Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Thallapuranam Krishnaswamy Suresh Kumar"'
Autor:
Phuc Phan, Anant Deshwal, Tyler Anthony McMahon, Matthew Slikas, Elodie Andrews, Brian Becker, Thallapuranam Krishnaswamy Suresh Kumar
Publikováno v:
Toxins, Vol 16, Iss 1, p 2 (2023)
Venom components are invaluable in biomedical research owing to their specificity and potency. Many of these components exist in two genera of rattlesnakes, Crotalus and Sistrurus, with high toxicity and proteolytic activity variation. This review fo
Externí odkaz:
https://doaj.org/article/3ddbb281d89b4c3f9a428f1d20e65165
Autor:
Shilpi Agrawal, Vivek Govind Kumar, Ravi Kumar Gundampati, Mahmoud Moradi, Thallapuranam Krishnaswamy Suresh Kumar
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Human acidic fibroblast growth factor (hFGF1) is an all beta-sheet protein that is involved in the regulation of key cellular processes including cell proliferation and wound healing. hFGF1 is known to aggregate when subjected to thermal unf
Externí odkaz:
https://doaj.org/article/005e77758849402eabcccf23b28c49d7
Autor:
Adil S. Al-Ogaili, Rohana Liyanage, Jack O. Lay, Tieshan Jiang, Christine N. Vuong, Shilpi Agrawal, Thallapuranam Krishnaswamy Suresh Kumar, Luc R. Berghman, Billy M. Hargis, Young Min Kwon
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract Several agonists to CD40 have shown to induce acquired immune responses. Here, we developed and evaluated the rolling circle amplification (RCA) products that are based on anti-CD40 DNA aptamers as a novel vaccine adjuvant. First, we develop
Externí odkaz:
https://doaj.org/article/22abb468b59f435eb360b09b8463f8c6
Autor:
Julie Eberle Davis, Ravi Kumar Gundampati, Srinivas Jayanthi, Joshua Anderson, Abigail Pickhardt, Bhanu prasanth Koppolu, David A. Zaharoff, Thallapuranam Krishnaswamy Suresh Kumar
Publikováno v:
Biochemistry and Biophysics Reports, Vol 13, Iss , Pp 45-57 (2018)
Acidic human fibroblast growth factor (hFGF1) plays a key role in cell growth and proliferation. Activation of the cell surface FGF receptor is believed to involve the glycosaminoglycan, heparin. However, the exact role of heparin is a subject of con
Externí odkaz:
https://doaj.org/article/8e6c0f7814af4fd0a6fcb6fb12ad3479
Autor:
Phuc Phan, Bibhuti Ballav Saikia, Shivakumar Sonnaila, Shilpi Agrawal, Zeina Alraawi, Thallapuranam Krishnaswamy Suresh Kumar, Shilpa Iyer
Publikováno v:
Cells, Vol 10, Iss 9, p 2418 (2021)
Fibroblast growth factors (FGFs) are cell-signaling proteins with diverse functions in cell development, repair, and metabolism. The human FGF family consists of 22 structurally related members, which can be classified into three separate groups base
Externí odkaz:
https://doaj.org/article/5e20eddc512d4787b60487158453204d
Autor:
Srinivas Jayanthi, Bhanu prasanth Koppolu, Khue G. Nguyen, Sean G. Smith, Barbara K. Felber, Thallapuranam Krishnaswamy Suresh Kumar, David A. Zaharoff
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Glycosaminoglycans (GAGs), especially heparin and heparan sulfate (HS), modulate the functions of numerous cytokines. The aims of this multidisciplinary research were to characterize heparin binding to interleukin-12 (IL-12) and determine th
Externí odkaz:
https://doaj.org/article/e144fa0271714f01b788c20adf60ba9f
Autor:
Vivek Govind Kumar, Adithya Polasa, Shilpi Agrawal, Thallapuranam Krishnaswamy Suresh Kumar, Mahmoud Moradi
Publikováno v:
Nature Computational Science. 3:59-70
The protein–ligand binding affinity quantifies the binding strength between a protein and its ligand. Computer modeling and simulations can be used to estimate the binding affinity or binding free energy using data- or physics-driven methods or a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb55cdbfc43748c351add150cfc677c8
https://doi.org/10.1038/s43588-022-00389-9
https://doi.org/10.1038/s43588-022-00389-9
Autor:
Patience Salvalina Okoto, Shivakumar Sonniala, Beatrice Sakhel, Djamali Muhoza, Paul Adams, Thallapuranam Krishnaswamy Suresh Kumar
Publikováno v:
Methods in Molecular Biology ISBN: 9781071631461
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80e0af21c8e6a78d549001850726a9c3
https://doi.org/10.1007/978-1-0716-3147-8_8
https://doi.org/10.1007/978-1-0716-3147-8_8
Publikováno v:
The Journal of Physical Chemistry B. 125:12690-12697
Human fibroblast growth factor (FGF) 1 or hFGF1 is a member of the FGF family that isare involved in various vital processes such as cell proliferation, cell differentiation, angiogenesis and wound healing. hFGF1, which is associated with low stabili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00319da4c334006c7411b8e55fb0278f
https://doi.org/10.1021/acs.jpcb.1c07772
https://doi.org/10.1021/acs.jpcb.1c07772
Publikováno v:
International journal of molecular sciences. 23(22)
The study of protein aggregation, and amyloidosis in particular, has gained considerable interest in recent times. Several neurodegenerative diseases, such as Alzheimer’s (AD) and Parkinson’s (PD) show a characteristic buildup of proteinaceous ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a6f59cbd9191aacc4a2e78b3ad650f
https://pubmed.ncbi.nlm.nih.gov/36430450
https://pubmed.ncbi.nlm.nih.gov/36430450