Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Thaissa L. Silva"'
Autor:
Eduardo Caio Torres-Santos, Débora de Souza Costa, Danyelle C. Santos, Valter Viana Andrade-Neto, Thaissa L. Silva, Marina Amaral Alves, Alan H. Fairlamb, Edézio Ferreira Cunha-Júnior, Paulo R. R. Costa, Marília O. F. Goulart, Ayres G. Dias, Susan Wyllie, Juliana da Silva Pacheco
Publikováno v:
ACS Med Chem Lett
[Image: see text] 5-Nitro-furan nitrones (1) and 5-nitro-thiophene nitrones (2) were synthesized in one step. Compounds 1a–c had the most potent leishmanicidal activity against intracellular amastigote forms of Leishmania amazonensis and L. infantu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36771859ab18b4684d9de6f221ab55bf
https://doi.org/10.1021/acsmedchemlett.1c00193
https://doi.org/10.1021/acsmedchemlett.1c00193
Autor:
Danyelle Cândido Santos, Júlio C.S. da Silva, Thaissa L. Silva, Marília O. F. Goulart, Jay D. Wadhawan, Shaiani Maria Gil de Melo, Flavio da Silva Emery, Andresa K.A. de Almeida, Tamires Alves do Nascimento, André Felipe de Almeida Xavier, Jadriane A. Xavier
Publikováno v:
ChemElectroChem. 8:2921-2934
4,4-difluoro-5,7-dimethyl-4-bora-3a,4a-diaza-s-indacene (BODIPY) and derivatives are an outstanding class of fluorescent dyes. Herein, we report on the introduction of a nitrosyl moiety into the BODIPY structure and its dramatic effect on the observe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86e577fb07f5d140b7c45794454ed5c3
https://doi.org/10.1002/celc.202100609
https://doi.org/10.1002/celc.202100609
Autor:
Danyelle C. Santos, Christian Amatore, Maria de Lourdes S.G. de Azevedo, Thaissa L. Silva, Marília O. F. Goulart, Fabricia da Rocha Ferreira
Publikováno v:
Current Opinion in Electrochemistry. 24:79-87
Molecular electrochemistry is closely linked to life sciences. Electron transfers play important roles in the bioactivation of redox-active drugs, in their metabolism/catabolism, and in their targeted release at precise destinations and frequently pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afa4619f8342de67d23917075c1afc8f
https://doi.org/10.1016/j.coelec.2020.06.011
https://doi.org/10.1016/j.coelec.2020.06.011
Autor:
Larissa Araújo Rolim, Marília O. F. Goulart, Arlan de Assis Gonsalves, Cleônia Roberta Melo Araújo, Thaissa L. Silva, Fátima de Cássia Evangelista de Oliveira, Marcília Pinheiro da Costa, Danyelle Cândido Santos, Edigênia Cavalcante da Cruz Araújo, Délis Galvão Guimarães, Maria Francilene Souza Silva, Victória Laysna dos Anjos Santos, Claudia Pessoa
Publikováno v:
Medicinal chemistry (Shariqah (United Arab Emirates)). 17(9)
Background: Natural naphthoquinones have shown diversified biological activities including antibacterial, antifungal, antimalarial, and cytotoxic activities. However, they are also compounds with acute cytotoxicity, immunotoxicity, carcinogenesis, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9830eab05a7fe8bfb23b76cc9cf0b70a
https://pubmed.ncbi.nlm.nih.gov/32807066
https://pubmed.ncbi.nlm.nih.gov/32807066
Autor:
Rubem F. S. Menna-Barreto, Marília O. F. Goulart, Rossimiriam Pereira de Freitas, Willian X. C. Oliveira, Thaissa L. Silva, Eufrânio N. da Silva Júnior, Guilherme A. M. Jardim
Publikováno v:
Organic & Biomolecular Chemistry. 16:1686-1691
We report a sequential C–H iodination/organoyl-thiolation of naphthoquinones and their relevant trypanocidal activity. Under a combination of AgSR with a copper source, sulfur-substituted benzenoid quinones were prepared in high yields (generally >
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a3f4f928f60db1b3bdf10728770b5da
https://doi.org/10.1039/c8ob00196k
https://doi.org/10.1039/c8ob00196k
Autor:
