Bone dysplasia in Hutchinson-Gilford progeria syndrome is associated with dysregulated differentiation and function of bone cell populations.

Autor: Cabral WA; Molecular Genetics Section, Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, Maryland, USA., Stephan C; Departments of Orthopedic Surgery and Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA., Terajima M; Division of Oral and Craniofacial Health Sciences, Adams School of Dentistry, University of North Carolina, Chapel Hill, North Carolina, USA., Thaivalappil AA; Molecular Genetics Section, Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, Maryland, USA., Blanchard O; Departments of Orthopedic Surgery and Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA., Tavarez UL; Molecular Genetics Section, Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, Maryland, USA., Narisu N; Molecular Genetics Section, Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, Maryland, USA., Yan T; Molecular Genetics Section, Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, Maryland, USA., Wincovitch SM; Cytogenetics and Microscopy Core, National Human Genome Research Institute, NIH, Bethesda, Maryland, USA., Taga Y; Nippi Research Institute of Biomatrix, Ibaraki, Japan., Yamauchi M; Division of Oral and Craniofacial Health Sciences, Adams School of Dentistry, University of North Carolina, Chapel Hill, North Carolina, USA., Kozloff KM; Departments of Orthopedic Surgery and Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA., Erdos MR; Molecular Genetics Section, Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, Maryland, USA., Collins FS; Molecular Genetics Section, Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, Maryland, USA.

Publikováno v: Aging cell [Aging Cell] 2023 Sep; Vol. 22 (9), pp. e13903. Date of Electronic Publication: 2023 Jun 26.