Zobrazeno 1 - 10
of 664
pro vyhledávání: '"Thakker, D R"'
Autor:
Buening, M. K., Wislocki, P. G., Levin, W., Yagi, H., Thakker, D. R., Akagi, H., Koreeda, M., Jerina, D. M., Conney, A. H.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1978 Nov 01. 75(11), 5358-5361.
Externí odkaz:
https://www.jstor.org/stable/68629
Autor:
Chang, R. L., Wood, A. W., Levin, W., Mah, H. D., Thakker, D. R., Jerina, D. M., Conney, A. H.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1979 Sep 01. 76(9), 4280-4284.
Externí odkaz:
https://www.jstor.org/stable/70068
Autor:
Thakker, D. R.1, Natt, F.2, Hüsken, D.2, van der Putten, H.1, Maier, R.1, Hoyer, D.1,3, Cryan, J. F.1 john_f.cryan@novartis.com
Publikováno v:
Molecular Psychiatry. Aug2005, Vol. 10 Issue 8, p782-789. 8p.
Autor:
Cui, Yuting1 (AUTHOR), Zhang, Xiaomin1 (AUTHOR), Liu, Jing1 (AUTHOR), Hou, Yuli1 (AUTHOR), Song, Qiao1 (AUTHOR), Cao, Min2 (AUTHOR), Zhang, Jingjing1 (AUTHOR), Wang, Xiaoling1 (AUTHOR), Liu, Congcong1 (AUTHOR), Wang, Peichang1 (AUTHOR) pcw1905@126.com, Wang, Yaqi1 (AUTHOR) wangyaqi0619@163.com
Publikováno v:
Aging Cell. Oct2024, Vol. 23 Issue 10, p1-15. 15p.
Metformin is the frontline therapy for type II diabetes mellitus. The oral bioavailability of metformin is unexpectedly high, between 40 and 60%, given its hydrophilicity and positive charge at all physiologic pH values. Previous studies in Caco-2 ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5061aa5bb0d4f307d2e320ea054af8ff
Autor:
Proctor, W. R., Thakker, D. R., Gnoth, M. J., Han, T., Swift, B., Lee, J. K., Radtke, M., Lang, D., Nebot, N., Brouwer, K. L. R.
Sorafenib is an orally active tyrosine kinase inhibitor used in the treatment of renal and hepatocellular carcinoma. This study was designed to establish whether transport proteins are involved in the hepatic uptake of sorafenib and to determine the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::798b6ba1e281fd85fd05d0fd8adb4179
Autor:
Han, T., Proctor, W. R., Ng, C. M., Brouwer, K. L. R., Costales, C. L., Everett, R. S., Thakker, D. R.
Organic cation transporters (OCTs) are members of the solute carrier 22 family of transporter proteins that are involved in absorption, distribution, and excretion of organic cations. OCT3 is localized in the apical (AP) membrane of enterocytes, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12f6b62cc32e52e68727d62bbab4d235
Autor:
Jinadasa, A. G. R. Greshamali1 (AUTHOR), Akalanka, H. M. Kasuni2 (AUTHOR) kasuniakalanka@sjp.ac.lk, Wageesha, N. D. Amal3 (AUTHOR), Ekanayake, Sagarika4 (AUTHOR), Shanbhag, Vinit (AUTHOR) vcs36d@missouri.edu
Publikováno v:
International Journal of Breast Cancer. 8/27/2024, Vol. 2024, p1-8. 8p.
Autor:
Yanni, S. B., Thakker, D. R., Augustijns, P. F., Annaert, P. P., Benjamin, D. K., Brouwer, K. L. R.
The purpose of the present study was to elucidate the transport mechanisms responsible for elimination of micafungin, a new semisynthetic echinocandin antifungal agent, which is predominantly cleared by biliary excretion in humans and rats. In vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4764d52581d066613fa37b6c49c7e198
Autor:
Annaert, P. P., Augustijns, P., Yanni, S. B., Thakker, D. R., Benjamin, D. K., Bridges, A., Gao, Y.
Voriconazole is a potent second generation triazole antifungal agent with broad-spectrum activity against clinically important fungi. It is cleared predominantly via metabolism in all species tested including humans. N-oxidation of the fluoropyrimidi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0c9481b1c0a000e27ff4a6071aa00e9