Thaissa L. Silva, Eduardo Caio Torres-Santos, Andre Felippe de Almeida Xavier, Anastacio Boane, Camila Calado de Vasconcelos, Ricardo Alexandre Gomes dos Santos, Jadriane A. Xavier, Marília O. F. Goulart
Publikováno v:
Current Opinion in Electrochemistry. 29:100740
This review discusses the state of the art, challenges, and perspectives in recent applications of nitroaromatics and nitroheteroaromatics, which are redox-bio-activated drugs or leads, in Medicinal Chemistry. It deals mainly with the electrochemical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6200aa832d58b713d0f7ac4c6d81976d
https://doi.org/10.1016/j.coelec.2021.100740
https://doi.org/10.1016/j.coelec.2021.100740
Autor:
Paulo R. R. Costa, Thaissa L. Silva, Danyelle C. Santos, Dimas J. P. Lima, Marília O. F. Goulart, Fabricia da Rocha Ferreira, Camila Calado de Vasconcelos, Chaquip D. Netto, Júlio C.S. da Silva
Publikováno v:
Journal of the Brazilian Chemical Society v.30 n.11 2019
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Journal of the Brazilian Chemical Society, Volume: 30, Issue: 11, Pages: 2438-2451, Published: 24 OCT 2019
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Journal of the Brazilian Chemical Society, Volume: 30, Issue: 11, Pages: 2438-2451, Published: 24 OCT 2019
Electrochemical methods are considered useful tools for simulations of biological redox reactions. The activities of quinones depend on their bioreduction. Biologically active pterocarpanquinones LQB-149 (nitroderivative), 150 and 151 (bromo and chlo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f47337e0884ca71b3a4ffc8c7d0f579b
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532019001102438
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532019001102438
Autor:
Maria Francilene Souza Silva, Vitor F. Ferreira, Claudia Pessoa, Andre Felippe de Almeida Xavier, Yen G. de Paiva, Mariana F. C. Cardoso, Marília O. F. Goulart, Daniel Pascoalino Pinheiro, Fernando de C. da Silva, Thaissa L. Silva
Publikováno v:
Journal of the Brazilian Chemical Society. 30
Electrochemical methods are powerful in the characterization and design of redox-modulating agents. We, herein, report the electrochemical investigation, in aprotic medium, of eleven synthetic 3-thio-substituted-nor-beta-lapachones, along with the de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90c898a54be2a19473584542f40d075d
https://doi.org/10.21577/0103-5053.20180248
https://doi.org/10.21577/0103-5053.20180248
Autor:
Marília O. F. Goulart, Thaissa L. Silva, Chaquip D. Netto, Fabricia da Rocha Ferreira, Paulo R. R. Costa, Camila Calado de Vasconcelos, Rosanny Christhinny Da Silva, Dimas J. P. Lima
Publikováno v:
ChemElectroChem. 3:2252-2263
The electrochemistry of a redox-based bioactive pterocarpanquinone, designated as LQB-118, and its precursor chromenquinone (CQ) was investigated in protic and aprotic media with a focus on the reduction mechanism in both media, the reactivity with o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c87cf9636a04b24ed235a8069003ea34
https://doi.org/10.1002/celc.201600504
https://doi.org/10.1002/celc.201600504
Autor:
Olivier Buriez, Eric Labbé, Yen G. de Paiva, Marília O. F. Goulart, Fabricia da Rocha Ferreira, Christian Amatore, Thaissa L. Silva
Publikováno v:
Current Topics in Medicinal Chemistry. 15:136-162
This review discusses the state of the art, challenges and perspectives in recent applications of electrochemistry in the life sciences. It deals mainly with the elucidation of molecular mechanisms of drug action, drug design and development, involvi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4837887bfc72d61f0cfeeb4a6eb38adb
https://doi.org/10.2174/1568026615666141209155300
https://doi.org/10.2174/1568026615666141209155300