White Button Mushroom (Agaricus bisporus) Supplementation Ameliorates Spatial Memory Deficits and Plaque Formation in an Amyloid Precursor Protein Mouse Model of Alzheimer’s Disease

Autor: Thalia T. Dimopoulos, Stephen L. P. Lippi, Jorge Fernandez Davila, Rachel E. Barkey, Erin N. Doherty, Jane M. Flinn

Publikováno v: Brain Sciences, Vol 12, Iss 10, p 1364 (2022)

Alzheimer’s Disease (AD) is characterized by cognitive impairment and the presence of amyloid-β (Aβ) plaques and tau tangles. This study was conducted to assess the effects of white button mushroom (WBM) supplementation on spatial memory and plaq

Externí odkaz: https://doaj.org/article/361fbefc9bef46868845152ed52b17a9

Activation of alveolar epithelial ER stress by β-coronavirus infection disrupts surfactant homeostasis in mice: implications for COVID-19 respiratory failure.

Autor: Murthy A; Pulmonary and Critical Care Division, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States.; PENN-CHOP Lung Biology Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States., Rodriguez LR; Pulmonary and Critical Care Division, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States.; PENN-CHOP Lung Biology Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States., Dimopoulos T; Pulmonary and Critical Care Division, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States., Bui S; Pulmonary and Critical Care Division, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States.; PENN-CHOP Lung Biology Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States., Iyer S; Pulmonary and Critical Care Division, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States., Chavez K; Pulmonary and Critical Care Division, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States., Tomer Y; Pulmonary and Critical Care Division, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States., Abraham V; Pulmonary and Critical Care Division, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States., Cooper C; Pulmonary and Critical Care Division, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States., Renner DM; Department of Microbiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States.; Penn Center for Research on Coronaviruses and Emerging Pathogens, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States., Katzen JB; Pulmonary and Critical Care Division, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States.; PENN-CHOP Lung Biology Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States., Bentley ID; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio, United States., Ghadiali SN; Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio, United States.; Department of Biomedical Engineering, The Ohio State University Wexner Medical Center, Columbus, Ohio, United States., Englert JA; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio, United States., Weiss SR; Department of Microbiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States.; Penn Center for Research on Coronaviruses and Emerging Pathogens, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States., Beers MF; Pulmonary and Critical Care Division, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States.; PENN-CHOP Lung Biology Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States.

Publikováno v: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2024 Aug 01; Vol. 327 (2), pp. L232-L249. Date of Electronic Publication: 2024 Jun 11.

Chronic Expression of a Clinical SFTPC Mutation Causes Murine Lung Fibrosis with Idiopathic Pulmonary Fibrosis Features.

Autor: Rodriguez L; Pulmonary, Allergy, and Critical Care Medicine Division and., Tomer Y; Pulmonary, Allergy, and Critical Care Medicine Division and., Carson P; Pulmonary, Allergy, and Critical Care Medicine Division and., Dimopoulos T; Pulmonary, Allergy, and Critical Care Medicine Division and., Zhao M; Pulmonary, Allergy, and Critical Care Medicine Division and., Chavez K; Pulmonary, Allergy, and Critical Care Medicine Division and., Iyer S; Pulmonary, Allergy, and Critical Care Medicine Division and., Huang L; Fibrosis Biology Drug Discovery, Bristol-Myers Squibb, Lawrenceville, New Jersey; and., Ebert C; Fibrosis Biology Drug Discovery, Bristol-Myers Squibb, Lawrenceville, New Jersey; and., Sereda L; Fibrosis Biology Drug Discovery, Bristol-Myers Squibb, Lawrenceville, New Jersey; and., Murthy A; Pulmonary, Allergy, and Critical Care Medicine Division and., Trujillo G; Fibrosis Biology Drug Discovery, Bristol-Myers Squibb, Lawrenceville, New Jersey; and., Beers MF; Pulmonary, Allergy, and Critical Care Medicine Division and.; PENN-CHOP Lung Biology Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.; The Michael Crescenz VA Medical Center, Philadelphia, Pennsylvania., Katzen J; Pulmonary, Allergy, and Critical Care Medicine Division and.; PENN-CHOP Lung Biology Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.

Publikováno v: American journal of respiratory cell and molecular biology [Am J Respir Cell Mol Biol] 2023 Apr; Vol. 68 (4), pp. 358-365.