Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Tham M. Yao"'
Autor:
Burhanuddin Moize, Elijah Trefts, Tham M. Yao, Rene Baudrand, Sanjay Ranjit, Gail K. Adler, Thitinan Treesaranuwattana, Isis Katayama Rangel, Luminita H. Pojoga, Amanda E Garza, Jose R. Romero, Gordon H. Williams, Danielle L Brooks
Publikováno v:
The Journal of Endocrinology
Aldosterone modulates the activity of both epithelial (specifically renal) and non-epithelial cells. Binding to the mineralocorticoid receptor (MR), activates two pathways: the classical genomic and the rapidly activated non-genomic that is substanti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e3be07f37df81e640130b7d0d5e8bad
https://doi.org/10.1530/joe-19-0562
https://doi.org/10.1530/joe-19-0562
Autor:
Anis Amalina Abdul Hamid, Luminita H. Pojoga, Gordon H. Williams, Amanda E Garza, Cherish Chong, Jose R. Romero, Gail K. Adler, Tham M. Yao
Publikováno v:
Journal of Endocrinology. 232:525-534
We posit the existence of a paracrine/autocrine negative feedback loop, mediated by the mineralocorticoid receptor (MR), regulating aldosterone secretion. To assess this hypothesis, we asked whether altering MR activity in zona glomerulosa (ZG) cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65469307994533e0df4bed952809d63a
https://doi.org/10.1530/joe-16-0452
https://doi.org/10.1530/joe-16-0452
Autor:
Gail K. Adler, Pei Yee Ting, Yuefei Huang, Jonathan S. Williams, Tsuyoshi Homma, Luminita H. Pojoga, Gordon H. Williams, Danielle L Brooks, Jose R. Romero, Isis Katayama Rangel, Tham M. Yao
Publikováno v:
The Journal of endocrinology. 240(2)
Human risk allele carriers of lysine-specific demethylase 1 (LSD1) and LSD1-deficient mice have salt-sensitive hypertension for unclear reasons. We hypothesized that LSD1 deficiency causes dysregulation of aldosterone’s response to salt intake resu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c6fb26076fbaa039e589bbfadad0a8f
https://pubmed.ncbi.nlm.nih.gov/30400034
https://pubmed.ncbi.nlm.nih.gov/30400034
Autor:
Ossama M. Reslan, Luminita H. Pojoga, Lauren A. Opsasnick, Gordon H. Williams, Waleed T. Siddiqui, Raouf A. Khalil, Tham M. Yao, Gail K. Adler
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 355:32-47
Aldosterone interacts with mineralocorticoid receptor (MR) to stimulate sodium reabsorption in renal tubules and may also affect the vasculature. Caveolin-1 (cav-1), an anchoring protein in plasmalemmal caveolae, binds steroid receptors and also endo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ca4e888166f17e771fbe3d9d434e372
https://doi.org/10.1124/jpet.115.226043
https://doi.org/10.1124/jpet.115.226043
Autor:
Burhanuddin Moize, Jessica Lasky-Su, Gordon H. Williams, Jose R. Romero, Rene Baudrand, Gail K. Adler, Bei Sun, Jonathan S. Williams, Luminita H. Pojoga, Chevon M. Rariy, Wan M. Hafiz, Amanda E Garza, Claudio Ferri, Tham M. Yao, Paul N. Hopkins
Publikováno v:
Hypertension. 65:211-217
Striatin is a novel protein that interacts with steroid receptors and modifies rapid, nongenomic activity in vitro. We tested the hypothesis that striatin would in turn affect mineralocorticoid receptor function and consequently sodium, water, and bl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea2557d6ceccb17a283530b6ccd2b249
https://doi.org/10.1161/hypertensionaha.114.04233
https://doi.org/10.1161/hypertensionaha.114.04233
Autor:
Jose R. Romero, Gail K. Adler, Gordon H. Williams, Korapat Mayurasakorn, Anis Amalina Abdul Hamid, Yuefei Huang, Nurul Mahamad Rodi, Mika Homma, Tsuyoshi Homma, Luminita H. Pojoga, Shelley Hurwitz, Tham M. Yao
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background We hypothesized that caloric restriction ( CR ) and salt restriction (ResS) would have similar effects on reducing cardiovascular risk markers and that combining CR and ResS would be synergistic in modulating these markers. Methods and Res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6a00640c64a17c25b27525d040ac9af
https://pubmed.ncbi.nlm.nih.gov/29021272
https://pubmed.ncbi.nlm.nih.gov/29021272
Autor:
Raouf A. Khalil, Gordon H. Williams, Gail K. Adler, Amanda E Garza, Tham M. Yao, Ossama M. Reslan, Luminita H. Pojoga, Lauren A. Opsasnick
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 348:260-270
Hyperglycemia and endothelial dysfunction are associated with hypertension, but the specific causality and genetic underpinning are unclear. Caveolin-1 (cav-1) is a plasmalemmal anchoring protein and modulator of vascular function and glucose homeost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da5ba7f94efaf951674b82b23b0a066d
https://doi.org/10.1124/jpet.113.209189
https://doi.org/10.1124/jpet.113.209189
Autor:
Pei Yee Ting, Luminita H. Pojoga, Tham M. Yao, Jia Wei Tan, Gail K. Adler, Amanda E Garza, Jose R. Romero, Yuefei Huang, Isis Katayama Rangel, Paul Loutraris, Gordon H. Williams
Publikováno v:
Hypertension. 68
Lysine-Specific Demethylase1 (LSD1) is an epigenetic factor modulated by salt intake. Previously, we documented the male heterozygote LSD1 knockout mice (LSD1+/-) had dysregulation of aldosterone (ALDO) production on a liberal salt diet (1.6% Na+) as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da8dd8a57ddeaaed37a151741ff07d4a
https://doi.org/10.1161/hyp.68.suppl_1.097
https://doi.org/10.1161/hyp.68.suppl_1.097
Autor:
Tham M. Yao, Xavier Jeunemaitre, Rene Baudrand, Anand Vaidya, Gail K. Adler, Gordon H. Williams, Paul A. Vöhringer, Amanda E Garza, Luminita H. Pojoga, Jonathan S. Williams, Paul N. Hopkins
Publikováno v:
Circulation. 133
We thank Dr Campbell for his interest in our study,1 and the fair and helpful comments from the accompanying editorial by Andersson and Vasan, as well.2 We are in agreement with Dr Campbell that statins may influence adrenal steroidogenesis via a mul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af268c7bf9d2efba8366fe0921bde6d2
https://doi.org/10.1161/circulationaha.116.021486
https://doi.org/10.1161/circulationaha.116.021486
Autor:
Patricia Coutinho, Gordon H. Williams, Christine Guo, Jose R. Romero, Gail K. Adler, Tham M. Yao, Bill Q. Lian, Jianmin Li, Vincent Ricchiuti
Publikováno v:
Circulation. 117:2253-2261
Background— In obesity, decreases in adiponectin and increases in proinflammatory adipokines are associated with heart disease. Because adipocytes express mineralocorticoid receptor (MR) and MR blockade reduces cardiovascular inflammation and injur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cdfe76e175b828d9656ca8da8111b496
https://doi.org/10.1161/circulationaha.107.748640
https://doi.org/10.1161/circulationaha.107.748640