First-line treatment with infliximab versus conventional treatment in children with newly diagnosed moderate-to-severe Crohn's disease

Autor: Michail Doukas, Merel van Pieterson, Sarah T A Teklenburg-Roord, Herbert M. van Wering, Lissy de Ridder, Dimitris Rizopoulos, Martinus A. Cozijnsen, Maria M E Jongsma, Obbe F. Norbruis, Michiel P. van Wijk, Marco W.J. Schreurs, Thalia Hummel, Johanna C. Escher, Janneke M. Stapelbroek, Michael Groeneweg, Kaija-Leena Kolho, Cathelijne van der Feen, Iva Hojsak, Tim G. J. de Meij, Janneke N. Samsom, M Aardoom, Victorien M. Wolters, Patrick F. van Rheenen

Publikováno v: Jongsma, M M E, Aardoom, M A, Cozijnsen, M A, van Pieterson, M, de Meij, T, Groeneweg, M, Norbruis, O F, Wolters, V M, van Wering, H M, Hojsak, I, Kolho, K-L, Hummel, T, Stapelbroek, J, van der Feen, C, van Rheenen, P F, van Wijk, M P, Teklenburg-Roord, S T A, Schreurs, M W J, Rizopoulos, D, Doukas, M, Escher, J C, Samsom, J N & de Ridder, L 2022, ' First-line treatment with infliximab versus conventional treatment in children with newly diagnosed moderate-to-severe Crohn's disease: An open-label multicentre randomised controlled trial ', Gut, vol. 71, no. 1, pp. 34-42 . https://doi.org/10.1136/gutjnl-2020-322339
Gut, 71(1), 34-42. BMJ Publishing Group
Gut, 71, 34-42. BMJ PUBLISHING GROUP

ObjectiveIn newly diagnosed paediatric patients with moderate-to-severe Crohn’s disease (CD), infliximab (IFX) is initiated once exclusive enteral nutrition (EEN), corticosteroid and immunomodulator therapies have failed. We aimed to investigate wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93914d348c2a22b66f695b3bebbf019e
https://doi.org/10.1136/gutjnl-2020-322339

Safety of Thioguanine in Pediatric Inflammatory Bowel Disease: A Multi-Center Case Series

Autor: Ahmed B, Bayoumy, Jasmijn Z, Jagt, Herbert M, van Wering, Lissy, de Ridder, Thalia, Hummel, Victorien M, Wolters, Janneke, Stapelbroek, Marc A, Benninga, Chris J J, Mulder, Nanne K H, de Boer, Tim G J, de Meij

Publikováno v: Journal of pediatric gastroenterology and nutrition. 75(6)

Thioguanine (TG) has been shown as a safe alternative in adults with inflammatory bowel disease (IBD) who did not tolerate conventional thiopurines [azathioprine (AZA)/mercaptopurine]. However, data in pediatric IBD are scarce. Therefore, we aimed to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f07903875690e0874be95832f4846818
https://pubmed.ncbi.nlm.nih.gov/36136124

Food or medication? The therapeutic effects of food on the duration and incidence of upper respiratory tract infections: a Review of the literature

Autor: Ellen J. van der Gaag, Thalia Hummel

Publikováno v: Critical Reviews in Food Science and Nutrition. Taylor & Francis

PURPOSE:Upper respiratory tract infections are common in children and adults. Antiviral treatments are only available for specific groups of patients, stimulating the distribution of over-the-counter medication to relieve the symptoms for the other p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a77f2a59d81cd2f3884d6e409170eca9
https://research.utwente.nl/en/publications/5ce2f38f-ecdb-4514-9ef1-f08deb5bf4e1

Test Strategies to Predict Inflammatory Bowel Disease Among Children With Nonbloody Diarrhea

Autor: Anke Heida, Zehre Yuksel, Henkjan J. Verkade, Thalia Hummel, Solomon Ioannou, Stephanie Van Biervliet, Gieneke Gonera-de Jong, Patrick F. van Rheenen, Renate Schulenberg, Anneke C. Muller Kobold, Els Van de Vijver

Publikováno v: Pediatrics

This multicenter cohort study presents a diagnostic strategy that reliably distinguishes children presenting with symptoms of functional gastrointestinal disorders from those with nonbloody IBD. BrightcoveDefaultPlayer10.1542/6158596077001PEDS-VA_201

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6c81d8c49b33f48ddc5ba44fc8c0ca7
https://doi.org/10.1542/peds.2019-2235

Malnutrition in an obese world: Can a dietary intervention improve iron status in pre-school children?

Autor: Ellen J. van der Gaag, Kim Grootelaar, Thalia Hummel

Publikováno v: Proceedings of the Nutrition Society. 79

Introduction:In previous studies iron deficiency was present in preschool children in the developed world1. The objective of this randomized controlled trial was to investigate whether iron deficiency was present in pre-school children and to what ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0b424e85b148bbf45a35dddaf5802316
https://doi.org/10.1017/s0029665120003316