus to the ovary at the time of luteolysis in ruminants is regulated by prostaglandin transporter-mediated mechanisms

Autor: Joe A. Arosh, Thamizh K. Nithy, Sakhila K. Banu, Royce Rodriguez, John A. McCracken, JeHoon Lee

Publikováno v: Endocrinology. 151(7)

In ruminants, prostaglandin F2alpha (PGF(2alpha)) is the uterine luteolytic hormone. During luteolysis, PGF(2alpha) is synthesized and released from the endometrium in a pulsatile pattern. The unique structure of the vascular utero-ovarian plexus (UO

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc0202310fc6fc103011b38a746868ec
https://pubmed.ncbi.nlm.nih.gov/20410207

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