Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Thaise Gonçalves Araújo"'
Autor:
Paula Marynella Alves Pereira Lima, Priscila Capelari Orsonlin, Nayane Moreira Machado, Rosiane Gomes Silva Oliveira, Lorena Polloni, Raquel Pereira Cruz, Janaína do Couto Almeida, Robson José de Oliveira Júnior, Wendell Guerra, Thaise Gonçalves Araújo
Publikováno v:
Genetics and Molecular Biology, Vol 47, Iss 3 (2024)
Abstract Chemotherapy stands out as the main systemic treatment strategy against cancer and still faces problems related to multidrug resistance and severe side effects. Copper-based drugs have been widely explored in medicinal chemistry, since coppe
Externí odkaz:
https://doaj.org/article/7596ba358ab84b0aa68758f53923bca8
Autor:
Fernanda Cardoso da Silva, Douglas Cardoso Brandão, Everton Allan Ferreira, Raoni Pais Siqueira, Helen Soares Valença Ferreira, Ademar Alves Da Silva Filho, Thaise Gonçalves Araújo
Publikováno v:
Pharmaceuticals, Vol 16, Iss 10, p 1466 (2023)
Breast cancer (BC) is the most diagnosed cancer worldwide, mainly affecting the epithelial cells from the mammary glands. When it expresses the estrogen receptor (ER), the tumor is called luminal BC, which is eligible for endocrine therapy with hormo
Externí odkaz:
https://doaj.org/article/e66c7dd405254cc2a57109c58f607d04
Autor:
Pedro Henrique Alves Machado, Drielly Aparecida Paixão, Ricardo Campos Lino, Tiago Rodrigues de Souza, Nayara Júnia de Souza Bontempo, Luana Munique Sousa, Fernanda Van Petten de Vasconcelos Azevedo, Priscila Capelari Orsolin, Paula Marynella Alves Pereira Lima, Isabella Castro Martins, Joyce Ferreira da Costa Guerra, Samuel Cota Teixeira, Thaise Gonçalves Araújo, Luiz Ricardo Goulart, Sandra Morelli, Wendell Guerra, Robson José de Oliveira Júnior
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract The thin line between efficacy and toxicity has challenged cancer therapy. As copper is an essential micronutrient and is important to tumor biology, CuII complexes emerged as an alternative to chemotherapy; however, its biological propertie
Externí odkaz:
https://doaj.org/article/8931fbabddd844fe9fbd314bdb81b6a3
Autor:
Lara Vecchi, Sara Teixeira Soares Mota, Mariana Alves Pereira Zóia, Isabella Castro Martins, Jessica Brito de Souza, Tiago Góss Santos, Adriano de Oliveira Beserra, Victor Piana de Andrade, Luiz Ricardo Goulart, Thaise Gonçalves Araújo
Publikováno v:
Cells, Vol 11, Iss 10, p 1705 (2022)
Annexin A1 (AnxA1) is a pleiotropic protein that exerts essential roles in breast cancer (BC) growth and aggressiveness. In our previous work, we described the autocrine signaling of AnxA1 through formyl peptide receptor 1 (FPR1) in the triple-negati
Externí odkaz:
https://doaj.org/article/c8cebaa8f37d41f393595f4c1d65c01f
Autor:
Thaise Gonçalves Araújo, Sara Teixeira Soares Mota, Helen Soares Valença Ferreira, Matheus Alves Ribeiro, Luiz Ricardo Goulart, Lara Vecchi
Publikováno v:
Cells, Vol 10, Iss 9, p 2245 (2021)
Annexin A1 is a 37 kDa phospholipid-binding protein that is expressed in many tissues and cell types, including leukocytes, lymphocytes and epithelial cells. Although Annexin A1 has been extensively studied for its anti-inflammatory activity, it has
Externí odkaz:
https://doaj.org/article/86301f41f936439581010cbbb51f2cc4
Autor:
Lara Vecchi, Thaise Gonçalves Araújo, Fernanda Van Petten de Vasconcelos Azevedo, Sara Teixeria Soares Mota, Veridiana de Melo Rodrigues Ávila, Matheus Alves Ribeiro, Luiz Ricardo Goulart
Publikováno v:
Cells, Vol 10, Iss 6, p 1472 (2021)
Phospholipids are suggested to drive tumorigenesis through their essential role in inflammation. Phospholipase A2 (PLA2) is a phospholipid metabolizing enzyme that releases free fatty acids, mostly arachidonic acid, and lysophospholipids, which contr
Externí odkaz:
https://doaj.org/article/e72fb1d4d17c4579a4d925a2e164bb5a
Publikováno v:
Evidência, Vol 14, Iss 2 (2014)
A biossegurança envolve ações preventivas contra os riscos provenientes do desenvolvimento científico e tecnológico, visando à proteção dos seres vivos e do ambiente. Conceitos e práticas embasados nessa ciência são exigidos para entender
Externí odkaz:
https://doaj.org/article/84b37a663c99415fa948cc24b1f9f248
Autor:
Thaise Gonçalves Araújo, Gabriela da Silva Guimarães, Antonielle Oliveira Cordeiro, Matheus Coutinho Gazolla, Lara Vecchi, Mariana Alves Pereira Zoia, Fernanda Van Petten de Vasconcelos Azevedo, Igor Moreira Campos, Danilo de Souza Costa, Sara Teixeira Soares Mota, Matheus Alves Ribeiro, Luiz Ricardo Goulart, Ademar Alves da Silva Filho
Publikováno v:
Current Topics in Medicinal Chemistry. 23
Background: Effective cancer treatment still challenges medicine since the strategies employed so far are not sufficiently safe and capable of specifically eliminating tumor cells. Prostate cancer (PCa) is a highly incident malignant neoplasm, and th
Autor:
Matheus Alves Ribeiro, Fabrícia de Matos Oliveira, Douglas Alexander Alvos, Lara Vecchi, Thaise Gonçalves Araújo
Publikováno v:
Interação. 21:166-186
Epidemiological data on death rates and incidence of Breast Cancer (BC) are still alarming, highlighting the need for new strategies of diagnosis and therapy. Our group has previously described a new antibody in Fab format, FabC4, for diagnostics, st
Autor:
Dayanne Silva Borges, Lara Vecchi, Deysse Carla Tolentino Barros, Vinícius Marques Arruda, Helen Soares Valença Ferreira, Matheus Fernandes da Silva, Joyce Ferreira da Costa Guerra, Raoni Pais Siqueira, Thaise Gonçalves Araújo
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 7; Pages: 6323
Glyphosate (GLY) was developed in the early 1970s and has become the most used broad-spectrum herbicide in the world so far. Its main metabolite is aminomethylphosphonic acid (AMPA), and the accumulation of GLY and its derivative compounds raises som