Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Thamaraiselvi Saravanan"'
Autor:
Urikhan Sanzhaeva, Helen Boyd-Pratt, Philip T. R. Bender, Thamaraiselvi Saravanan, Scott B. Rhodes, Tongju Guan, Neil Billington, Shannon E. Boye, Christopher L. Cunningham, Charles T. Anderson, Visvanathan Ramamurthy
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-18 (2024)
Abstract Microtubules are essential for various cellular processes. The functional diversity of microtubules is attributed to the incorporation of various α- and β-tubulin isotypes encoded by different genes. In this work, we investigated the funct
Externí odkaz:
https://doaj.org/article/2bce1a002054404696b0451fc39c920b
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Prominin 1 (PROM1) is a pentaspan transmembrane glycoprotein localized on the nascent photoreceptor discs. Mutations in PROM1 are linked to various retinal diseases. In this study, we assessed the role of PROM1 in photoreceptor biology and p
Externí odkaz:
https://doaj.org/article/8279a39f068b49c4bea5da400431c024
Autor:
Daniella Munezero, Hunter Aliff, Ezequiel Salido, Thamaraiselvi Saravanan, Urikhan Sanzhaeva, Tongju Guan, Visvanathan Ramamurthy
Publikováno v:
Journal of Biological Chemistry. :104809
Autor:
Daniella Munezero, Visvanathan Ramamurthy, Jesse Sundar, Thamaraiselvi Saravanan, Caitlyn Bryan-Haring, Angelica Jacques
Publikováno v:
Hum Mol Genet
Retinitis pigmentosa (RP) is a debilitating blinding disease affecting over 1.5 million people worldwide, but the mechanisms underlying this disease are not well understood. One of the common models used to study RP is the retinal degeneration-10 (rd
Autor:
Abigail R. Moye, Ratnesh K. Singh, Tanya L. Dilan, Peter Stoilov, Thamaraiselvi Saravanan, Visvanathan Ramamurthy, Andrew F.X. Goldberg
Publikováno v:
Human Molecular Genetics. 27:283-294
Bardet-Biedl syndrome (BBS) is an autosomal recessive ciliopathy characterized by developmental abnormalities and vision loss. To date, mutations in 21 genes have been linked to BBS. The products of eight of these BBS genes form a stable octameric co
Autor:
Ezequiel M. Salido, Thamaraiselvi Saravanan, Abigail R. Moye, Tanya L. Dilan, Andrew F.X. Goldberg, Visvanathan Ramamurthy, Saravanan Kolandaivelu
Mutations in the Joubert syndrome-associated small GTPase ARL13B are linked to photoreceptor impairment and vision loss. To determine the role of ARL13B in the development, function, and maintenance of ciliated photoreceptors, we generated a pan-reti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79db1fa7a6211c806477dce241bcb2c1
https://europepmc.org/articles/PMC6381253/
https://europepmc.org/articles/PMC6381253/
Autor:
Andrew F.X. Goldberg, Tanya L. Dilan, Abigail R. Moye, Ratnesh K. Singh, Victoria A. Kimler, Visvanathan Ramamurthy, Daniella Munezero, Thamaraiselvi Saravanan
Publikováno v:
Molecular biology of the cell. 29(13)
The outer segment (OS) of photoreceptor cells is an elaboration of a primary cilium with organized stacks of membranous disks that contain the proteins needed for phototransduction and vision. Though ciliary formation and function has been well chara