Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Thamarai Schneiders"'
Autor:
Juan-Carlos Jiménez-Castellanos, Bartlomiej Waclaw, Alison Meynert, Sean P. McAteer, Thamarai Schneiders
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Colistin remains an important antibiotic for the therapeutic management of drug-resistant Klebsiella pneumoniae. Despite the numerous reports of colistin resistance in clinical strains, it remains unclear exactly when and how different mutat
Externí odkaz:
https://doaj.org/article/e7fedae6697e41a6b06a1e6a8797ff17
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Externí odkaz:
https://doaj.org/article/82affbebe95f4a1184f39002d8d1222a
Autor:
Shyamasree De Majumdar, Jing Yu, Maria Fookes, Sean P McAteer, Enrique Llobet, Sarah Finn Shaun Spence, Avril Monaghan, Adrien Kissenpfennig, Rebecca J Ingram, José Bengoechea, David L Gally, Séamus Fanning, Joseph S Elborn, Thamarai Schneiders
Publikováno v:
PLoS Pathogens, Vol 12, Iss 5, p e1005649 (2016)
[This corrects the article DOI: 10.1371/journal.ppat.1004627.].
Externí odkaz:
https://doaj.org/article/98ac0e0b6f46457f9ef961859eb38995
Autor:
Shyamasree De Majumdar, Jing Yu, Maria Fookes, Sean P McAteer, Enrique Llobet, Sarah Finn, Shaun Spence, Avril Monahan, Avril Monaghan, Adrien Kissenpfennig, Rebecca J Ingram, José Bengoechea, David L Gally, Séamus Fanning, Joseph S Elborn, Thamarai Schneiders
Publikováno v:
PLoS Pathogens, Vol 11, Iss 1, p e1004627 (2015)
Klebsiella pneumoniae is a significant human pathogen, in part due to high rates of multidrug resistance. RamA is an intrinsic regulator in K. pneumoniae established to be important for the bacterial response to antimicrobial challenge; however, litt
Externí odkaz:
https://doaj.org/article/d280d78a40a04c13b06cf48c876f1155
SynopsisObjectivesWe seek to understand the dynamics of de novo resistant mutations arising during colistin treatment of an antibiotic-naïve population of K. pneumoniae.MethodsWe used a bioreactor model of infection and colistin treatment against th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e67bb35f6c56c7265577dbf017d0cfb
https://doi.org/10.1101/2022.10.03.510619
https://doi.org/10.1101/2022.10.03.510619
Autor:
Kristian Alfsnes, Lucy van Dorp, Thamarai Schneiders, Francois Balloux, Dominique A. Caugant, Ola Brønstad Brynildsrud, Kate Templeton, Vegard Eldholm, Koji Yahara, Magnus N Osnes
Publikováno v:
Osnes, M N, van Dorp, L, Brynildsrud, O B, Alfsnes, K, Schneiders, T, Templeton, K, Yahara, K, Balloux, F, Caugant, D A & Eldholm, V 2020, ' Antibiotic treatment regimes as a driver of the global population dynamics of a major gonorrhea lineage ', Molecular Biology and Evolution, vol. 38, no. 4, pp. 1249–1261 . https://doi.org/10.1093/molbev/msaa282
Molecular Biology and Evolution
Molecular biology and evolution
Molecular Biology and Evolution
Molecular biology and evolution
The Neisseria gonorrhoeae multilocus sequence type (ST) 1901 is among the lineages most commonly associated with treatment failure. Here, we analyze a global collection of ST-1901 genomes to shed light on the emergence and spread of alleles associate
Autor:
Magnus N Osnes, Lucy van Dorp, Ola B Brynildsrud, Kristian Alfsnes, Thamarai Schneiders, Kate E Templeton, Koji Yahara, Francois Balloux, Dominique A Caugant, Vegard Eldholm
Publikováno v:
Molecular Biology and Evolution
The Neisseria gonorrhoeae multilocus sequence type (ST) 1901 is among the lineages most commonly associated with treatment failure. Here, we analyze a global collection of ST-1901 genomes to shed light on the emergence and spread of alleles associate
Autor:
Kate J. Heesom, Juan-Carlos Jiménez-Castellanos, Matthew B. Avison, Jacqueline Findlay, Yuiko Takebayashi, Wan Ahmad Kamil Wan Nur Ismah, Thamarai Schneiders
Publikováno v:
Jiménez-Castellanos, J-C, Wan Ahmad Kamil, W N I, Takebayashi, Y, Findlay, J, Schneiders, T, Heesom, K J & Avison, M B 2018, ' Envelope proteome changes driven by RamA overproduction in Klebsiella pneumoniae that enhance acquired β-lactam resistance ', Journal of Antimicrobial Chemotherapy, vol. 73, no. 1, dkx345, pp. 88-94 . https://doi.org/10.1093/jac/dkx345
Objectives: In Klebsiella pneumoniae, overproduction of RamA results in reduced envelope permeability and reduced antimicrobial susceptibility but clinically relevant resistance is rarely observed. Here we have tested whether RamA overproduction can
Autor:
Paweł Sacha, Thamarai Schneiders, Jacek Niklinski, Piotr Wieczorek, Paulina Majewska, Agnieszka Zebrowska, Dominika Ojdana, Piotr Majewski, Anna Gutowska, Oksana Kowalczuk, Mariola Talalaj, Piotr Radziwon, Elzbieta Tryniszewska, Tomasz Hauschild
Publikováno v:
The Journal of antimicrobial chemotherapy. 75(5)
Background The growing incidence of MDR Gram-negative bacteria is a rapidly emerging challenge in modern medicine. Objectives We sought to establish the role of intrinsic drug-resistance regulators in combination with specific genetic mutations in 11
Publikováno v:
Antimicrobial Agents and Chemotherapy. 60:1085-1090
Overexpression of the resistance-nodulation-cell division-type efflux pump AdeABC is often associated with multidrug resistance in Acinetobacter baumannii and has been linked to mutations in the genes encoding the AdeRS two-component system. In a pre